Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Eelco D, Keuning"'
Autor:
Sanne G. S. Verberk, Hendrik J. P. van der Zande, Jeroen Baardman, Kyra E. de Goede, Karl J. Harber, Eelco D. Keuning, Joost M. Lambooij, Frank Otto, Anna Zawistowska-Deniziak, Helga E. de Vries, Menno P. J. de Winther, Bruno Guigas, Jan Van den Bossche
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Macrophages are highly plastic, key regulators of inflammation. Deregulation of macrophage activation can lead to excessive inflammation as seen in inflammatory disorders like atherosclerosis, obesity, multiple sclerosis and sepsis. Targeting intrace
Externí odkaz:
https://doaj.org/article/eedffe2b80ad4e5590a19202f028c287
Autor:
Reza Nadafi, Catarina Gago de Graça, Eelco D. Keuning, Jasper J. Koning, Sander de Kivit, Tanja Konijn, Sandrine Henri, Jannie Borst, Rogier M. Reijmers, Lisa G.M. van Baarsen, Reina E. Mebius
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4110-4123.e4 (2020)
Summary: Within lymph nodes (LNs), T follicular helper (TFH) cells help B cells to produce antibodies, which can either be protective or autoreactive. Here, we demonstrate that murine LN stromal cells (LNSCs) suppress the formation of autoreactive TF
Externí odkaz:
https://doaj.org/article/2b93e3f59882461b8aeb6a0f5572beb0
Autor:
Sandra J. van Vliet, Juan J. Garcia-Vallejo, Sjoerd T.T. Schetters, Martino Ambrosini, Eelco D. Keuning, Rieneke van de Ven, Sophie K. Horrevorts, Sanne Duinkerken, Tanja D. de Gruijl, Hakan Kalay, Laura J.W. Kruijssen, Dorian A. Stolk, Yvette van Kooyk
Publikováno v:
Molecular Therapy: Oncolytics, Vol 21, Iss, Pp 315-328 (2021)
Stolk, D A, Horrevorts, S K, Schetters, S T T, Kruijssen, L J W, Duinkerken, S, Keuning, E, Ambrosini, M, Kalay, H, van de Ven, R, Garcia-Vallejo, J J, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2021, ' Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition ', Molecular Therapy-Oncolytics, vol. 21, pp. 315-328 . https://doi.org/10.1016/j.omto.2021.04.009
Molecular Therapy-Oncolytics, 21, 315-328. Nature Publishing Group
Molecular Therapy Oncolytics
Stolk, D A, Horrevorts, S K, Schetters, S T T, Kruijssen, L J W, Duinkerken, S, Keuning, E, Ambrosini, M, Kalay, H, van de Ven, R, Garcia-Vallejo, J J, de Gruijl, T D, van Vliet, S J & van Kooyk, Y 2021, ' Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition ', Molecular Therapy-Oncolytics, vol. 21, pp. 315-328 . https://doi.org/10.1016/j.omto.2021.04.009
Molecular Therapy-Oncolytics, 21, 315-328. Nature Publishing Group
Molecular Therapy Oncolytics
Induction of tumor-specific cytotoxic CD8+ T cells (CTLs) via immunization relies on the presentation of tumor-associated peptides in major histocompatibility complex (MHC) class I molecules by dendritic cells (DCs). To achieve presentation of exogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5a3d38865d089274223fd3bdd4a98f
http://www.scopus.com/inward/record.url?scp=85107065086&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85107065086&partnerID=8YFLogxK
Autor:
Kyra E. de Goede, Karl J. Harber, Friederike S. Gorki, Sanne G.S. Verberk, Laszlo A. Groh, Eelco D. Keuning, Eduard A. Struys, Michel van Weeghel, Arvand Haschemi, Menno P.J. de Winther, Xanthe A.M.H. van Dierendonck, Jan Van den Bossche
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease, 1868
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1868(9):166427. Elsevier
de Goede, K E, Harber, K J, Gorki, F S, Verberk, S G S, Groh, L A, Keuning, E D, Struys, E A, van Weeghel, M, Haschemi, A, de Winther, M P J, van Dierendonck, X A M H & van den Bossche, J 2022, ' D-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation ', Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1868, no. 9, 166427 . https://doi.org/10.1016/j.bbadis.2022.166427
Biochimica et biophysica acta. Molecular basis of disease, 1868, 9
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1868(9):166427. Elsevier
