Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Eelco J P de Koning"'
Autor:
Floris Groenendaal, Arie Franx, Rebecca C Painter, Ben Willem Mol, Bas B Van rijn, Leon de Wit, Doortje Rademaker, Daphne N Voormolen, Bettina M C Akerboom, Rosalie M Kiewiet-Kemper, Maarten R Soeters, Marion A L Verwij-Didden, Fahima Assouiki, Daniela H Schippers, Mechteld A R Vermeulen, Simone M I Kuppens, Mirjam M Oosterwerff, Joost J Zwart, Mattheus J M Diekman, Tatjana E Vogelvang, P Rob J Gallas, Sander Galjaard, Willy Visser, Nicole Horree, Tamira K Klooker, Rosemarie Laan, Rik Heijligenberg, Anjoke J M Huisjes, Thomas van Bemmel, Claudia A van Meir, Annewieke W van den Beld, Wietske Hermes, Solrun Vidarsdottir, Anneke G Veldhuis-Vlug, Remke C Dullemond, Henrique J Jansen, Marieke Sueters, Eelco J P de Koning, Judith O E H van Laar, Pleun Wouters-van Poppel, Marina E Sanson-van Praag, Eline S van den Akker, Catherine B Brouwer, Brenda B Hermsen, Bert Jan Potter van Loon, Olivier W H van der Heijden, Bastiaan E de Galan, Marsha van Leeuwen, Johanna A M Wijbenga, Karin de Boer, Arianne C van Bon, Flip W van der Made, Silvia A Eskes, Mirjam Zandstra, William H van Houtum, Babette A M Braams-Lisman, Catharina R G M Daemen-Gubbels, Maurice G A J Wouters, Richard G IJzerman, Nico A Mensing van Charante, Rolf Zwertbroek, Inge M Evers, Harold W de Valk, J Hans deVries
Publikováno v:
BMJ Open, Vol 9, Iss 8 (2019)
Introduction In women with gestational diabetes mellitus (GDM) requiring pharmacotherapy, insulin was the established first-line treatment. More recently, oral glucose lowering drugs (OGLDs) have gained popularity as a patient-friendly, less expensiv
Externí odkaz:
https://doaj.org/article/fcbb937143a248c0b10a815934bf79df
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219702 (2019)
AimsTo assess the planned diabetes care for the coming year and its associated factors in patients with Type 2 diabetes who have a person-centered annual consultation.MethodsImplementation study of a new consultation model in 47 general practices (pr
Externí odkaz:
https://doaj.org/article/11e17e7c9f614efab51a60e12e2af286
Autor:
Ekaterine Berishvili, Lorenzo Piemonti, Eelco J. P. de Koning, Sandra Lindstedt, Hanne Scholz, William E. Scott, Celine Auxenfans, Paul Johnson, Dominique E. Martin, Penilla Gunther, Devi Mey, Luciano Potena, Olivier Thaunat
Publikováno v:
Transplant International, Vol 37 (2024)
The field of organ transplantation is experiencing a transformative shift with the rise of Advanced Therapy Medicinal Products (ATMPs), which include gene therapies, somatic cell therapies, and tissue-engineered products. These therapies offer new, p
Externí odkaz:
https://doaj.org/article/3197a6c4257d4e74a3e8072cf5a2021f
Autor:
Roderick C Slieker, Matthias S Roost, Liesbeth van Iperen, H Eka D Suchiman, Elmar W Tobi, Françoise Carlotti, Eelco J P de Koning, P Eline Slagboom, Bastiaan T Heijmans, Susana M Chuva de Sousa Lopes
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005583 (2015)
Remodelling the methylome is a hallmark of mammalian development and cell differentiation. However, current knowledge of DNA methylation dynamics in human tissue specification and organ development largely stems from the extrapolation of studies in v
Externí odkaz:
https://doaj.org/article/6eff305b4df44ec0bed77e984e8fe9c6
Autor:
