Zobrazeno 1 - 2
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pro vyhledávání: '"Eesha Sheikh"'
Autor:
William P. Malachowski, James B. DuHadaway, Alexander J. Muller, Khoa N. Pham, Ariel Lewis-Ballester, George C. Prendergast, Jenny Wai, Eesha Sheikh, Syun Ru Yeh, Maria Winters, Shorouk O. Badir
Publikováno v:
European Journal of Medicinal Chemistry. 162:455-464
Tryptophan (Trp) catabolizing enzymes play an important and complex role in the development of cancer. Significant evidence implicates them in a range of inflammatory and immunosuppressive activities. Whereas inhibitors of indoleamine 2,3-dioxygenase
Autor:
William P. Malachowski, James B. DuHadaway, Alexander J. Muller, Jenny Wai, George C. Prendergast, Ariel Lewis-Ballester, Maria Winters, Syun Ru Yeh, Eesha Sheikh, Maisha Rahman, Shorouk O. Badir, Judith M. LaLonde
Publikováno v:
European journal of medicinal chemistry. 108
Indoleamine 2,3-dioxygenase-1 (IDO1) is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. Recently important advances have been made in understan