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1868(9):166427. Elsevier
de Goede, K E, Harber, K J, Gorki, F S, Verberk, S G S, Groh, L A, Keuning, E D, Struys, E A, van Weeghel, M, Haschemi, A, de Winther, M P J, van Dierendonck, X A M H & van den Bossche, J 2022, ' D-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation ', Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1868, no. 9, 166427 . https://doi.org/10.1016/j.bbadis.2022.166427
Biochimica et biophysica acta. Molecular basis of disease, 1868, 9
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1868(9):166427. Elsevier
Contains fulltext : 251502.pdf (Publisher’s version ) (Open Access) Macrophages undergo extensive metabolic rewiring upon activation which assist the cell in roles beyond energy production and synthesis of anabolic building blocks. So-called immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77c480bd1717fb6bb688024b463114cb
http://hdl.handle.net/2066/251502
http://hdl.handle.net/2066/251502
Autor:
Antonio P Baptista, Ramon Roozendaal, Rogier M Reijmers, Jasper J Koning, Wendy W Unger, Mascha Greuter, Eelco D Keuning, Rosalie Molenaar, Gera Goverse, Marlous M S Sneeboer, Joke M M den Haan, Marianne Boes, Reina E Mebius
Publikováno v:
eLife, Vol 3 (2014)
Non-hematopoietic lymph node stromal cells shape immunity by inducing MHC-I-dependent deletion of self-reactive CD8+ T cells and MHC-II-dependent anergy of CD4+ T cells. In this study, we show that MHC-II expression on lymph node stromal cells is add
Externí odkaz:
https://doaj.org/article/99fa18f315d64e2dadbbd38e868cabf0
Autor:
Eelco D. Keuning, Manuel López-Cabrera, Evelina Ferrantelli, Marc Vila Cuenca, Georgios Liappas, Thomas L. Foster, Robert H.J. Beelen, Marc G. Vervloet
Publikováno v:
Kidney International, 89(3), 625-635. Nature Publishing Group
Ferrantelli, E, Liappas, G, Cuenca, M V, Keuning, E D, Foster, T L, Vervloet, M G, Lopez-Cabrera, M & Beelen, R H J 2016, ' The dipeptide alanyl-glutamine ameliorates peritoneal fibrosis and attenuates IL-17 dependent pathways during peritoneal dialysis ', Kidney International, vol. 89, no. 3, pp. 625-635 . https://doi.org/10.1016/j.kint.2015.12.005
Ferrantelli, E, Liappas, G, Cuenca, M V, Keuning, E D, Foster, T L, Vervloet, M G, Lopez-Cabrera, M & Beelen, R H J 2016, ' The dipeptide alanyl-glutamine ameliorates peritoneal fibrosis and attenuates IL-17 dependent pathways during peritoneal dialysis ', Kidney International, vol. 89, no. 3, pp. 625-635 . https://doi.org/10.1016/j.kint.2015.12.005
Peritoneal dialysis (PD) can result in chronic inflammation and progressive peritoneal membrane damage. Alanyl-Glutamine (Ala-Gln), a dipeptide with immunomodulatory effects, improved resistance of mesothelial cells to PD fluids. Recently, interleuki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac68f44ba1e9b41dc34eb02275f26fa5
https://doi.org/10.1016/j.kint.2015.12.005
https://doi.org/10.1016/j.kint.2015.12.005
Autor:
W. Talhout, Evelina Ferrantelli, Marc G. Vervloet, P. M. ter Wee, F. J. van Ittersum, M. Vila Cuenca, Robert H.J. Beelen, Nanne J. Paauw, Eelco D. Keuning
Publikováno v:
Vila Cuenca, M, Keuning, E D, Talhout, W, Paauw, N J, van Ittersum, F J, ter Wee, P M, Beelen, R H J, Vervloet, M G & Ferrantelli, E 2018, ' Differences in peritoneal response after exposure to low-GDP bicarbonate/lactate-buffered dialysis solution compared to conventional dialysis solution in a uremic mouse model ', INTERNATIONAL UROLOGY AND NEPHROLOGY, vol. 50, no. 6, pp. 1151-1161 . https://doi.org/10.1007/s11255-018-1872-3
International Urology and Nephrology
INTERNATIONAL UROLOGY AND NEPHROLOGY, 50(6), 1151-1161. Springer Netherlands
International Urology and Nephrology
INTERNATIONAL UROLOGY AND NEPHROLOGY, 50(6), 1151-1161. Springer Netherlands
Background: Long-term exposure of conventional peritoneal dialysis (PD) fluid is associated with structural membrane alterations and technique failure. Previously, it has been shown that infiltrating IL-17-secreting CD4+T cells and pro-fibrotic M2 ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b091970e92332874862497cf4e170041
