Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Edyta, Szałek"'
Autor:
Konrad Lewandowski, Agnieszka Karbownik, Andrzej Czyrski, Hanna Urjasz, Joanna Stanisławiak-Rudowicz, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 81, Iss 2, Pp 263-278 (2024)
Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new anticancer drug. It is essential to find TDM-guided dosage for better safety and tolerability of patients. However, first, it is important to develop a suitable analyt
Externí odkaz:
https://doaj.org/article/d88f74306b6e406baae09e6342e10085
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionDepressive spectrum disorders are common and can hinder breastfeeding success. While medications typically pose minimal risk, the concerns persist. This is the first study that investigates the prevalence and characteristics of drug-relat
Externí odkaz:
https://doaj.org/article/d94d50cac166451cbcb7b1e35f7675ce
Autor:
Agnieszka Karbownik, Danuta Szkutnik-Fiedler, Filip Otto, Anna Wolc, Tomasz Grabowski, Zuzanna Maciejewska, Aleksandra Borycka, Edyta Szałek
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1387 (2024)
Background: In clinical practice, the prevalent problem of polypharmacy could result in increased risks of drug–drug interactions. Regorafenib (REG) is commonly co-administered with paracetamol (PA) as a treatment protocol in cancer patients with p
Externí odkaz:
https://doaj.org/article/d7e333eb1d0b4ac2a333231183d62e22
Autor:
Danuta Szkutnik-Fiedler, Filip Kwiatkowski, Monika Chomej, Dorota Kołodziej, Michał Michalak, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 2, Pp 277-287 (2023)
Most hospitalized patients with COVID-19 require complex pharmacotherapy due to underlying diseases, and polypharmacy may significantly increase the risk of drug-drug interactions (DDIs) and, in consequence, trigger adverse effects. The aim of this s
Externí odkaz:
https://doaj.org/article/2824e5cbbb024d909c0d9315f543c220
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 79:777-784
The prognosis for patients with acute myeloid leukaemia (AML) varies depending on genetic factors. The presence of mutations in the fms-like tyrosine kinase 3 (FLT3) gene is found in approximately 30% of AML patients. Midostaurin, a first-generation
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2111 (2021)
Bariatric surgery, which is an effective treatment for obesity, and gastrectomy, which is the primary treatment method for gastric cancer, alter the anatomy and physiology of the digestive system. Weight loss and changes in the gastrointestinal tract
Externí odkaz:
https://doaj.org/article/0dc9f459060846ae9b6aee24c029fa83
Autor:
Agnieszka Karbownik, Danuta Szkutnik-Fiedler, Tomasz Grabowski, Anna Wolc, Joanna Stanisławiak-Rudowicz, Radosław Jaźwiec, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 2172 (2021)
A combination of the tyrosine kinase inhibitor—sorafenib—and the opioid analgesic—morphine—can be found in the treatment of cancer patients. Since both are substrates of P-glycoprotein (P-gp), and sorafenib is also an inhibitor of P-gp, their
Externí odkaz:
https://doaj.org/article/eab7ca12e6b04047a2d2383652c3f609
Autor:
Edyta Szałek, Arkadiusz Spychala, Patrycja Kozanecka, Hanna Urjasz, Tomasz Grabowski, Anna Wolc, Elżbieta Długosz, Witold Kycler, Edmund Grześkowiak, Agnieszka Karbownik
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 79:401-407
Autor:
Dorota Kołodziej, Danuta Szkutnik-Fiedler, Hanna Urjasz, Tomasz Grabowski, Ryszard Bosacki, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 78:755-759
Autor:
Agnieszka Karbownik, Danuta Szkutnik-Fiedler, Andrzej Czyrski, Natalia Kostewicz, Paulina Kaczmarska, Małgorzata Bekier, Joanna Stanisławiak-Rudowicz, Marta Karaźniewicz-Łada, Anna Wolc, Franciszek Główka, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 600 (2020)
The tyrosine kinase inhibitor sorafenib is the first-line treatment for patients with hepatocellular carcinoma (HCC), in which hyperlipidemia and type 2 diabetes mellitus (T2DM) may often coexist. Protein transporters like organic cation (OCT) and mu
Externí odkaz:
https://doaj.org/article/d7cbe8cda674484da883f39507102113