Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Effector T-Lymphocyte"'
Autor:
Pei Jinpeng, Ker Yu, Jin Rui, Zhiqiang Ren, Xin Wang, Yun Xing, Lanping Ma, Liang Liu, Xuesai Zhang, Jingkang Shen, Ying Cong, Tao Meng
Publikováno v:
Molecular cancer therapeutics. 19(11)
Although tyrosine kinase inhibitor therapy and immunotherapy have significantly improved lung cancer management, many patients do not benefit or become resistant to treatment, highlighting the need for novel treatments. We found elevated CD73 express
Autor:
Nouhoum Sako, Valérie Molinier-Frenkel, Flavia Castellano, Aude Aubatin, Xavier Decrouy, Emmanuel Donnadieu
Publikováno v:
European Journal of Immunology. 48:106-119
Amino-acid catabolizing enzymes produced by mononuclear phagocytes play a central role in regulating the immune response. The mammalian phenylalanine-catabolizing enzyme IL4-induced gene 1 (IL4I1) inhibits effector T lymphocyte proliferation and faci
Autor:
Kentaro Inamura, Yasuyuki Shigematsu
Publikováno v:
Hepatobiliary surgery and nutrition. 7(6)
Immune checkpoint inhibitors (ICIs) have revolutionized the therapeutic approaches used to treat cancer. Immune checkpoint molecules located on tumor cells interact with receptors on cytotoxic CD8+ T cells (a type of effector T lymphocyte) and conseq
Autor:
Régnier, Paul
Publikováno v:
Immunologie. Université Sorbonne Paris Cité, 2018. Français. ⟨NNT : 2018USPCB133⟩
The cancer, one of the main causes of death in the world, can appear in almost any type of tissue, and is characterized by an anarchic proliferation of cells and the establishment of a tolerogenic immune response favouring the tumour growth, leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b275e8a37194b5b5eb7b1d3518ea3c04
https://tel.archives-ouvertes.fr/tel-03411100
https://tel.archives-ouvertes.fr/tel-03411100
Autor:
Régnier, Paul
Publikováno v:
Immunologie. Université Sorbonne Paris Cité, 2018. Français. ⟨NNT : 2018USPCB133⟩
The cancer, one of the main causes of death in the world, can appear in almost any type of tissue, and is characterized by an anarchic proliferation of cells and the establishment of a tolerogenic immune response favouring the tumour growth, leading
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::b275e8a37194b5b5eb7b1d3518ea3c04
https://theses.hal.science/tel-03411100/file/va_Regnier_Paul.pdf
https://theses.hal.science/tel-03411100/file/va_Regnier_Paul.pdf
Autor:
Matthias Kreuzaler, Min Lu, Stephanie Darbre, Alfred Zippelius, Daniel D. Pinschewer, Mario Kreutzfeldt, Philipp Müller, Nicolas Page, Weldy V. Bonilla, Stéphanie Favre, Sandra M. Kallert, Max Löhning, Sanjiv A. Luther, Doron Merkler, Florian Kreppel
Publikováno v:
Nature Communications, Vol. 8 (2017) P. 15327
Nature Communications
Nature communications, vol. 8, pp. 15327
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature communications, vol. 8, pp. 15327
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Viral infections lead to alarmin release and elicit potent cytotoxic effector T lymphocyte (CTLeff) responses. Conversely, the induction of protective tumour-specific CTLeff and their recruitment into the tumour remain challenging tasks. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cecd39857413817068e6b7d5865400
https://archive-ouverte.unige.ch/unige:98397
https://archive-ouverte.unige.ch/unige:98397
Effector T lymphocytes need to efficiently navigate through complex and diverse microenvironments to reach the site of tissue injury, where they exert their effector functions. To do so, T cells employ a wide range of cell-intrinsically regulated mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::662e019f53f56937b9c98814a1bda1c8
https://doi.org/10.1016/b978-0-12-374279-7.07014-4
https://doi.org/10.1016/b978-0-12-374279-7.07014-4
Publikováno v:
The Journal of Immunology. 182:6508-6516
An important regulatory suppressive function in autoimmune and other inflammatory processes has been ascribed to CD4+Foxp3+ regulatory T cells (Tregs), which requires direct cell-cell communication between Tregs, effector T cells, and APCs. However,
Autor:
Lixin Zheng, Alan Sher, Jennifer L. Cannons, Dragana Jankovic, Damien Chaussabel, Pamela L. Schwartzberg, Patricia Caspar, Wendy T. Watford, Michael J. Lenardo, Carl G. Feng, Sara Hieny, André Báfica
Publikováno v:
Nature Immunology. 9:1279-1287
Mice deficient in the interferon-gamma (IFN-gamma)-inducible, immunity-related GTPase Irgm1 have defective host resistance to a variety of intracellular pathogens. This greater susceptibility to infection is associated with impaired IFN-gamma-depende