Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Efrosyni, Paraskeva"'
Autor:
Angelos Yfantis, Ilias Mylonis, Georgia Chachami, Marios Nikolaidis, Grigorios D. Amoutzias, Efrosyni Paraskeva, George Simos
Publikováno v:
Cells, Vol 12, Iss 5, p 798 (2023)
The Hypoxia Inducible Factor 1 (HIF-1) plays a major role in the cellular response to hypoxia by regulating the expression of many genes involved in adaptive processes that allow cell survival under low oxygen conditions. Adaptation to the hypoxic tu
Externí odkaz:
https://doaj.org/article/6ab1181c8ed842868f85a0a7a71d80e0
Autor:
Antonis E. Koromilas, George Simos, Kostas Pantopoulos, Leda Raptis, Suiyang Li, Hala Muaddi, Philippos Peidis, Efrosyni Paraskeva, Andreas I. Papadakis
Hypoxia within the tumor microenvironment promotes angiogenesis, metabolic reprogramming, and tumor progression. In addition to activating hypoxia-inducible factor-1α (HIF-1α), cells also respond to hypoxia by globally inhibiting protein synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57156bbabc712aa29041c821dad319b9
https://doi.org/10.1158/0008-5472.c.6501158.v1
https://doi.org/10.1158/0008-5472.c.6501158.v1
Autor:
Antonis E. Koromilas, George Simos, Kostas Pantopoulos, Leda Raptis, Suiyang Li, Hala Muaddi, Philippos Peidis, Efrosyni Paraskeva, Andreas I. Papadakis
Supplementary Figures 1-6 from eIF2α Kinase PKR Modulates the Hypoxic Response by Stat3-Dependent Transcriptional Suppression of HIF-1α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47573ca9101fac0210e6bb2ea7403d9
https://doi.org/10.1158/0008-5472.22385231
https://doi.org/10.1158/0008-5472.22385231
Publikováno v:
Cells, Vol 8, Iss 3, p 214 (2019)
Oxygen deprivation or hypoxia characterizes a number of serious pathological conditions and elicits a number of adaptive changes that are mainly mediated at the transcriptional level by the family of hypoxia-inducible factors (HIFs). The HIF target g
Externí odkaz:
https://doaj.org/article/9ce226a01f9342c79066f50890c4e9bb
Publikováno v:
Cancers
Cancers, Vol 14, Iss 228, p 228 (2022)
Cancers, Vol 14, Iss 228, p 228 (2022)
Simple Summary Rapidly proliferating cancer cells reprogram lipid metabolism to keep the balance between fatty acid uptake, synthesis, consumption, and storage as triacylglycerides (TAG). Acylglycerolphosphate acyltransferases (AGPATs)/lysophosphatid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55190512823ff72ecff8bc397ea57542
http://europepmc.org/articles/PMC8750616
http://europepmc.org/articles/PMC8750616
Autor:
Eleni Karetsi, Maria G. Ioannou, Theodora Kerenidi, Markos Minas, Paschalis A. Molyvdas, Konstantinos I. Gourgoulianis, Efrosyni Paraskeva
Publikováno v:
Clinics, Vol 67, Iss 12, Pp 1373-1378 (2012)
OBJECTIVES: The aim of this study was to compare the expression of hypoxia-inducible factor 1α and vascular endothelial growth factor in small cell lung cancer and subtypes of non-small cell lung cancer and examine their relationships with clinicopa
Externí odkaz:
https://doaj.org/article/e1053b17f0d64c1eb92c71384831bd9d
Publikováno v:
Hypoxia
Hypoxia and its key mediators hypoxia inducible Factors (HIFs) are implicated in the development of liver diseases of diverse etiologies, often in interplay with inflammatory mediators. We investigated the interplay between hypoxia and proinflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef932a10b4a6b65e543bce8d5fcb25d
http://europepmc.org/articles/PMC6935274
http://europepmc.org/articles/PMC6935274
Autor:
Ilias Mylonis, Efrosyni Paraskeva, George Simos, Eleni Georgatsou, Eleni-Anastasia Triantafyllou
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1863(9)
Hypoxia inducible factor-1 (HIF-1) supports survival of normal cells under low oxygen concentration and cancer cells in the hypoxic tumor microenvironment. This involves metabolic reprogramming via upregulation of glycolysis, downregulation of oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf3f110fc77a18382508aadd0d510ac
https://pubmed.ncbi.nlm.nih.gov/29908837
https://pubmed.ncbi.nlm.nih.gov/29908837
Autor:
George Simos, Georgia Chachami, Efrosyni Paraskeva, Kostas Pantopoulos, Aggeliki Lyberopoulou, Alkmini Kalousi
Publikováno v:
Biochemical and Biophysical Research Communications. 435:540-545
Hepcidin, a hepatic hormone, regulates serum iron levels by controlling both intestinal iron absorption and iron release from macrophages. Although transcription of hepcidin is controlled by diverse stimuli, it remains elusive if post-transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c710cd2650e35ff79eb30fa561b1e6
https://doi.org/10.1016/j.bbrc.2013.04.085
https://doi.org/10.1016/j.bbrc.2013.04.085
Autor:
Paschalis-Adam Molyvdas, Georgios K. Koukoulis, Rodopi Stamatiou, George Simos, Stamatina Tsapournioti, Apostolia Hatziefthimiou, Maria Ioannou, Ilias Mylonis, Efrosyni Paraskeva
Publikováno v:
Journal of Cellular Physiology. 228:1745-1753
Airway smooth muscle cells (ASMCs) participate in tissue remodeling characteristic of airway inflammatory diseases like asthma. Inflammation and hypoxia pathways are often interconnected and the regulatory subunit of the hypoxia inducible factor, HIF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::107b35c536741e1b830cadc122831742
https://doi.org/10.1002/jcp.24331
https://doi.org/10.1002/jcp.24331