Výsledky vyhledávání - "Eeva Rouvinen"

Plasma Metabolomic Profile of Human Brain-Dead Organ Donors

Autor: T. Suominen, V. Velagapudi, S. Joo, Karl B. Lemström, Kishor Dhaygude, E. Holmström, Rainer Krebs, Eeva Rouvinen, Antti I. Nykänen, Simo Syrjälä

Publikováno v: The Journal of Heart and Lung Transplantation. 39:S358-S359

Purpose Profound metabolic and molecular changes triggered by solid organ donor brain death may significantly affect posttransplant graft function. However, the effects of brain death on transplanted organs are poorly understood and no clinical bioma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68d8fbcc9e5f376d2f6613deed67c715
https://doi.org/10.1016/j.healun.2020.01.429

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Elevated Circulating Activin A Levels in Patients With Malignant Pleural Mesothelioma Are Related to Cancer Cachexia and Reduced Response to Platinum-based Chemotherapy

Autor: Eeva Rouvinen, Marjukka Myllärniemi, Katri Koli, Helena Lauri, Jari Räsänen, Eva Sutinen, Ilkka Ilonen, Karl B. Lemström, Juuso Paajanen, Olli Ritvos, Tommi Järvinen, Hely Ollila

Publikováno v: Clinical lung cancer. 21(3)

Activin A has previously been associated with cancer cachexia and in vitro resistance to platinum-based chemotherapy. We studied circulating activin A concentrations as well as activin B and their antagonists' follistatin/follistatin-like 3 in presur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7517fd9786fb664b0408b500106fd7
https://pubmed.ncbi.nlm.nih.gov/31734071

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Brain-Dead Donor-Derived Plasma Extracellular Vesicles May Induce Systemic Inflammation and Microvascular Dysfunction

Autor: A. Suoranta, Pirkko Mattila, Maija Puhka, S. Joo, Karl B. Lemström, Eeva Rouvinen, Kishor Dhaygude, Simo Syrjälä, Rainer Krebs

Publikováno v: The Journal of Heart and Lung Transplantation. 40:S125

Purpose Brain death (BD) may affect the function of grafts and the outcome of transplantation. However, the mechanisms of BD on grafts remain unclear. Considering extracellular vesicles (EVs) are promising mediators in cell-to-cell communication by d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15591d7c675d1bee3c09568129e4dce5
https://doi.org/10.1016/j.healun.2021.01.393

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Plasma Extracellular Vesicles May Regulate Inflammation and Hemodynamic Changes in Brain-Dead Donors

Autor: Simo Syrjälä, Peter Raivio, A. Suoranta, Maija Puhka, Pirkko Mattila, S. Joo, Matti Kankainen, Rainer Krebs, Eeva Rouvinen, Karl B. Lemström, Kishor Dhaygude

Publikováno v: The Journal of Heart and Lung Transplantation. 39:S180

Purpose Brain death causes hemodynamic instability and systemic inflammatory responses. However, the consequences of brain death on donor organs, and in particular on the microvascular endothelium, remains unknown. Extracellular vesicles (EV) are inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c3363f0bd245bbf60e9853798c24f36
https://doi.org/10.1016/j.healun.2020.01.758

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Transcriptome Profiles of the Circulating Extracellular Vesicles in Acute Lung Allograft Rejection

Autor: Karl B. Lemström, Kishor Dhaygude, Eeva Rouvinen, Pirkko Mattila, S. Joo, Matti Kankainen, Maija Puhka, Rainer Krebs

Publikováno v: The Journal of Heart and Lung Transplantation. 38:S146

Summary of Objectives The potential of Extracellular Vesicles (EVs) as novel diagnostic, prognostic and predictive biomarkers in transplantation has been noticed as they are known to contain various molecules related to cell-cell communication that v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85d986b304b3a71f9f65ff870e3abf93
https://doi.org/10.1016/j.healun.2019.01.348

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Donor Simvastatin Treatment Prevents Ischemia-Reperfusion and Acute Kidney Injury by Preserving Microvascular Barrier Function

Autor: Antti I. Nykänen, Karl B. Lemström, Ralica Arnaudova, Kirsi Rilla, Heikki Helin, Pipsa Saharinen, Rainer Krebs, Raija Tammi, M.A.I. Keranen, R. Tuuminen, Prson Gautam, Eeva Rouvinen

Publikováno v: American Journal of Transplantation. 13:2019-2034

Ischemia-reperfusion injury (IRI) after kidney transplantation may result in delayed graft function. We used rat renal artery clamping and transplantation models to investigate cholesterol-independent effects of clinically relevant single-dose perora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2f5cf67540ffe843e737995ec53e68
https://doi.org/10.1111/ajt.12315

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