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pro vyhledávání: '"Eero Polvinen"'
Publikováno v:
Wednesday, April 26.
Autor:
Eero Polvinen, Eero Rissanen, Laura Airas, Marcus Sucksdorff, Jouni Tuisku, Markus Matilainen, Marjo Nylund, Anna Vuorimaa, Johanna Rokka
Publikováno v:
Brain
Sucksdorff et al. report that increased microglial and macrophage activation, as revealed by brain TSPO-PET, predicts multiple sclerosis progression independent of relapses during 4-year follow-up. Innate immune cell activation may thus contribute to
Publikováno v:
Brain Communications
Chronic active lesions are promotors of neurodegeneration and disease progression in multiple sclerosis. They harbour a dense rim of activated innate immune cells at the lesion edge, which promotes lesion growth and thereby induces damage. Convention