Zobrazeno 1 - 10
of 1 644
pro vyhledávání: '"Effector cells"'
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 6, Pp 426-431 (2024)
ObjectiveTo explore the significance of the combined strategy of oncolytic virus infection, immune effector cell supplement, and immune checkpoint blocking in the treatment of gastric cancer. MethodsA tumor-bearing nude mouse model of gastric cancer
Externí odkaz:
https://doaj.org/article/f9618f1a33464605aae3172db47ba2ec
Publikováno v:
Mathematical Biosciences and Engineering, Vol 21, Iss 5, Pp 5900-5946 (2024)
Resistance to treatment poses a major challenge for cancer therapy, and oncoviral treatment encounters the issue of viral resistance as well. In this investigation, we introduce deterministic differential equation models to explore the effect of resi
Externí odkaz:
https://doaj.org/article/d3ffc7a5dadd448ebf3f7cec260a1059
Autor:
V. A. Kozlov
Publikováno v:
Медицинская иммунология, Vol 26, Iss 2, Pp 231-236 (2024)
The ageing process should be considered with respect to all homeostatic systems of the body, their importance for the existence of the organism itself and different timing of their switching-on in the process of age-related changes. An attention shou
Externí odkaz:
https://doaj.org/article/cf4eb9d5a8c94c47b1a7aba576f82368
Publikováno v:
Vaccines, Vol 12, Iss 8, p 867 (2024)
Numerous factors influence the magnitude and effector phenotype of vaccine-induced CD8+ T cells, thereby potentially impacting treatment efficacy. Here, we investigate the effect of vaccination dose, route of immunization, presence of a target antige
Externí odkaz:
https://doaj.org/article/26b45fe198a34fc78933cba24f6f2404
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f5eec702536d4055acd9fc215f0473d7
Autor:
Marco Aurelio Salvino, Alberto Mussetti, Marta Peña, Annalisa Paviglianiti, Abel Santos Carreira, Daniel Rizky, Anna Sureda
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
Cell therapy, specifically the revolutionary chimeric antigen receptor (CAR) T-cell therapy, has transformed the landscape of oncology, making substantial strides in practical treatment approaches. Today, established guidelines for diseases such as l
Externí odkaz:
https://doaj.org/article/f4397de0f82a44eeaeb1a0d77f62d805
Autor:
Manuela Giansanti, Tobias Theinert, Sarah Katharina Boeing, Dorothee Haas, Paul-Gerhardt Schlegel, Paola Vacca, Francesca Nazio, Ignazio Caruana
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-26 (2023)
Abstract Autophagy is an essential cellular homeostasis pathway initiated by multiple stimuli ranging from nutrient deprivation to viral infection, playing a key role in human health and disease. At present, a growing number of evidence suggests a ro
Externí odkaz:
https://doaj.org/article/dda7511bdfcc402497479b670edc5983
Autor:
Dilixiati Tuerdimaimaiti, Buzukela Abuduaini, Shaotao Kang, Jinliang Jiao, Mengchen Li, Wolazihan Madeniyati, Baihetinisha Tuerdi, Gulisitan Aili, Reyila Tuerhong, Ajiguli Kulaxi
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background An increasing body of evidence now shows that the long-term mortality of patients with sepsis are associated with various sepsis-related immune cell defects. Alternative splicing (AS), as a sepsis-related immune cell defect, is co
Externí odkaz:
https://doaj.org/article/53bce1f7abc3409385238a571dfad904
Akademický článek
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Autor:
Craig M. Rive, Eric Yung, Lisa Dreolini, Scott D. Brown, Christopher G. May, Daniel J. Woodsworth, Robert A. Holt
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 4-14 (2022)
Anti-CD19 chimeric antigen receptor (CAR)-T therapy for B cell malignancies has shown clinical success, but a major limitation is the logistical complexity and high cost of manufacturing autologous cell products. If engineered for improved safety, di
Externí odkaz:
https://doaj.org/article/e9e2841271204775972c31c9bc2c6647