https://research.vumc.nl/en/publications/84b2a920-0c71-482a-b2ec-0bed55f5480d
https://research.vumc.nl/en/publications/84b2a920-0c71-482a-b2ec-0bed55f5480d
Autor:
Jacob van den Born, Robert H.J. Beelen, Geert-Jan Tangelder, Piet M. ter Wee, Eelco D. Keuning, Anton A. van Lambalgen, Margot N. Schilte, Paolo Fabbrini, Mohammad Zareie
Publikováno v:
Microcirculation. 17:271-280
Peritoneal dialysis (PD)-induced peritonitis leads to dysfunction of the peritoneal membrane. During peritonitis, neutrophils are recruited to the inflammation site by rolling along the endothelium, adhesion, and transmigration through vessel walls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b10b126c47fc0f4561184965cb0ecc1
https://doi.org/10.1111/j.1549-8719.2010.00024.x
https://doi.org/10.1111/j.1549-8719.2010.00024.x
Autor:
Margot N. Schilte, Paolo Fabbrini, Robert H. J. Beelen, Jaap van den Born, Mammad Zareie, Eelco D. Keuning, Piet M. ter Wee
Publikováno v:
Nephrology, Dialysis, Transplantation, 24(12), 3669-3676. Oxford University Press
Fabbrini, P, Schilte, M N, Zareie, M, ter Wee, P M, Keuning, ED, Beelen, R H J & van den Born, J 2009, ' Celecoxib treatment reduces peritoneal fibrosis and angiogenesis and prevents ultrafiltration failure in experimental peritoneal dialysis ', Nephrology, Dialysis, Transplantation, vol. 24, no. 12, pp. 3669-3676 . https://doi.org/10.1093/ndt/gfp384
Nephrology Dialysis Transplantation, 24(12), 3669-3676. Oxford University Press
Fabbrini, P, Schilte, M N, Zareie, M, ter Wee, P M, Keuning, ED, Beelen, R H J & van den Born, J 2009, ' Celecoxib treatment reduces peritoneal fibrosis and angiogenesis and prevents ultrafiltration failure in experimental peritoneal dialysis ', Nephrology, Dialysis, Transplantation, vol. 24, no. 12, pp. 3669-3676 . https://doi.org/10.1093/ndt/gfp384
Nephrology Dialysis Transplantation, 24(12), 3669-3676. Oxford University Press
Background. Daily peritoneal exposure to peritoneal dialysis fluid (PDF) induces severe morphological alterations including fibrosis and angiogenesis that lead to a loss of peritoneal ultrafiltration (UF) capacity. Since cyclooxygenase (COX)-2 is inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa56f69e22589dc1c4df3abc95dcfd5
https://hdl.handle.net/11370/4b6da90d-7fd0-472a-a92b-8d1e37d29037
https://hdl.handle.net/11370/4b6da90d-7fd0-472a-a92b-8d1e37d29037
Autor:
Evelina Ferrantelli, M. Vila Cuenca, Guadalupe González-Mateo, Manuel López-Cabrera, Robert H.J. Beelen, Georgios Liappas, Eelco D. Keuning, Melissa Verkaik
Publikováno v:
BioMed Research International
BioMed Research International, 2015:106902. Hindawi Publishing Corporation
BioMed Research International, Vol 2015 (2015)
Ferrantelli, E, Liappas, G, Keuning, E D, Vila Cuenca, M, Gonzalez-Mateo, G, Verkaik, M, Lopez-Cabrera, M & Beelen, R H J 2015, ' A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid ', BioMed Research International, vol. 2015, 106902 . https://doi.org/10.1155/2015/106902
Digital.CSIC. Repositorio Institucional del CSIC
instname
BioMed Research International, 2015:106902. Hindawi Publishing Corporation
BioMed Research International, Vol 2015 (2015)
Ferrantelli, E, Liappas, G, Keuning, E D, Vila Cuenca, M, Gonzalez-Mateo, G, Verkaik, M, Lopez-Cabrera, M & Beelen, R H J 2015, ' A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid ', BioMed Research International, vol. 2015, 106902 . https://doi.org/10.1155/2015/106902
Digital.CSIC. Repositorio Institucional del CSIC
instname
Different animal models for peritoneal dialysis (PD) have been used in the past decades to develop PD fluids compatible with patient life and to identify markers of peritoneal fibrosis and inflammation. Only few of those studies have taken into accou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a692a5f82a65ac27abeda6c3ba2bd799
http://hdl.handle.net/10261/133192
http://hdl.handle.net/10261/133192