Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Efthimia K. Basdra"'
Targeting TLR Signaling Cascades in Systemic Lupus Erythematosus and Rheumatoid Arthritis: An Update
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 138 (2024)
Evidence from animal models and human genetics implicates Toll-like Receptors (TLRs) in the pathogenesis of Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA). Endosomal TLRs sensing nucleic acids were proposed to induce lupus-promoting
Externí odkaz:
https://doaj.org/article/f0fee9a00f4d40208050b4e0b3ac84a6
Autor:
Maria Manou, Theodoros Loupis, Dimitrios M. Vrachnos, Nikolaos Katsoulas, Stamatios Theocharis, Dimitrios S. Kanakoglou, Efthimia K. Basdra, Christina Piperi, Athanasios G. Papavassiliou
Publikováno v:
Cells, Vol 12, Iss 20, p 2437 (2023)
Salivary gland tumors (SGTs) are rare and complex neoplasms characterized by heterogenous histology and clinical behavior as well as resistance to systemic therapy. Tumor etiology is currently under elucidation and an interplay of genetic and epigene
Externí odkaz:
https://doaj.org/article/4aff71e2865a4b648c671899cce45bda
Autor:
Svenja Memmert, Marjan Nokhbehsaim, Anna Damanaki, Andressa V. B. Nogueira, Alexandra K. Papadopoulou, Christina Piperi, Efthimia K. Basdra, Birgit Rath-Deschner, Werner Götz, Joni A. Cirelli, Andreas Jäger, James Deschner
Publikováno v:
BMC Oral Health, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Cathepsin S is a cysteine protease, which is expressed in human periodontal ligament (PDL) cells under inflammatory and infectious conditions. This in vitro study was established to investigate the effect of cathepsin S on PDL cel
Externí odkaz:
https://doaj.org/article/1c0f6eed3be84bb89818b3f1a7b326a1
Autor:
Efthimia K. Basdra, Marios Themistocleous, Ilianna Zoi, Antonios N. Gargalionis, Kostas A. Papavassiliou, Maira Katsianou, Christina Piperi, Athanasios G. Papavassiliou, Dimitrios Panagopoulos
Publikováno v:
Journal of Cellular and Molecular Medicine
Craniosynostosis refers to the premature fusion of one or more cranial sutures leading to skull shape deformities and brain growth restriction. Among the many factors that contribute to abnormal suture fusion, mechanical forces seem to play a major r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b16fa7bf205615d2c8f21217067821
http://europepmc.org/articles/PMC8034462
http://europepmc.org/articles/PMC8034462
Autor:
Maria A. Katsianou, Kostas A. Papavassiliou, Antonios N. Gargalionis, George Agrogiannis, Penelope Korkolopoulou, Dimitrios Panagopoulos, Marios S. Themistocleous, Christina Piperi, Efthimia K. Basdra, Athanasios G. Papavassiliou
Publikováno v:
Journal of cellular and molecular medicine. 26(8)
Craniosynostosis is the premature fusion of skull sutures and has a severe pathological impact on childrens' life. Mechanical forces are capable of triggering biological responses in bone cells and regulate osteoblastogenesis in cranial sutures, lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7b6b1c930b78089c177975b6537362
https://pubmed.ncbi.nlm.nih.gov/35285136
https://pubmed.ncbi.nlm.nih.gov/35285136
Autor:
Antonios N. Gargalionis, Kostas A. Papavassiliou, Efthimia K. Basdra, Athanasios G. Papavassiliou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1825, p 1825 (2022)
Mechanistic target of rapamycin (mTOR) is a central signaling hub that integrates networks of nutrient availability, cellular metabolism, and autophagy in eukaryotic cells. mTOR kinase, along with its upstream regulators and downstream substrates, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c773f9c93dcce87732d5959b5b083d89
https://www.mdpi.com/1422-0067/23/3/1825
https://www.mdpi.com/1422-0067/23/3/1825
Autor:
Ilianna Zoi, Antonios N. Gargalionis, Kostas A. Papavassiliou, Narjes Nasiri‐Ansari, Christina Piperi, Efthimia K. Basdra, Athanasios G. Papavassiliou
Publikováno v:
Journal of cellular and molecular medicine. 26(5)
The mechanobiological aspects of glioblastoma (GBM) pathogenesis are largely unknown. Polycystin-1 (PC1) is a key mechanosensitive protein which perceives extracellular mechanical cues and transforms them into intracellular biochemical signals that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbc01292751325571cf5c45e1875778
https://pubmed.ncbi.nlm.nih.gov/35106909
https://pubmed.ncbi.nlm.nih.gov/35106909
Autor:
Athanasios G. Papavassiliou, Christina Piperi, James Deschner, Anna Damanaki, Efthimia K. Basdra, Sigrun Eick, Marjan Nokhbehsaim, Georgia Dalagiorgou, Andressa Vilas Boas Nogueira, Christos Adamopoulos
Publikováno v:
Clinical Oral Investigations. 24:1987-1995
OBJECTIVES Periodontitis is a highly prevalent chronic inflammatory disease caused by periodontopathogens, such as Filifactor alocis. This study sought to examine the matrix metalloproteinase (MMP)-1 synthesis by monocytic and fibroblastic cells in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b4f3d6baa9fefa9ec8cfca9b83104e
https://doi.org/10.1007/s00784-019-03062-0
https://doi.org/10.1007/s00784-019-03062-0
Autor:
Athanasios G. Papavassiliou, Efthimia K. Basdra, Dimitrios Strepkos, Mariam Markouli, Christina Piperi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2778, p 2778 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2778, p 2778 (2021)
Tumor aggressiveness and progression is highly dependent on the process of metastasis, regulated by the coordinated interplay of genetic and epigenetic mechanisms. Metastasis involves several steps of epithelial to mesenchymal transition (EMT), anoik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f63cdaa0987d4bcc82bf6b0f14121c
http://europepmc.org/articles/PMC7967218
http://europepmc.org/articles/PMC7967218
Publikováno v:
Journal of Cellular Biochemistry. 120:6894-6898
Distorted mechanotransduction represents the molecular hallmark of disease mechanobiology and is displayed with common features during the development of various pathophysiologies. Polycystins constitute a family of mechanosensitive proteins that fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da3b3a3b38bcc2298d4f129e2a17092
https://doi.org/10.1002/jcb.28127
https://doi.org/10.1002/jcb.28127