Sensitivity and specificity of the high fluorescent lymphocyte count-gate on the Sysmex XE-5000 hematology analyzer for detection of peripheral plasma cells

Autor: Henriet Hendriks, Edwin van Mirre, Edwin ten Boekel, Gert Jan Vrielink, Nicole Tjon-a-Tsoi, Wim de Kieviet

Publikováno v: cclm. 49:685-688

Background: Plasma cells are one of the end products of the B-lymphocyte mediated immune response. These cells normally reside in the bone marrow or some peripheral lymphoid tissues. Increased numbers of plasma cells in the blood, usually indicates p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb3a366f00600083d608cce5612e4ae
https://doi.org/10.1515/cclm.2011.100

Copy Number Variation at the FCGR Locus Includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B

Autor: Willemijn B. Breunis, Masja de Haas, Martin de Boer, Gertjan Wolbink, Edwin van Mirre, Dirk Roos, Taco W. Kuijpers, Ellen van der Schoot, Nadja Laddach, Judy Geissler

Publikováno v: Human mutation, 30(5), E640-E650. Wiley-Liss Inc.

Human Fc gamma receptors (Fc gamma Rs) are glycoproteins that bind the Fc region of IgG. The genes encoding the low-affinity Fc gamma Rs are located on chromosome 1q23-24. Beside single nucleotide polymorphisms (SNPs), gene copy number variation (CNV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87e8f7664ef92916e2b46fd405bcd03
https://pure.amc.nl/en/publications/copy-number-variation-at-the-fcgr-locus-includes-fcgr3a-fcgr2c-and-fcgr3b-but-not-fcgr2a-and-fcgr2b(4873d0ef-99b6-4ddb-8629-85d73b7d9947).html

Neutrophil responsiveness to IgG, as determined by fixed ratios of mRNA levels for activating and inhibitory FcgammaRII (CD32), is stable over time and unaffected by cytokines

Autor: Taco W. Kuijpers, Willemijn B. Breunis, D Roos, Martin de Boer, Edwin van Mirre, C. Erik Hack, Judy Geissler

Publikováno v: Blood, 108(2), 584-590. American Society of Hematology

We tested the hypothesis that the ratio between the activating and inhibitory Fcgamma receptor type II (FcgammaRII) in neutrophils determines their responsiveness to immune complexes. We measured mRNA levels of FcgammaRII isoforms and observed differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd791e1953c0ce63819bd632576a771
https://pure.amc.nl/en/publications/neutrophil-responsiveness-to-igg-as-determined-by-fixed-ratios-of-mrna-levels-for-activating-and-inhibitory-fcgammarii-cd32-is-stable-over-time-and-unaffected-by-cytokines(1609f5c3-0726-4e43-9491-3592ac51d697).html

A novel splice variant of FcγRIIa

Autor: Joris van der Heijden, Abdulgabar Salama, Marcel van Deuren, Timo K. van den Berg, Edwin van Mirre, Judy Geissler, Dirk Roos, Taco W. Kuijpers, Jos W. M. van der Meer

Publikováno v: van der Heijden, J, Geissler, J, van Mirre, E, van Deuren, M, van der Meer, J W M, Salama, A, van den Berg, T K, Roos, D & Kuijpers, T W 2013, ' A novel splice variant of FcγRIIa : a risk factor for anaphylaxis in patients with hypogammaglobulinemia ', Journal of Allergy and Clinical Immunology, vol. 131, no. 5, pp. 1408-16.e5 . https://doi.org/10.1016/j.jaci.2013.02.009
Journal of Allergy and Clinical Immunology, 131, 1408-16 e5
Journal of Allergy and Clinical Immunology, 131, 5, pp. 1408-16 e5
Journal of Allergy and Clinical Immunology, 131(5), 1408-16.e5. Mosby Inc.
Journal of allergy and clinical immunology, 131(5), 1408-16.e5. Mosby Inc.

Contains fulltext : 116529.pdf (Publisher’s version ) (Closed access) BACKGROUND: Our index case was a patient with common variable immunodeficiency (CVID). She had anaphylactoid reactions on administration of intravenous immunoglobulin (IVIg) asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58b1fe1d73fdc35bbd6bdc0af28c5f9
https://doi.org/10.1016/j.jaci.2013.02.009