Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ee W. Su"'
Publikováno v:
Glycobiology. 21:1258-1265
β-Galactoside-binding lectin 9 (galectin-9) is a tandem repeat-type member of the galectin family. It was initially characterized as an eosinophil chemoattractant and an inducer of apoptosis in thymocytes. Subsequently, galectin-9 was identified as
Autor:
Daniel J. Neitzke, Caitlin J. Moore, Christopher Bryce Johnson, Alicia Patterson, Samantha Suriano, Elizabeth Garrett-Mayer, Chrystal M. Paulos, Kristina Andrijauskaite, Ee W. Su, Shikhar Mehrotra, Zihai Li, David J. Cole, Ananda W. Goldrath, Mark P. Rubinstein, Andrew L. Doedens, Neizel Songalia
Publikováno v:
Science translational medicine. 7(311)
Interleukin-2 (IL-2) is a lymphocyte growth factor that is an important component of many immune-based cancer therapies. The efficacy of IL-2 is thought to be limited by the expansion of T regulatory cells, which express the high-affinity IL-2 recept
Autor:
Mitsuomi Hirashima, Lisa Bregoli, Nasim Kassam, David A. Hafler, Charles Lei, Rucha Chandwaskar, Jeffrey N. Bruce, Jozsef Karman, William Hastings, Lawrence P. Kane, Ee W Su, Vijay K. Kuchroo, Ana C. Anderson, David E. Anderson
Publikováno v:
Science. 318:1141-1143
CD4+T helper 1 (TH1) cells are important mediators of inflammation and are regulated by numerous pathways, including the negative immune receptor Tim-3. We found that Tim-3 is constitutively expressed on cells of the innate immune system in both mice
Publikováno v:
The FASEB Journal. 22
Publikováno v:
The Journal of Immunology. 182:90.13-90.13
Tim-3 is a type I transmembrane glycoprotein first identified through a screen for TH1-specific cell surface markers. Since then, it has been detected on a wide variety of cell types. Galectin-9, a β-galactoside binding lectin is the only known liga
Publikováno v:
The Journal of Immunology. 178:S131-S131
MUC1 (CD227) is a large (>400kDa), heavily glycosylated, type-I transmembrane protein present most notably on the apical surface of ductal epithelia. In epithelial adenocarcinomas MUC1 is overexpressed as a hypoglycosylated protein in a non-polarized
Autor:
Ana C. Anderson1, David E. Anderson1, Lisa Bregoli1, William D. Hastings1, Nasim Kassam1, Charles Lei1, Rucha Chandwaskar1, Jozsef Karman1, Ee W. Su2, Mitsuomi Hirashima3, Jeffrey N. Bruce4, Lawrence P. Kane2, Vijay K. Kuchroo1, David A. Hafler1
Publikováno v:
Science. 11/16/2007, Vol. 318 Issue 5853, p1141-1143. 3p.