Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Efstathios S. Avgoustiniatos"'
Autor:
Efstathios S. Avgoustiniatos, Kate R. Mueller, William E. Scott III, Jennifer P. Kitzmann, Thomas M. Suszynski, Brian E. Perrault, Eric J. Falde, A. N. Balamurugan, Bernhard J. Hering, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
IntroductionConventional culture conditions, such as in T-flasks, require that oxygen diffuse through the medium to reach the islets; in turn, islet surface area density is limited by oxygen availability. To culture a typical clinical islet preparati
Externí odkaz:
https://doaj.org/article/6e961f6e73b748fc88ec72a36aad0d63
Autor:
Samuel A. Einstein, Leah V. Steyn, Bradley P. Weegman, Thomas M. Suszynski, Athanassios Sambanis, Timothy D. O’Brien, Efstathios S. Avgoustiniatos, Meri T. Firpo, Melanie L. Graham, Jody Janecek, Lynn E. Eberly, Michael Garwood, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
IntroductionSubcutaneous macroencapsulation devices circumvent disadvantages of intraportal islet therapy. However, a curative dose of islets within reasonably sized devices requires dense cell packing. We measured internal PO2 of implanted devices,
Externí odkaz:
https://doaj.org/article/4d2c40b1f118487788b0c8b74419747e
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Intraportal islet transplantation (IT) is not widely utilized as a treatment for type 1 diabetes. Oxygenation of the intraportally transplanted islet has not been studied extensively. We present a diffusion-reaction model that predicts the presence o
Externí odkaz:
https://doaj.org/article/2a8e54a51b294e139a6afef704bc3f29
Autor:
Efstathios S. Avgoustiniatos, William E. Scott, Thomas M. Suszynski, Henk-Jan Schuurman, Rebecca A. Nelson, Phillip R. Rozak, Kate R. Mueller, A. N. Balamurugan, Jeffrey D. Ansite, Daniel W. Fraga, Andrew S. Friberg, Gina M. Wildey, Tomohiro Tanaka, Connor A. Lyons, David E. R. Sutherland, Bernhard J. Hering, Klearchos K. Papas Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Culture of human islets before clinical transplantation or distribution for research purposes is standard practice. At the time the Edmonton protocol was introduced, clinical islet manufacturing did not include culture, and human serum albumin (HSA),
Externí odkaz:
https://doaj.org/article/c5e402ec201f479eb0b9e81ede12fbcf
Autor:
Klearchos K Papas, Melena D Bellin, David E R Sutherland, Thomas M Suszynski, Jennifer P Kitzmann, Efstathios S Avgoustiniatos, Angelika C Gruessner, Kathryn R Mueller, Gregory J Beilman, Appakalai N Balamurugan, Gopalakrishnan Loganathan, Clark K Colton, Maria Koulmanda, Gordon C Weir, Josh J Wilhelm, Dajun Qian, Joyce C Niland, Bernhard J Hering
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134428 (2015)
BackgroundReliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular ox
Externí odkaz:
https://doaj.org/article/3b1106a0d9a04b4484572e0579606e02
Publikováno v:
Panminerva medica. 58(1)
Beta-cell replacement therapy is a promising approach for the treatment of diabetes but is currently limited by the human islet availability and by the need for systemic immunosuppression. Tissue engineering approaches that will enable the utilizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adcddceacca18a34fe0826f8644c5cb5
https://pubmed.ncbi.nlm.nih.gov/26837777
https://pubmed.ncbi.nlm.nih.gov/26837777
Autor:
