Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eef Hoeben"'
Autor:
Hélène Asnagli, Norbert Minet, Christina Pfeiffer, Eef Hoeben, Rebecca Lane, David Laughton, Louise Birch, Geraint Jones, Andrew Novak, Andrew E. Parker, Heinz Ludwig, Alain Fischer, Sylvain Latour, Philip A. Beer
Publikováno v:
HemaSphere, Vol 7, Iss 4, p e864 (2023)
Lymphoma is the most common hematological malignancy and is among the 10 most prevalent cancers worldwide. Although survival has been improved by modern immunochemotherapeutic regimens, there remains a significant need for novel targeted agents to tr
Externí odkaz:
https://doaj.org/article/94c683a95284402c9f04f59bf749bdad
Autor:
Philip Beer, Maureen Higgins, Hélène Asnagli, Eef Hoeben, Michael Hubank, Andrew Parker, Brian Schwartz
Publikováno v:
Blood. 140:12027-12028
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6415e0caca29842406b0257b9435ac27
https://doi.org/10.1182/blood-2022-159963
https://doi.org/10.1182/blood-2022-159963
Autor:
Pieter Annaert, Bing Qi, Christophe Buyck, Pieter Van Brantegem, Herman van Vlijmen, Jan Snoeys, Tom De Vocht, Eef Hoeben, Neel Deferm, An Vermeulen
Multidrug resistance-associated protein (MRP; ABCC gene family) mediated efflux transport plays an important role in the systemic and tissue exposure profiles of many drugs and their metabolites, and also of endogenous compounds like bile acids and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e276e92404d78cac4de6130df895535f
https://lirias.kuleuven.be/handle/20.500.12942/689486
https://lirias.kuleuven.be/handle/20.500.12942/689486
Autor:
Vera Rogiers, Agapios Sachinidis, Umesh Chaudhari, Pieter Annaert, René P. Zahedi, Albert Sickmann, Xiaoqi Jiang, Marlies Oorts, Hector C. Keun, Eva Gijbels, Laxmikanth Kollipara, Eef Hoeben, Annette Kopp-Schneider, Jan G. Hengstler, Mathieu Vinken, Joery De Kock, Tamara Vanhaecke, Robim Marcelino Rodrigues
Publikováno v:
Archives of Toxicology. 92:1939-1952
Bosentan is well known to induce cholestatic liver toxicity in humans. The present study was set up to characterize the hepatotoxic effects of this drug at the transcriptomic, proteomic, and metabolomic levels. For this purpose, human hepatoma-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0922659e4897f7f7ed55511e7e1d06
https://doi.org/10.1007/s00204-018-2214-z
https://doi.org/10.1007/s00204-018-2214-z
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1981
Over the last decade, liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the method of choice for the quantification of bile acids (BA) and their conjugates in different matrices, such as plasma, blood, urine, and cell lysates. Nume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dd4cb5888aafd17a9a6f603d7165d46
https://pubmed.ncbi.nlm.nih.gov/31016645
https://pubmed.ncbi.nlm.nih.gov/31016645
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994199
Over the last decade, liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the method of choice for the quantification of bile acids (BA) and their conjugates in different matrices, such as plasma, blood, urine, and cell lysates. Nume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f397b712f58a866e9351208ec74996ff
https://doi.org/10.1007/978-1-4939-9420-5_2
https://doi.org/10.1007/978-1-4939-9420-5_2
Autor:
Eef Hoeben, Adrian Dunne, An Vermeulen, Damayanthi Devineni, Willem de Winter, Martine Neyens
Publikováno v:
Clinical Pharmacokinetics. 55:209-223
Canagliflozin is an orally active, reversible, selective sodium-glucose co-transporter-2 inhibitor. A population pharmacokinetic (popPK) model of canagliflozin, including relevant covariates as sources of inter-individual variability, was developed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea69ef56871ee0159db37d888a9baeff
https://doi.org/10.1007/s40262-015-0307-x
https://doi.org/10.1007/s40262-015-0307-x
Autor:
Heidi De Smedt, Hiba Salih, Eef Hoeben, Peter de Boer, Ion Anghelescu, Luc Van Nueten, I. Kezic, Vikash K. Sinha
Publikováno v:
Journal of Psychopharmacology. 29:414-425
Metabotropic glutamate receptor-2 positive allosteric modulator, JNJ-40411813 (ADX71149), was characterised for clinical effects in healthy volunteers in two phase-1 studies. In study 1, healthy men received 50-, 100-, 150- or 225 mg and women receiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99dcc7158f678f9e32b7978ae069560b
https://doi.org/10.1177/0269881115573403
https://doi.org/10.1177/0269881115573403
Publikováno v:
Clinical Pharmacokinetics. 52:1005-1015
JNJ-37822681 is a selective, fast-dissociating dopamine D2-receptor antagonist currently in development as a candidate antipsychotic. The aim of the analyses was to develop a population pharmacokinetic model to describe the pharmacokinetics of JNJ-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a8c8495f978dc3a9c0cbc03af86069
https://doi.org/10.1007/s40262-013-0084-3
https://doi.org/10.1007/s40262-013-0084-3
Publikováno v:
Clinical pharmacokinetics. 52(11)
JNJ-37822681 is a selective, fast-dissociating dopamine D2-receptor antagonist currently in development as a candidate antipsychotic. The aim of the analyses was to develop a population pharmacokinetic model to describe the pharmacokinetics of JNJ-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6cf045e4ef52360b60a714eaa6cf9c8
https://pubmed.ncbi.nlm.nih.gov/23754735
https://pubmed.ncbi.nlm.nih.gov/23754735