Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Edwin Zwart"'
Autor:
Hedwig M. Braakhuis, Eric R. Gremmer, Anne Bannuscher, Barbara Drasler, Sandeep Keshavan, Barbara Rothen-Rutishauser, Barbara Birk, Andreas Verlohner, Robert Landsiedel, Kirsty Meldrum, Shareen H. Doak, Martin J.D. Clift, Johanna Samulin Erdem, Oda A.H. Foss, Shanbeh Zienolddiny-Narui, Tommaso Serchi, Elisa Moschini, Pamina Weber, Sabina Burla, Pramod Kumar, Otmar Schmid, Edwin Zwart, Jolanda P. Vermeulen, Rob J. Vandebriel
Overall, the results of the 7 participating laboratories are quite similar. After exposing Calu-3 alone and Calu-3 co-cultures with macrophages, no effects of lipopolysaccharide (LPS), quartz (DQ12) or titanium dioxide (TiO2) NM-105 particles on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245bd559325ffda2512c00b83f58e046
http://hdl.handle.net/10029/626726
http://hdl.handle.net/10029/626726
Autor:
Annemieke de Vries, Harry van Steeg, Tyler Jacks, Jolanda van den Berg, Rudolf B. Beems, Gerard J. van den Aardweg, Conny Th.M. van Oostrom, Edwin Zwart, Wendy Bruins, Esther M. Hoogervorst
Supplementary Table S3 from Lack of p53 Ser389 Phosphorylation Predisposes Mice to Develop 2-Acetylaminofluorene–Induced Bladder Tumors but not Ionizing Radiation–Induced Lymphomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbb46afe2360e7b0a230e375fd80a98
https://doi.org/10.1158/0008-5472.22364153
https://doi.org/10.1158/0008-5472.22364153
Autor:
Annemieke de Vries, Jos Jonkers, Harry van Steeg, Tyler Jacks, Laura D. Attardi, Mirjam M. Schaap, Esther M. Hoogervorst, Rudolf B. Beems, Conny Th. M. vanOostrom, Edwin Zwart, Xiaoling Liu, Ewoud N. Speksnijder, Susan W.P. Wijnhoven
p53 alterations in human tumors often involve missense mutations that may confer dominant-negative or gain-of-function properties. Dominant-negative effects result in inactivation of wild-type p53 protein in heterozygous mutant cells and as such in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998571b6cea815dc8af80399fde46cc7
https://doi.org/10.1158/0008-5472.c.6495837
https://doi.org/10.1158/0008-5472.c.6495837
Autor:
Annemieke de Vries, Harry van Steeg, Tyler Jacks, Jolanda van den Berg, Rudolf B. Beems, Gerard J. van den Aardweg, Conny Th.M. van Oostrom, Edwin Zwart, Wendy Bruins, Esther M. Hoogervorst
Supplementary Figure S3 from Lack of p53 Ser389 Phosphorylation Predisposes Mice to Develop 2-Acetylaminofluorene–Induced Bladder Tumors but not Ionizing Radiation–Induced Lymphomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536fb8f2192726025ed136e07c8951db
https://doi.org/10.1158/0008-5472.22364168.v1
https://doi.org/10.1158/0008-5472.22364168.v1
Autor:
Annemieke de Vries, Harry van Steeg, Tyler Jacks, Jolanda van den Berg, Rudolf B. Beems, Gerard J. van den Aardweg, Conny Th.M. van Oostrom, Edwin Zwart, Wendy Bruins, Esther M. Hoogervorst
Supplementary Figure Legends from Lack of p53 Ser389 Phosphorylation Predisposes Mice to Develop 2-Acetylaminofluorene–Induced Bladder Tumors but not Ionizing Radiation–Induced Lymphomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fa9adb685b7feed4b012a39991c0e9