Frank Schwede, Daniela Bertinetti, Carianne N Langerijs, Michael A Hadders, Hans Wienk, Johanne H Ellenbroek, Eelco J P de Koning, Johannes L Bos, Friedrich W Herberg, Hans-Gottfried Genieser, Richard A J Janssen, Holger Rehmann
Publikováno v:
PLoS Biology, Vol 13, Iss 1, p e1002038 (2015)
The second messenger cAMP is known to augment glucose-induced insulin secretion. However, its downstream targets in pancreatic β-cells have not been unequivocally determined. Therefore, we designed cAMP analogues by a structure-guided approach that
Externí odkaz:
https://doaj.org/article/53ea691117ff4f0aada85ec8fd78efc2
Autor:
Robert Spinnler, Theresa Gorski, Katharina Stolz, Susanne Schuster, Antje Garten, Annette G Beck-Sickinger, Marten A Engelse, Eelco J P de Koning, Antje Körner, Wieland Kiess, Kathrin Maedler
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54106 (2013)
AIMS/HYPOTHESIS:Obesity is associated with a dysregulation of beta-cell and adipocyte function. The molecular interactions between adipose tissue and beta-cells are not yet fully elucidated. We investigated, whether or not the adipocytokine Nicotinam
Externí odkaz:
https://doaj.org/article/16ecf63bb88d40f49fadc4034a13247d
Autor:
Clare L Kirkpatrick, Piero Marchetti, Francesco Purrello, Salvatore Piro, Marco Bugliani, Domenico Bosco, Eelco J P de Koning, Marten A Engelse, Julie Kerr-Conte, François Pattou, Claes B Wollheim
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11053 (2010)
BackgroundGenome-wide association studies have identified susceptibility genes for development of type 2 diabetes. We aimed to examine whether a subset of these (comprising FTO, IDE, KCNJ11, PPARG and TCF7L2) were transcriptionally restricted to or e
Externí odkaz:
https://doaj.org/article/43c3c62a4a324538b6f4bf1ca4d663b2
Autor:
Cyril P. Landstra, Merel M. Ruissen, Hannah Regeer, Michiel F. Nijhoff, Bart E. P. B. Ballieux, Paul J. M. van der Boog, Aiko P. J. de Vries, Sasja D. Huisman, Eelco J. P. de Koning
Publikováno v:
Transplant International, Vol 37 (2024)
A public health emergency such as the COVID-19 pandemic has behavioral, mental and physical implications in patients with type 1 diabetes (T1D). To what extent the presence of a transplant further increases this burden is not known. Therefore, we com
Externí odkaz:
https://doaj.org/article/03c98fbd6a9d4f7b833023b3a9289eef
Autor:
Maarten C. Tol, Denise F. A. de Bont, Wouter P. C. Boon, Eelco J. P. de Koning, Aart A. van Apeldoorn
Publikováno v:
Transplant International, Vol 36 (2023)
Islet delivery devices (IDDs) offer potential benefits for islet transplantation and stem cell-based replacement in type 1 diabetes. Little is known about patient preferences regarding islet delivery device characteristics and implantation strategies
Externí odkaz:
https://doaj.org/article/6f5fd4ff3e1641839101000e06a83df9
Autor:
René van Tienhoven, Maria J. L. Kracht, Arno R. van der Slik, Sofia Thomaidou, Anouk H. G. Wolters, Ben N. G. Giepmans, Juan Pablo Romero Riojas, Michael S. Nelson, Françoise Carlotti, Eelco J. P. de Koning, Rob C. Hoeben, Arnaud Zaldumbide, Bart O. Roep
Publikováno v:
Diabetologia, 66(5), 884-896. SPRINGER
Aims/hypothesis Transcriptome analyses revealed insulin-gene-derived transcripts in non-beta endocrine islet cells. We studied alternative splicing of human INS mRNA in pancreatic islets. Methods Alternative splicing of insulin pre-mRNA was determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d078ebd9b4dbdb4aa6a72a2035c08148
http://hdl.handle.net/1887/3619412
http://hdl.handle.net/1887/3619412