Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Egbert K. O. Kruithof"'
Autor:
Sylvie Dunoyer-Geindre, Anne-Sophie Rivier-Cordey, Carlos Caetano, Richard J Fish, Egbert K O Kruithof
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167588 (2016)
Expression of the tissue-type plasminogen activator gene (t-PA; gene name PLAT) is regulated, in part, by epigenetic mechanisms. We investigated the relationship between PLAT methylation and PLAT expression in five primary human cell types and six tr
Externí odkaz:
https://doaj.org/article/971a3973552c4fb99ef0621ab79dd117
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80743 (2013)
Localization of Toll-like receptors (TLR) in subcellular organelles is a major strategy to regulate innate immune responses. While TLR4, a cell-surface receptor, signals from both the plasma membrane and endosomal compartments, less is known about th
Externí odkaz:
https://doaj.org/article/069241185f374cc58c2e12173649df8a
Publikováno v:
Cardiovascular Research, Vol. 90, No 3 (2011) pp. 457-63
Cardiovascular research
Cardiovascular research
Aims Tissue-type plasminogen activator (t-PA) is produced by endothelial cells (EC) and is responsible for the removal of intravascular fibrin deposits. We investigated whether expression of t-PA by EC is under epigenetic control. Methods and results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d74d00f0995ff382c4671138dfe0327
http://doc.rero.ch/record/296785/files/cvr028.pdf
http://doc.rero.ch/record/296785/files/cvr028.pdf
Autor:
Jean-Marie Tiercy, Egbert K. O. Kruithof, Céline Fickentscher, Karim J. Brandt, Philippe de Moerloose, Françoise Boehlen
Publikováno v:
Haematologica
Haematologica, Vol. 102, No 8 (2017) pp. 1324-1332
Haematologica, Vol. 102, No 8 (2017) pp. 1324-1332
Antiphospholipid antibody syndrome is an autoimmune disease characterized by the presence of so-called antiphospholipid antibodies and clinical manifestations such as recurrent thromboembolic or pregnancy complications. Although the main antigenic de
Autor:
Anne-Sophie Rivier-Cordey, Sylvie Dunoyer-Geindre, Carlos Caetano, Egbert K. O. Kruithof, Richard J. Fish
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167588 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167588 (2016)
Expression of the tissue-type plasminogen activator gene (t-PA; gene name PLAT) is regulated, in part, by epigenetic mechanisms. We investigated the relationship between PLAT methylation and PLAT expression in five primary human cell types and six tr
Publikováno v:
Thrombosis Research. 132:408-413
The antiphospholipid syndrome (APS) is an autoimmune disease associated with arterial or venous thrombosis and/or recurrent fetal loss and is caused by pathogenic antiphospholipid antibodies (aPLA). The plasma protein β2-glycoprotein 1 (β2GP1) has
Autor:
Martina Barnevik Olsson, Richard L.M. Faull, Sylvie Dunoyer-Geindre, Christina Jern, Karin Hultman, Egbert K. O. Kruithof, Maurice A. Curtis
Publikováno v:
Gene Regulation and Systems Biology, Vol 10 (2016)
Gene Regulation and Systems Biology, Vol 2016, Iss 10, Pp 9-13 (2016)
Gene Regulation and Systems Biology
Gene Regulation and Systems Biology, Vol 2016, Iss 10, Pp 9-13 (2016)
Gene Regulation and Systems Biology
The serine protease tissue-type plasminogen activator (t-PA) is involved in both vital physiological brain processes, such as synaptic plasticity, and pathophysiological conditions, such as neurodegeneration and ischemic stroke. Recent data suggest t
Autor:
Jia Wei Liu, Françoise Dignat-George, Lucia Mazzolai, Egbert K. O. Kruithof, Karima Bouzourene, Henri Bounameaux, Sylvie Dunoyer-Geindre, Daniel Hayoz
Publikováno v:
Journal of vascular research
Journal of Vascular Research, Vol. 48, No 5 (2011) pp. 443-51
Journal of Vascular Research, Vol. 48, No 5 (2011) pp. 443-51
Background: Endothelial progenitor-derived cells (EPC) are a cell therapy tool in peripheral arterial disease and for re-endothelialization of bypasses and stents. Objective: To assess EPC behavior under flow conditions normally found in vivo. Result
Autor:
Sylvie Dunoyer-Geindre, Guido Reber, Françoise Boehlen, Céline Fickentscher, Danielle Burger, Philippe de Moerloose, Egbert K. O. Kruithof, Nathalie Satta
Publikováno v:
Blood
Blood, Vol. 117, No 20 (2011) pp. 5523-31
Blood, Vol. 117, No 20 (2011) pp. 5523-31
The presence of antiphospholipid antibodies (aPLAs) is associated with arterial or venous thrombosis and/or recurrent fetal loss. The proposed pathogenic mechanisms for aPLA effects include the inflammatory activation of monocytes and endothelial cel
Autor:
Bertil Rydenhag, Christina Jern, Anna Tjärnlund-Wolf, Egbert K. O. Kruithof, Karin Hultman, Ulrika Wilhelmsson, Richard J. Fish, Milos Pekny
Publikováno v:
Journal of Thrombosis and Haemostasis, Vol. 6, No 10 (2008) pp. 1796-803
Summary. Background: Emerging data demonstrate important roles for tissue-type plasminogen activator (t-PA) in the central nervous system (CNS). In contrast to endothelial cells, little is known about the regulation of t-PA gene expression and secret