https://doi.org/10.1158/0008-5472.22364171.v1
https://doi.org/10.1158/0008-5472.22364171.v1
Autor:
Annemieke de Vries, Jos Jonkers, Harry van Steeg, Tyler Jacks, Laura D. Attardi, Mirjam M. Schaap, Esther M. Hoogervorst, Rudolf B. Beems, Conny Th. M. vanOostrom, Edwin Zwart, Xiaoling Liu, Ewoud N. Speksnijder, Susan W.P. Wijnhoven
Supplementary Table 1 from Dominant-Negative but not Gain-of-Function Effects of a p53.R270H Mutation in Mouse Epithelium Tissue after DNA Damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465a4863b550544aeb7c1f2669fa1b28
https://doi.org/10.1158/0008-5472.22368162
https://doi.org/10.1158/0008-5472.22368162
Autor:
Hedwig Braakhuis, Eric Gremmer, Anne Bannuscher, Barbara Drasler, Sandeep Keshavan, Barbara Rothen-Rutishauser, Barbara Birk, Andreas Verlohner, Robert Landsiedel, Kirsty Meldrum, Shareen Doak, Martin Clift, Johanna Samulin Erdem, Oda Foss, Shan Zienolddiny, Tommaso Serchi, Elisa Moschini, Pamina Weber, Sabina Burla, Pramod Kumar, Otmar Schmid, Edwin Zwart, Jolanda Vermeulen, Flemming Cassee, Rob Vandebriel
Publikováno v:
Annals of Work Exposures and Health. 67:i84-i85
The establishment of reliable and robust in vitro models for hazard assessment, moving away from animal testing, requires evaluation of model transferability and reproducibility. Lung models that can be exposed via the air, by means of an air-liquid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dbf3312a581603e12bb04893e438200
https://doi.org/10.1093/annweh/wxac087.205
https://doi.org/10.1093/annweh/wxac087.205
Autor:
Mirjam Luijten, Jeroen L. A. Pennings, Petra C. E. van Kesteren, Jos C. S. Kleinjans, Joost H.M. van Delft, W. H. Ralph Gottschalk, P. Edwin Zwart, Harry van Steeg
Publikováno v:
Toxicological Sciences, 123(1), 123-132. Oxford University Press
The current method to predict carcinogenicity of chemicals or drugs is the chronic 2-year rodent bioassay, which has disadvantages in duration, animal use, and specificity. An attractive alternative is the DNA repair-deficient Xpa(-/-)p53(+/-) mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681da9c59886a30ff96e1b720b2fca5b
https://pubmed.ncbi.nlm.nih.gov/21715664
https://pubmed.ncbi.nlm.nih.gov/21715664
Autor:
Åslund, Andreas K. O., Vandebriel, Rob J., Caputo, Fanny, de Jong, Wim H., Delmaar, Christiaan, Hyldbakk, Astrid, Rustique, Emilie, Schmid, Ruth, Snipstad, Sofie, Texier, Isabelle, Vernstad, Kai, Borgos, Sven Even F.
Publikováno v:
Drug Delivery & Translational Research; Sep2022, Vol. 12 Issue 9, p2114-2131, 18p
Autor:
Park, Margriet V. D. Z.1,2 (AUTHOR) margriet.park@rivm.nl, Verharen, Henny W.1 (AUTHOR), Zwart, Edwin1 (AUTHOR), Hernandez, Lya G.1 (AUTHOR), van Benthem, Jan1 (AUTHOR), Elsaesser, Andreas3 (AUTHOR), Barnes, Clifford3 (AUTHOR), McKerr, George3 (AUTHOR), Howard, C. Vyvyan3 (AUTHOR), Salvati, Anna4 (AUTHOR), Lynch, Iseult4 (AUTHOR), Dawson, Kenneth A.4 (AUTHOR), de Jong, Wim H.1 (AUTHOR)
Publikováno v:
Nanotoxicology. Jun2011, Vol. 5 Issue 2, p168-181. 14p.