Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Egbert Flory"'
Autor:
Samuel A. Theuerkauf, Alexander Michels, Vanessa Riechert, Thorsten J. Maier, Egbert Flory, Klaus Cichutek, Christian J. Buchholz
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102170- (2021)
Summary: Cell entry of the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mediated by its spike protein S. As a main antigenic determinant, S protein is in focus of various therapeutic strategies. Besides particle-cell fusio
Externí odkaz:
https://doaj.org/article/e48a0ae93a7b4dc49409fecb77e7e564
Autor:
André Berger, Andreas F R Sommer, Jenny Zwarg, Matthias Hamdorf, Karin Welzel, Nicole Esly, Sylvia Panitz, Andreas Reuter, Irene Ramos, Asavari Jatiani, Lubbertus C F Mulder, Ana Fernandez-Sesma, Frank Rutsch, Viviana Simon, Renate König, Egbert Flory
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002425 (2011)
Myeloid blood cells are largely resistant to infection with human immunodeficiency virus type 1 (HIV-1). Recently, it was reported that Vpx from HIV-2/SIVsm facilitates infection of these cells by counteracting the host restriction factor SAMHD1. Her
Externí odkaz:
https://doaj.org/article/a25138a23dde4fd5b01d7754d13c5a24
Autor:
Egbert Flory, Thorsten J. Maier, Klaus Cichutek, Samuel A. Theuerkauf, Vanessa Riechert, Alexander Michels, Christian J. Buchholz
Publikováno v:
iScience, 24(3):102170
iScience
iScience, Vol 24, Iss 3, Pp 102170-(2021)
iScience
iScience, Vol 24, Iss 3, Pp 102170-(2021)
Cell entry of the pandemic virus SARS-CoV-2 is mediated by its spike protein S. As main antigenic determinant, S protein is in focus of various therapeutic strategies. Besides particle-cell fusion, S mediates fusion between infected and uninfected ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1008314db7b04665d7a8863a684474
https://doi.org/10.1101/2020.10.15.340604
https://doi.org/10.1101/2020.10.15.340604
Autor:
Jürgen Scherer, Egbert Flory
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 58:1201-1206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d84cd07354e63d73a3f8492c2adb774
https://doi.org/10.1007/s00103-015-2235-1
https://doi.org/10.1007/s00103-015-2235-1
Autor:
Metoda Lipnik-Stangelj, Patrick Celis, Ilona Reischl, Paula Salmikangas, Jean-Hugues Trouvin, Guido Pante, Janis Ancans, Sol Ruiz, Egbert Flory, Asterios S. Tsiftsoglou, Margarida Menezes-Ferreira, Jan Kyselovic, John Joseph Borg, Marcos Timon, Christian Schneider, Dariusz Sladowski
Publikováno v:
Regenerative Medicine. 10:65-78
During the past decade, a large number of cell-based medicinal products have been tested in clinical trials for the treatment of various diseases and tissue defects. However, licensed products and those approaching marketing authorization are still f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a7eca7de7948eea46b63af7b465681
https://doi.org/10.2217/rme.14.65
https://doi.org/10.2217/rme.14.65
Autor:
Renate König, Adam Idica, Maximilian Riess, Egbert Flory, Irene M. Pedersen, Matthias Hamdorf, Nina V. Fuchs
SAMHD1 is a phosphohydrolase maintaining cellular dNTP homeostasis but also acts as a critical regulator in innate immune responses due to its antiviral activity and association with autoimmune disease, leading to aberrant activation of interferon. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebf04d8496e3512127aeed5632915bc
https://europepmc.org/articles/PMC5217685/
https://europepmc.org/articles/PMC5217685/
Autor:
Jan-Hendrik Trösemeier, Axel V. Horn, Gerald G. Schumann, Robert A. Jabulowsky, Carsten Münk, Johannes Löwer, Kay-Martin Hanschmann, Henning Hofmann, André Berger, Sabine Klawitter, Anja Bock, Ananda Ayyappan Jaguva Vasudevan, Egbert Flory, Jeffrey S. Han, Roswitha Löwer, Ulrike Held
Publikováno v:
Nucleic Acids Research
LINE-1 (L1) retrotransposons are mobile genetic elements whose extensive proliferation resulted in the generation of ≈ 34% of the human genome. They have been shown to be a cause of single-gene diseases. Moreover, L1-encoded endonuclease can elicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6f44f06f408885c41f27329d8d305c
http://europepmc.org/articles/PMC3874205
http://europepmc.org/articles/PMC3874205
Autor:
Jens Reinhardt, Egbert Flory
Publikováno v:
Transfusion Medicine and Hemotherapy. 40:409-412
Increasing scientific knowledge and technical innovations in the areas of cell biology, biotechnology and medicine resulted in the development of promising therapeutic approaches for the prevention and treatment of human diseases. Advanced therapy me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bd680de8bf04874b8ff0db218df32b
https://doi.org/10.1159/000356364
https://doi.org/10.1159/000356364
Autor:
Juliane Liese, Maximilian Riess, Karin Welzel, Malin Finkernagel, Carsten Münk, Kerstin Schott, Caitlin Shepard, Christian Donnerhak, Bingqian Qu, Nadja Kettern, Kiyoshi Himmelsbach, Lise Rivière, Egbert Flory, Baek Kim, Yi Ni, Renate König, Andreas F. R. Sommer, Esther Schnellbächer, Stephan Urban
Publikováno v:
Scientific Reports
Deoxynucleotide triphosphates (dNTPs) are essential for efficient hepatitis B virus (HBV) replication. Here, we investigated the influence of the restriction factor SAMHD1, a dNTP hydrolase (dNTPase) and RNase, on HBV replication. We demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0ba5b1379b0edc270faf895bd6d831
https://doi.org/10.1038/srep26616
https://doi.org/10.1038/srep26616
Autor:
Brigitte Anliker, Matthias Schweizer, Egbert Flory, Zoltán Ivics, Jürgen Scherer, Matthias Renner, Martina Schüßler-Lenz
Publikováno v:
Gene Therapy and Cell Therapy Through the Liver ISBN: 9784431556657
An important step in the regulation of cell and gene therapy medicinal products, which are classified as advanced therapy medicinal products (ATMPs) in the European Union, has been made with Regulation 1394/2007/EC. By this regulation a new committee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96becfffbd3528f1022ac6c2e2c32418
https://doi.org/10.1007/978-4-431-55666-4_10
https://doi.org/10.1007/978-4-431-55666-4_10