Zobrazeno 1 - 10
of 312
pro vyhledávání: '"Eero CASTRÉN"'
Autor:
Santtu Hellström, Antti Sajanti, Abhinav Srinath, Carolyn Bennett, Romuald Girard, Ying Cao, Janek Frantzén, Fredrika Koskimäki, Johannes Falter, Seán B. Lyne, Tomi Rantamäki, Riikka Takala, Jussi P. Posti, Susanna Roine, Jukka Puolitaival, Miro Jänkälä, Sulo Kolehmainen, Melissa Rahi, Jaakko Rinne, Eero Castrén, Janne Koskimäki
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 112 (2024)
Acute brain injuries (ABIs) pose a substantial global burden, demanding effective prognostic indicators for outcomes. This study explores the potential of urinary p75 neurotrophin receptor (p75NTR) concentration as a prognostic biomarker, particularl
Externí odkaz:
https://doaj.org/article/a83bd9a89d19490d8305c43d8fda22de
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Brain-derived neurotrophic factor (BDNF) signaling through its receptor TrkB has for a long time been recognized as a critical mediator of the antidepressant drug action, but BDNF signaling has been considered to be activated indirectly through the a
Externí odkaz:
https://doaj.org/article/64104453e6dd4360be2d161f431c1618
Autor:
Hanna Julku, Santeri Rouhinen, Henri J. Huttunen, Laura Lindberg, Johanna Liinamaa, Ville Saarela, Elina Karvonen, Sigrid Booms, Jyrki P. Mäkelä, Hannu Uusitalo, Eero Castrén, J. Matias Palva, Satu Palva
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Amblyopia is a developmental disorder associated with abnormal visual experience during early childhood commonly arising from strabismus and/or anisometropia and leading to dysfunctions in visual cortex and to various visual deficits. The di
Externí odkaz:
https://doaj.org/article/39e07a83bf9a4b2bac09d66a3de96769
Autor:
Senem Merve Fred, Suvi Kuivanen, Hasan Ugurlu, Plinio Cabrera Casarotto, Lev Levanov, Kalle Saksela, Olli Vapalahti, Eero Castrén
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Repurposing of currently available drugs is a valuable strategy to tackle the consequences of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on SARS-CoV-2 in cell culture models as well as in clinical practice.
Externí odkaz:
https://doaj.org/article/0cd2d56649b04388869f8e290921e48b
Autor:
Angelina Lesnikova, Plinio Casarotto, Rafael Moliner, Senem Merve Fred, Caroline Biojone, Eero Castrén
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Perineuronal nets (PNNs) have an important physiological role in the retention of learning by restricting cognitive flexibility. Their deposition peaks after developmental periods of intensive learning, usually in late childhood, and they help in lon
Externí odkaz:
https://doaj.org/article/03f5fb0774d44aa4a2294dc29547f850
Autor:
Madhusmita P. Sahu, Yago Pazos-Boubeta, Anna Steinzeig, Katja Kaurinkoski, Michela Palmisano, Olgierd Borowecki, Timo Petteri Piepponen, Eero Castrén
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Neurotrophin brain-derived neurotrophic factor (BDNF) and neurotransmitter serotonin (5-HT) regulate each other and have been implicated in several neuronal mechanisms, including neuroplasticity. We have investigated the effects of BDNF on serotonerg
Externí odkaz:
https://doaj.org/article/2e04428e57ba411096daf434288f7bde
Autor:
Liina Laukkanen, Cassiano R. A. F. Diniz, Sebastien Foulquier, Jos Prickaerts, Eero Castrén, Plinio C. Casarotto
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 773 (2021)
Blockers of angiotensin II type 1 receptor (AT1R) exert antidepressant-like effects by indirectly facilitating the activation of the angiotensin II type 2 receptor (AT2R), which leads to increased surface expression and transactivation of tropomyosin
Externí odkaz:
https://doaj.org/article/5e6b24cbe89043e590485d050b52c80c
Autor:
Hanna Antila, Maria Ryazantseva, Dina Popova, Pia Sipilä, Ramon Guirado, Samuel Kohtala, Ipek Yalcin, Jesse Lindholm, Liisa Vesa, Vinicius Sato, Joshua Cordeira, Henri Autio, Mikhail Kislin, Maribel Rios, Sâmia Joca, Plinio Casarotto, Leonard Khiroug, Sari Lauri, Tomi Taira, Eero Castrén, Tomi Rantamäki
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract A brief burst-suppressing isoflurane anesthesia has been shown to rapidly alleviate symptoms of depression in a subset of patients, but the neurobiological basis of these observations remains obscure. We show that a single isoflurane anesthe
Externí odkaz:
https://doaj.org/article/9b0a9c01a2904ac9a4a5d9e945138f61
Autor:
Eero Castrén, Masami Kojima
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 119-126 (2017)
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of depressed patients and at least the reduction in serum levels is reversible upon successful treatment. These data, together with a wealth of reports using differ
Externí odkaz:
https://doaj.org/article/13b03a41fdac43c0b6772f0d7be22ccb
Autor:
Cassiano R.A.F. Diniz, Caroline Biojone, Samia R.L. Joca, Tomi Rantamäki, Eero Castrén, Francisco S. Guimarães, Plinio C. Casarotto
Publikováno v:
PeerJ, Vol 7, p e6493 (2019)
Background Administration of anandamide (AEA) or 2-arachidonoylglycerol (2AG) induces CB1 coupling and activation of TRKB receptors, regulating the neuronal migration and maturation in the developing cortex. However, at higher concentrations AEA also
Externí odkaz:
https://doaj.org/article/a46180124cc14694adca4a59de7e86a9