Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Eeva-Liisa Appelkvist"'
Autor:
Lars Hagenfeldt, Nikolaos Venizelos, Yiyi Zhang, Gustav Dallner, Eeva-Liisa Appelkvist, Ingela Parmryd
Publikováno v:
Pediatric Research. 46:345-350
Fibroblasts were cultured to determine the involvement of peroxisomes in cholesterol and dolichol synthesis. For this purpose, the behavior of cells from patients with Zellweger syndrome, with X-linked adrenoleukodystrophy, and from nondiseased contr
Autor:
Paul Hjemdahl, Bo Angelin, Eeva-Liisa Appelkvist, Anders Bröijersén, M. Eriksson, Gustav Dallner, F Aberg
Publikováno v:
European Journal of Clinical Investigation. 28:235-242
BACKGROUND Low blood levels of antioxidants are associated with an increased risk of developing coronary artery disease. Lipophilic antioxidants are transported in lipoproteins, and hypolipidaemic therapy may therefore alter their blood concentration
Publikováno v:
Chemico-Biological Interactions. 99:205-218
Rats were treated with various peroxisome proliferators and concomitant changes in ubiquinone levels were monitored. In addition to clofibrate and di(2-ethylhexyl)phthalate, acetylsalicylic acid, 2-ethylhexanoic acid, thyroxine and dehydroepiandroste
Publikováno v:
Journal of Biochemical Toxicology. 10:87-94
The peroxisome proliferators perfluorooctanoic acid (PFOA; 0.02% w/w), perfluorodecanoic acid (PFDA; 0.02%, w/w), nafenopin (0.125%, w/w), clofibrate (0.5%, w/w), and acetylsalicylic acid (ASA; 1%, w/w) were administered to male C57 BL/6 mice in thei
Autor:
Eeva-Liisa Appelkvist, Fredrik Åberg
Publikováno v:
Acta Biochimica Polonica. 41:321-329
Induction studies were performed on liver, muscle, heart, brain and blood by feeding Sprague-Dawley rats a diet containing a peroxisome proliferator, clofibrate or di(2-ethylhexyl)phthalate. Ingestion of these drugs resulted in an increase in the amo
Publikováno v:
Environmental Health Perspectives
With the aid of immunohistochemical methods the localization of the various isoenzymes of glutathione S-transferase was investigated. The alpha isoenzyme was present solely in the proximal tubular cells of the human kidney, while the pi form was rest
Publikováno v:
Molecular Aspects of Medicine. 15:s37-s46
The side-chain moiety of coenzyme Q is synthesized by a trans-prenyltransferase present in microsomes. Condensation of this moiety with the precursor ring takes place in the Golgi system. The enzymes involved, as well as the cytosolic geranylgeranyl-
Publikováno v:
Pharmacology & Toxicology. 72:321-331
The distribution of alpha and pi class glutathione transferases in autopsy and biopsy samples of normal human tissues was investigated by immunohistochemistry. The class alpha glutathione transferases exhibited restricted distribution. Intensive stai
Publikováno v:
Archives of Biochemistry and Biophysics. 295:230-234
The distribution and redox state of ubiquinone in rat and human tissues have been investigated. A rapid extraction procedure and direct injection onto HPLC were employed. It was found in model experiments that in postmortem tissue neither oxidation n
Publikováno v:
Archives of Biochemistry and Biophysics. 282:318-325
Cholesterol biosynthesis by isolated rat liver peroxisomes was examined. Labeling of cholesterol from [3H]-mevalonate in the presence of peroxisomes required the addition of cytosol, since peroxisomes, like microsomes, apparently possess only those e