Non-steroidal anti-inflammatory drugs for acute gout

Autor: Caroline MPG van Durme, Mihir D Wechalekar, Robert BM Landewé, Jordi Pardo Pardo, Sheila Cyril, Désirée van der Heijde, Rachelle Buchbinder

Publikováno v: Cochrane Database Syst Rev
Cochrane Database of Systematic Reviews
ISSUE=9;TITLE=Cochrane Database of Systematic Reviews
The Cochrane Library

Background Gout is an inflammatory arthritis that is characterised by the deposition of monosodium urate crystals in synovial fluid and other tissues. The natural history of articular gout is generally characterised by three periods: asymptomatic hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acac3e103b24c829609699c9c893ad2e
https://doi.org/10.1002/14651858.cd010120.pub3

Evaluation of Macitentan in Patients With Eisenmenger Syndrome Results From the Randomized, Controlled MAESTRO Study

Autor: Gatzoulis, Michael A, Landzberg, Michael, Beghetti, Maurice, Berger, Rolf M, Efficace, Michela, Gesang, Sophie, He, Jian'guo, Papadakis, Kelly, Pulido, Tomás, Galiè, Nazzareno, MAESTRO Study Investigators

Publikováno v: Circulation, 139(1), 51-63. LIPPINCOTT WILLIAMS & WILKINS
Circulation, Vol. 139, No 1 (2019) pp. 51-63

Background: Eisenmenger syndrome describes congenital heart disease-associated severe pulmonary hypertension accompanied by right-to-left shunting. The multicenter, double-blind, randomized, placebo-controlled, 16-week, phase III MAESTRO study (Macit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed441d34aa3a8f7a94367cf4a62011fb
https://doi.org/10.1161/circulationaha.118.033575

Non-steroidal anti-inflammatory drugs for acute gout

Publikováno v: Cochrane Database of Systematic Reviews. (12)

BackgroundGout is an inflammatory arthritis resulting from the deposition of monosodium urate crystals in and around joints. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat acute gout. This is an update of a Cochrane Review

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od________83::afb8ec85b609234330f2cfee6b7f5b5e
https://doi.org/10.1002/14651858.CD010120.pub3

Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium

Autor: Jae-Gook Shin, Dan M. Roden, Stefan Winter, Paul A. Gurbel, Michiaki Kubo, Braxton D. Mitchell, Joshua P. Lewis, Yuki Bradford, Daniel Aradi, Kevin P. Bliden, Jurriën M. ten Berg, Thomas O. Bergmeijer, Kiyuk Chang, Ruth E. Pakyz, Alan R. Shuldiner, Ho-Sook Kim, Jean-Luc Reny, Meinrad Gawaz, Tobias Geisler, Gianluca Campo, Marco Valgimigli, Elke Schaeffeler, Jolanta M. Siller-Matula, Gian Franco Gensini, Lene Holmvang, Willibald Hochholzer, Rossella Marcucci, Betti Giusti, Ming Ta Michael Lee, Jean-Pierre Déry, Dietmar Trenk, Ming-Shien Wen, John M. Wallace, Marylyn D. Ritchie, Teri E. Klein, Israel Fernandez-Cadenas, Dimitrios Alexopoulos, Matthias Schwab, Ryan Whaley, John H. Cleator, Pierre Fontana, Joshua D. Backman, Russ B. Altman, Shefali S. Verma, Eun Young Kim, Nadia Paarup Dridi, Li Gong, Joan Montaner

Publikováno v: Clinical Pharmacology & Therapeutics
Clinical Pharmacology and Therapeutics
Verma, S S, Bergmeijer, T O, Gong, L, Reny, J L, Lewis, J P, Mitchell, B D, Alexopoulos, D, Aradi, D, Altman, R B, Bliden, K, Bradford, Y, Campo, G, Chang, K, Cleator, J H, Déry, J P, Dridi, N P, Fernandez-Cadenas, I, Fontana, P, Gawaz, M, Geisler, T, Gensini, G F, Giusti, B, Gurbel, P A, Hochholzer, W, Holmvang, L, Kim, E Y, Kim, H S, Marcucci, R, Montaner, J, Backman, J D, Pakyz, R E, Roden, D M, Schaeffeler, E, Schwab, M, Shin, J G, Siller-Matula, J M, ten Berg, J M, Trenk, D, Valgimigli, M, Wallace, J, Wen, M S, Kubo, M, Lee, M T M, Whaley, R, Winter, S, Klein, T E, Shuldiner, A R, Ritchie, M D & for the ICPC Investigators 2020, ' Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel : A Study by the International Clopidogrel Pharmacogenomics Consortium ', Clinical Pharmacology and Therapeutics, vol. 108, no. 5, pp. 1067-1077 . https://doi.org/10.1002/cpt.1911
Clinical Pharmacology and Therapeutics, Vol. 108, No 5 (2020) pp. 1067-1077

Antiplatelet response to clopidogrel shows wide variation, and poor response is correlated with adverse clinical outcomes. CYP2C19 loss-of-function alleles play an important role in this response, but account for only a small proportion of variabilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879ba4faf94686e3e39457e594e198cf
http://hdl.handle.net/11392/2437791

Citicoline for treating people with acute ischemic stroke (Review)

Autor: Martí-Carvajal, A.J., Valli, C., Martí-Amarista, C.E., Solà, I., Martí-Fàbregas, J., Bonfill Cosp, X.

Publikováno v: DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Universitat Autònoma de Barcelona

Background Stroke is one of the leading causes of long‐lasting disability and mortality and its global burden has increased in the past two decades. Several therapies have been proposed for the recovery from, and treatment of, ischemic stroke. One

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4fe00d97845de28412fb5816ad29c806
https://hdl.handle.net/10641/2399