Thomas M, Suszynski, Michael D, Rizzari, Louis S, Kidder, Kate, Mueller, Christopher S, Chapman, Jennifer P, Kitzmann, Rebecca L, Pongratz, Gary W, Cline, Paul W, Todd, David J, Kennedy, Timothy D, O'Brien, Efstathios S, Avgoustiniatos, Henk-Jan, Schuurman, Klearchos K, Papas
Publikováno v:
Xenotransplantation. 18(4)
Paramagnetic microparticles (MPs) may be useful in pancreatic islet purification, in particular purification of porcine islets as a potential xenotransplantation product. We assessed whether MPs affect islet function or induce an adverse effect follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cea25b7476ad990ff4aab8e897a0f1c
https://pubmed.ncbi.nlm.nih.gov/21848541
https://pubmed.ncbi.nlm.nih.gov/21848541
Autor:
Patrick Aebischer, Richard A. Altschuler, Pascal Ambrosini, David J. Anderson, Anthony Atala, François A. Auger, Efstathios S. Avgoustiniatos, David W. Barnes, Eugene Bell, Marie C. Béné, John G. Bishop, T. Bohrer, Lawrence J. Bonassar, Amy D. Bradshaw, Kelvin G.M. Brockbank, Leon W. Browder, Scott P. Bruder, Mary Bartlett Bunge, Arnold I. Caplan, Thomas Ming Swi Chang, Robert G. Chapman, Una Chen, Richard A.F. Clark, Réjean Cloutier, Clark K. Colton, Joanne C. Cousins, Stephen C. Cowin, Gislin Dagnelie, Thomas F. Deuel, Charles N. Durfor, Brian E. Edwards, Carol A. Erickson, Gilbert C. Faure, Denise Faustman, Dario O. Fauza, Eric G. Fine, Lee G. Fradkin, Lisa E. Freed, Claudia Gaffey, John D. Gearhart, Lucie Germain, Francine Goulet, Howard P. Greisler, Alan J. Grodzinsky, Craig R. Halberstadt, Janet Hardin-Young, C. Hasse, Matthias Hebrok, Kiki B. Hellman, Walter D. Holder, Edward Hsu, Jeffrey A. Hubbell, Mark S. Humayun, H. David Humes, Donald E. Ingber, Hugo O. Jauregui, Roger D. Kamm, Ravi S. Kane, Jens O.M. Karlsson, Anne Kessinger, Byung-Soo Kim, Naomi Kleitman, Joachim Kohn, Hiroshi Kubota, Robert P. Lanza, Douglas A. Lauffenburger, Kuen Yong Lee, Peter I. Lelkes, Robert E. London, Jack W. Love, Thomas L. Luntz, Michael J. Lysaght, Jeffrey M. Macdonald, Manuela Martins-Green, Robert W. Massof, John M. McPherson, Douglas A. Melton, Antonios G. Mikos, Josef M. Miller, Neal A. Miller, David J. Mooney, Jennifer E. Morgan, Melvin L. Moss, Claudy Mullon, Christopher S. Muratore, Gail K. Naughton, Robert M. Nerem, Björn Reino Olsen, Gregory M. Organ, James M. Pachence, Nancy L. Parenteau, Terence A. Partridge, Jacques Penaud, A. Robin Poole, Denis Rancourt, Yehoash Raphael, A.H. Reddi, Lola M. Reid, J. Dezz Ropp, Robert N. Ross, M. Rothmund, R. Bruce Rutherford, E. Helene Sage, Jacqueline Sagen, W. Mark Saltzman, Gordon H. Sato, Jochen Schacht, Michael J. Shamblott, Graham Sharp, Albert K. Shung, Adam J. Singer, Barry A. Solomon, Ruth R. Solomon, Susan J. Sullivan, Shuichi Takayama, Jeffrey Teumer, Robert C. Thomson, Mehmet Toner, Vickery Trinkaus-Randall, Ross Tubo, Brian R. Unsworth, Charles A. Vacanti, Joseph P. Vacanti, Martin P. Vacanti, Robert F. Valentini, Gordana Vunjak-Novakovic, Lars U. Wahlberg, Taylor G. Wang, John F. Warner, George M. Whitesides, Jay M. Wilson, Haiyun Wu, Arron S.L. Xu, Lian Xue, Ioannis V. Yannas, Michael J. Yaszemski, Nan Zhang, Beth A. Zielinski, A. Zielke, U. Zimmerman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29045b09162a51ba8a261d09baa1b169
https://doi.org/10.1016/b978-012436630-5/50000-3
https://doi.org/10.1016/b978-012436630-5/50000-3
Autor:
Efstathios S. Avgoustiniatos, Keith E. Dionne, David F. Wilson, Martin L. Yarmush, Clark K. Colton
Publikováno v:
Industrial & Engineering Chemistry Research; Sep2007, Vol. 46 Issue 19, p6157-6163, 7p