Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Efthymios Manolis"'
Autor:
Efthymios Manolis, Alfredo García‐Arieta, Anders Lindahl, Evangelos Kotzagiorgis, Jobst Limberg, Øyvind Holte, Paulo Paixao, Carolien Versantvoort, Flora Musuamba Tshinanu, Kevin Blake, Michiel Van Den Heuvel
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 5, Pp 556-559 (2023)
Externí odkaz:
https://doaj.org/article/a77d355ba57d45bbaaac7700cf82f8a7
Autor:
Flora T. Musuamba, Ine Skottheim Rusten, Raphaëlle Lesage, Giulia Russo, Roberta Bursi, Luca Emili, Gaby Wangorsch, Efthymios Manolis, Kristin E. Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Cécile F. Rousseau, Emmanuelle M. Voisin, Rossana Alessandrello, Nuno Curado, Enrico Dall’ara, Blanca Rodriguez, Francesco Pappalardo, Liesbet Geris
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 804-825 (2021)
Abstract The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously recognized, international standards for their evaluation, accepted by all stakehold
Externí odkaz:
https://doaj.org/article/97e2e67f5a5b4314bf9e9f73a5497dde
Autor:
Flora T. Musuamba, Roberta Bursi, Efthymios Manolis, Kristin Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Raphaëlle Lesage, Cécile Crozatier, Emmanuelle M. Voisin, Cécile F. Rousseau, Thierry Marchal, Rossana Alessandrello, Liesbet Geris
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 195-197 (2020)
Externí odkaz:
https://doaj.org/article/8e304d8ae5af4f9299edf6995437c78f
Autor:
Cécile F. Rousseau, Kristin E. Karlsson, Raphaëlle Lesage, Eulalie Courcelles, Emmanuelle M. Voisin, Francesco Pappalardo, Nuno Curado, Enrico Dall'Ara, Flora T. Musuamba, Gaby Wangorsch, Blanca Rodriguez, Ine Skottheim Rusten, Rossana Alessandrello, Roberta Bursi, Giulia Russo, Luca Emili, Efthymios Manolis, Jean-Pierre Boissel, Liesbet Geris, Alexander Kulesza
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 804-825 (2021)
CPT: pharmacometrics & systems pharmacology, 10(8):804-825
CPT: Pharmacometrics & Systems Pharmacology
CPT: pharmacometrics & systems pharmacology, 10(8):804-825
CPT: Pharmacometrics & Systems Pharmacology
The value of in silico methods in drug development and evaluation has been demonstrated repeatedly and convincingly. While their benefits are now unanimously recognized, international standards for their evaluation, accepted by all stakeholders invol
Publikováno v:
The Journal of Clinical Pharmacology. 61
Getting the right dose regimen for children and adolescents is important but poses great scientific, practical, and ethical challenges. At the same time, the availability of data in adults is a huge advantage and needs to be used optimally when desig
Autor:
Yue-E Wu, Alison H. Thomson, Yi Zheng, José Esteban Peris, Lo Yl, Bernd Meibohm, Edmund V. Capparelli, Wei Zhao, John N. van den Anker, Irja Lutsar, Hai-Yan Shi, Hai-Yan Xu, Xiao Li, Stéphanie Leroux, Karel Allegaert, Evelyne Jacqz-Aigrain, Bo Hao Tang, Yue Zhou, Xin Huang, Xiaoling Wang, Bao-Ping Xu, Bu-Fan Yao, Jacobus Burggraaf, Nicolas Simon, A.-Dong Shen, Chen Kou, Guo-Xiang Hao, Efthymios Manolis, Tian-You Wang, Remedios Marques, Valérie Biran, Jumpei Saito, Zheng Guan, Wen-Qi Wang
Publikováno v:
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 2021, 60, pp.1435-1448. ⟨10.1007/s40262-021-01033-x⟩
CLINICAL PHARMACOKINETICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Clinical Pharmacokinetics, 2021, 60, pp.1435-1448. ⟨10.1007/s40262-021-01033-x⟩
CLINICAL PHARMACOKINETICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
International audience; Background Population pharmacokinetic evaluations have been widely used in neonatal pharmacokinetic studies, while machine learning has become a popular approach to solving complex problems in the current era of big data. Obje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59db76eafa7dc3be480fad546acaf27
https://strathprints.strath.ac.uk/77050/1/Tang_etal_CP_2021_Drug_clearance_in_neonates_a_combination_of_population_pharmacokinetic_modelling.pdf
https://strathprints.strath.ac.uk/77050/1/Tang_etal_CP_2021_Drug_clearance_in_neonates_a_combination_of_population_pharmacokinetic_modelling.pdf
Autor:
Rajanikanth Madabushi, Kevin Krudys, Alexander Staab, Scott Marshall, Efthymios Manolis, Sandra A.G. Visser, Kevin Dykstra
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
Good practices around model-informed drug discovery and development (MID3) aim to improve the implementation, standardization, and acceptance of these approaches within drug development and regulatory review. A survey targeted to clinical pharmacolog
Autor:
Raphaëlle Lesage, Flora T. Musuamba, Thierry Marchal, Cécile Crozatier, Jean-Pierre Boissel, Efthymios Manolis, Eulalie Courcelles, Liesbet Geris, Cécile F. Rousseau, Kristin E. Karlsson, Alexander Kulesza, Rossana Alessandrello, Roberta Bursi, Emmanuelle M. Voisin
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 195-197 (2020)
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 195-197 (2020)
The added value of in silico models (including quantitative systems pharmacology models) for drug development is now unanimously recognized. It is, therefore, important that the standards used are commonly acknowledged by all the parties involved. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f6e77d14a3d5b9285f9715027488f5
https://lirias.kuleuven.be/handle/123456789/652695
https://lirias.kuleuven.be/handle/123456789/652695
Autor:
Nicholas H. G. Holford, Joseph F. Standing, Flora T. Musuamba, Norbert Benda, Andrew C. Hooker, Solange Corriol-Rohou, Frank Bretz, P H van der Graaf, Falk Ehmann, Martin Posch, I. Skottheim Rusten, S. Y. A. Cheung, Bjoern Bornkamp, Lena E. Friberg, Kristin E. Karlsson, James W.T. Yates, Robert Hemmings, A. Brochot, Efthymios Manolis, Neal Thomas, Susan Cole, Shampa Das, F. Serone, Valeria Gigante, Scott Berry, Thomas Dumortier, Justin L. Hay, Kayode Ogungbenro
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:418-429
Inadequate dose selection for confirmatory trials is currently still one of the most challenging issues in drug development, as illustrated by high rates of late-stage attritions in clinical development and postmarketing commitments required by regul
Publikováno v:
Clinical pharmacology and therapeutics. 107(4)