Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Effie E, Bastounis"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101832- (2022)
Summary: Cell motility and biomechanics are critical in various (patho)physiological processes, including the regulation of vascular barrier integrity, which can be subverted by bacterial pathogens. Here, we present a protocol on how to expose endoth
Externí odkaz:
https://doaj.org/article/067a329ecc0f4280ab6dc7139a81033b
Autor:
Raúl Aparicio Yuste, Marie Muenkel, Konstantinos Axarlis, María J. Gómez Benito, Annalena Reuss, Grace Blacker, Michal Caspi Tal, Peter Kraiczy, Effie E. Bastounis
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104793- (2022)
Summary: Borrelia burgdorferi (Bb), a vector-borne bacterial pathogen and the causative agent of Lyme disease, can spread to distant tissues in the human host by traveling in and through monolayers of endothelial cells (ECs) lining the vasculature. T
Externí odkaz:
https://doaj.org/article/53a6bebb630d447588f4790ec2498c2c
Autor:
Raúl Aparicio-Yuste, Marie Muenkel, Andrew G. Clark, María J. Gómez-Benito, Effie E. Bastounis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cell competition refers to the mechanism whereby less fit cells (“losers”) are sensed and eliminated by more fit neighboring cells (“winners”) and arises during many processes including intracellular bacterial infection. Extracellular matrix
Externí odkaz:
https://doaj.org/article/271514df041045f8802c46493acb385f
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100551- (2021)
Summary: Mechanical forces are important in (patho)physiological processes, including how host epithelial cells interact with intracellular bacterial pathogens. As these pathogens disseminate within host epithelial monolayers, large mounds of infecte
Externí odkaz:
https://doaj.org/article/9fdf6d6eddf54390b32eec09100508cb
Publikováno v:
Advanced Healthcare Materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e79ce6a3488cb27f73e89899812fe10
https://doi.org/10.1002/adhm.202203256
https://doi.org/10.1002/adhm.202203256
Publikováno v:
Trends in Biotechnology.
Basic human functions such as breathing and digestion require mechanical stretching of cells and tissues. However, when it comes to laboratory experiments, the mechanical stretching that cells experience in the body is not often replicated, limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e54550665e1273c110315d5c14460f2
https://doi.org/10.1016/j.tibtech.2022.12.009
https://doi.org/10.1016/j.tibtech.2022.12.009
Autor:
Cristina Faralla, Effie E Bastounis, Fabian E Ortega, Samuel H Light, Gabrielle Rizzuto, Lei Gao, Denise K Marciano, Salvatore Nocadello, Wayne F Anderson, Jennifer R Robbins, Julie A Theriot, Anna I Bakardjiev
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007094 (2018)
During pregnancy, the placenta protects the fetus against the maternal immune response, as well as bacterial and viral pathogens. Bacterial pathogens that have evolved specific mechanisms of breaching this barrier, such as Listeria monocytogenes, pre
Externí odkaz:
https://doaj.org/article/145df8a400814774821df311810559de
Publikováno v:
Microbiol Mol Biol Rev
To combat infectious diseases, it is important to understand how host cells interact with bacterial pathogens. Signals conveyed from pathogen to host, and vice versa, may be either chemical or mechanical. While the molecular and biochemical basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481e0fc45d94abdf79564151b8046154
https://doi.org/10.1128/mmbr.00094-20
https://doi.org/10.1128/mmbr.00094-20
Autor:
Shaghayegh, Jahanbani, Paige S, Hansen, Lisa K, Blum, Effie E, Bastounis, Nitya S, Ramadoss, Mallesh, Pandrala, Jessica Marie, Kirschmann, Grace Sisemore, Blacker, Zelda Z, Love, Irving L, Weissman, Fahimeh, Nemati, Michal Caspi, Tal, William H, Robinson
Publikováno v:
Clinical Immunology. 246:109180
Borrelia burgdorferi (Bb) infection causes Lyme disease, for which there is need for more effective therapies. Here, we sequenced the antibody repertoire of plasmablasts in Bb-infected humans. We expressed recombinant monoclonal antibodies (mAbs) rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0204a0507ece940bc600dd481b31796c
https://doi.org/10.1016/j.clim.2022.109180
https://doi.org/10.1016/j.clim.2022.109180
Autor:
Raul Aparicio-Yuste, Francisco Serrano-Alcalde, Marie Muenkel, Jose Manuel Garcia-Aznar, Effie E. Bastounis, Maria Jose Gomez-Benito
Publikováno v:
Computer Methods in Applied Mechanics and Engineering. 401:115477
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3ac7a57da0314fe6e78a202813851d4
https://doi.org/10.1016/j.cma.2022.115477
https://doi.org/10.1016/j.cma.2022.115477