Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Efrat Merhavi-Shoham"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Targeting epitopes derived from neo-antigens (or “neo-epitopes”) represents a promising immunotherapy approach with limited off-target effects. However, most peptides predicted using MHC binding prediction algorithms do not in
Externí odkaz:
https://doaj.org/article/93412e43cde04b1286320e9a879e56ca
Autor:
Sivan Seliktar-Ofir, Efrat Merhavi-Shoham, Orit Itzhaki, Sharon Yunger, Gal Markel, Jacob Schachter, Michal J. Besser
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Adoptive cell therapy (ACT) of autologous tumor infiltrating lymphocytes (TIL) is an effective immunotherapy for patients with solid tumors, yielding objective response rates of around 40% in refractory patients with metastatic melanoma. Most clinica
Externí odkaz:
https://doaj.org/article/d7d294fb92b74aa58b01f05c3cb0fbea
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Targeting epitopes derived from neo-antigens (or “neo-epitopes”) represents a promising immunotherapy approach with limited off-target effects. However, most peptides predicted using MHC binding prediction algorithms do not induce a CD8 + T cell
Publikováno v:
The Cancer Journal. 23:48-53
Adoptive cell therapy (ACT) of tumor-infiltrating lymphocytes (TILs) is a powerful form of immunotherapy by inducing durable complete responses that significantly extend the survival of melanoma patients. Mutation-derived neoantigens were recently id
Autor:
Eilon Barnea, Shelly Kalaora, Nilly Shimony, Jacob Schachter, Yardena Samuels, Steven A. Rosenberg, Efrat Merhavi-Shoham, Michal J. Besser, Jamie K. Teer, Arie Admon, Nouar Qutob
Publikováno v:
Oncotarget
// Shelly Kalaora 1 , Eilon Barnea 2,* , Efrat Merhavi-Shoham 3,* , Nouar Qutob 1 , Jamie K. Teer 4 , Nilly Shimony 3 , Jacob Schachter 3 , Steven A. Rosenberg 5 , Michal J. Besser 3,6,** , Arie Admon 2,** and Yardena Samuels 1 1 Department of Molecu
Autor:
Michael Savetsky, Yoram Cohen, Efrat Merhavi-Shoham, Jacob Pe'er, Shahar Frenkel, Nitza Goldenberg-Cohen, Bat Chen R. Avraham-Lubin
Publikováno v:
Investigative ophthalmologyvisual science. 50(11)
PURPOSE. Many malignancies are known to be associated with abnormal activation of the PI3K-AKT pathway. Recently, a somatic mutation in the AKT1 gene (E17K) was identified in a small proportion of human tumors. This mutation activated AKT1 by means o
Autor:
Revital B. Avraham, Shahar Frenkel, Efrat Merhavi-Shoham, Jacob Pe'er, Nitza Goldenberg-Cohen, Yoram Cohen
Publikováno v:
Experimental eye research. 86(2)
Epigenetic silencing of tumor suppressor genes by methylation of discrete regions of the CpG islands is a major mechanism underlying tumorigenesis. Methylation of at least three of five specific genes may represent a distinct trait, termed the CpG is
Autor:
Shimrit Dadon-Bar El, Nitza Goldenberg-Cohen, Yoram Cohen, Olga Dratviman-Storobinsky, Natalia Binkovsky, Efrat Merhavi-Shoham, Jacob Pe'er, Shahar Frenkel
Publikováno v:
Investigative Opthalmology & Visual Science. 53:2611
PURPOSE RASSF1A inactivation in uveal melanoma (UM) is common and methylation-induced. We investigated the effect of RASSF1A re-expression on the UM phenotype in vivo and in vitro. METHODS The phenotypic effect of methylation-induced inactivation of