Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Egbert, Oosterwijk"'
Autor:
J Alfred Witjes, Alina Vrieling, Mihai G Netea, Leo A B Joosten, Katja K H Aben, Sita H Vermeulen, Joost L Boormans, Antoine G van der Heijden, Boris Novakovic, Jelmer H van Puffelen, Liesbeth van Emst, Denise Kooper, Tahlita C M Zuiverloon, Ursula T H Oldenhof, Tessel E Galesloot, Lambertus A L M Kiemeney, Egbert Oosterwijk
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background BCG is recommended as intravesical immunotherapy to reduce the risk of tumor recurrence in patients with non-muscle invasive bladder cancer (NMIBC). Currently, it is unknown whether intravesical BCG application induces trained immunity.Met
Externí odkaz:
https://doaj.org/article/f160d417e5fc4088a9372dbbdff54fa8
Autor:
Jeannette C. Oosterwijk-Wakka, Mirjam C.A. de Weijert, Gerben M. Franssen, Dimitar R. Kolev, Ton A.F.J. de Haan, Otto C. Boerman, Peter F.A. Mulders, Egbert Oosterwijk
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100826- (2022)
Sunitinib is an effective treatment for patients with metastatic Renal Cell Carcinoma (mRCC) but ultimately resistance occurs. The aim of this study was to investigate sunitinib resistance in RCCs and to develop therapeutic combination strategies wit
Externí odkaz:
https://doaj.org/article/a3206bae57544db090053ce0eb8b6ee7
Autor:
Kirsten B. Kluivers, Sabrina L. Lince, Alejandra M. Ruiz-Zapata, Wilke M. Post, Rufus Cartwright, Manon H. Kerkhof, Joanna Widomska, Ward De Witte, Jakub Pecanka, Lambertus A. Kiemeney, Sita H. Vermeulen, Jelle J. Goeman, Kristina Allen-Brady, Egbert Oosterwijk, Geert Poelmans
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6087 (2023)
Pelvic organ prolapse (POP) represents a major health care burden in women, but its underlying pathophysiological mechanisms have not been elucidated. We first used a case-control design to perform an exome chip study in 526 women with POP and 960 co
Externí odkaz:
https://doaj.org/article/810fea8f4978417683d84cef194689a4
Autor:
Iris S. G. Brummelhuis, Michiel Simons, Lars H. Lindner, Simone Kort, Sytse de Jong, Martin Hossann, J. Alfred Witjes, Egbert Oosterwijk
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 1415-1424 (2021)
Purpose Recommended treatments for muscle-invasive bladder cancer (MIBC) come with considerable morbidity. Hyperthermia (HT) triggered drug release from phosphatidylglycerol-based thermosensitive liposomes (DPPG2-TSL) might prevent surgical bladder r
Externí odkaz:
https://doaj.org/article/d272d181c1754126b8c5cb777cef5338
Autor:
Michiel W. Pot, Silvia M. Mihaila, Dana te Brinke, Guus van der Borg, Egbert Oosterwijk, Willeke F. Daamen, Toin H. van Kuppevelt
Publikováno v:
ACS Omega, Vol 5, Iss 8, Pp 3908-3916 (2020)
Externí odkaz:
https://doaj.org/article/53d194aa9bf64bc4b5a8b3628342cf5b
Autor:
Johanna F.A. Husch, Laura Coquelin, Nathalie Chevallier, Dorien Tiemessen, Egbert Oosterwijk, René van Rheden, Charlotte Woud, Jurriaan Vossen, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken
Publikováno v:
Tissue Engineering. Part C: Methods, 29, 216-227
Tissue Engineering. Part C: Methods, 29, 5, pp. 216-227
Tissue Engineering. Part C: Methods, 29, 5, pp. 216-227
Item does not contain fulltext Stromal vascular fraction (SVF) is the primary isolate obtained after enzymatic digestion of adipose tissue that contains various cell types. Its successful application for cell-based construct preparation in an intra-o
Autor:
Vera P Mourits, Jelmer H vanPuffelen, Boris Novakovic, Mariolina Bruno, Anaísa V Ferreira, Rob JW Arts, Laszlo Groh, Tania O Crișan, Jelle Zwaag, Elisa Jentho, Matthijs Kox, Peter Pickkers, Frank L van deVeerdonk, Sebastian Weis, Egbert Oosterwijk, Sita H Vermeulen, Mihai G Netea, Leo AB Joosten
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Abstract Objectives Histone methyltransferase G9a, also known as Euchromatic Histone Lysine Methyltransferase 2 (EHMT2), mediates H3K9 methylation which is associated with transcriptional repression. It possesses immunomodulatory effects and is overe
Externí odkaz:
https://doaj.org/article/6241b566bf084db2b5a557cb91065978
Autor:
Robin I. J. Merkx, Mark Rijpkema, Gerben M. Franssen, Annemarie Kip, Bart Smeets, Alfred Morgenstern, Frank Bruchertseifer, Eddie Yan, Michael P. Wheatcroft, Egbert Oosterwijk, Peter F. A. Mulders, Sandra Heskamp
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 570 (2022)
In this study, we compared the tumor-targeting properties, therapeutic efficacy, and tolerability of the humanized anti-CAIX antibody (hG250) labeled with either the α-emitter actinium-225 (225Ac) or the β--emitter lutetium-177 (177Lu) in mice. BAL
Externí odkaz:
https://doaj.org/article/d9cc433e7203440983f0235c2ff4da3e
Autor:
Wilke M. Post, Joanna Widomska, Hilde Grens, Marieke J. H. Coenen, Frank M. J. Martens, Dick A. W. Janssen, Joanna IntHout, Geert Poelmans, Egbert Oosterwijk, Kirsten B. Kluivers
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3401 (2022)
Stress urinary incontinence (SUI) is a common and burdensome condition. Because of the large knowledge gap around the molecular processes involved in its pathophysiology, the aim of this review was to provide a systematic overview of genetic variants
Externí odkaz:
https://doaj.org/article/41b76e27a33e47239d38acb277c95ba1
Autor:
Kazuhiro Nagao, Nachi Shinohara, Frank Smit, Mirjam de Weijert, Sander Jannink, Yuji Owada, Peter Mulders, Egbert Oosterwijk, Hideyasu Matsuyama
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background To identify potential therapeutic target in clear cell renal cell carcinoma (ccRCC), we performed a transcriptome analysis. Our analysis showed that fatty acid binding protein 7 (FABP7) has the highest mean differential overexpres
Externí odkaz:
https://doaj.org/article/6a504b49891e44eb87e2b615169d35aa