Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Edwin Zambrano-Acosta"'
Autor:
Ann W. Silk, Steven J. O’Day, Howard L. Kaufman, Jennifer Bryan, Jacqueline T. Norrell, Casey Imbergamo, Daniella Portal, Edwin Zambrano-Acosta, Marisa Palmeri, Seymour Fein, Cai Wu, Leslie Guerreiro, Daniel Medina, Praveen K. Bommareddy, Andrew Zloza, Bernard A. Fox, Carmen Ballesteros-Merino, Yixin Ren, Darren Shafren, Mark Grose, Joshua A. Vieth, Janice M. Mehnert
Publikováno v:
Cancer immunology, immunotherapy : CII.
Background CAPRA (NCT02565992) evaluated Coxsackievirus A21 (V937) + pembrolizumab for metastatic/unresectable stage IIIB–IV melanoma. Methods Patients received intratumoral V937 on days 1, 3, 5, and 8 (then every 3 weeks [Q3W]) and intravenous pem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9d368838c23309ed35e63e7b2a991a
https://pubmed.ncbi.nlm.nih.gov/36445410
https://pubmed.ncbi.nlm.nih.gov/36445410
Autor:
Ann W. Silk, Bernard A. Fox, Jacqueline Norrell, Praveen K. Bommareddy, Jennifer L. Bryan, Daniella E Portal, Janice M. Mehnert, Seymour Fein, Joshua A. Vieth, Casey Imbergamo, Leslie Guerreiro, Cai Wu, Edwin Zambrano-Acosta, Steven J. O'Day, Andrew Zloza, Carmen Ballesteros-Merino, Marisa Palmeri, Howard L. Kaufman, Mark Grose, Daniel J. Medina, Darren R. Shafren
Publikováno v:
Cancer Research. 81:CT139-CT139
Background: Coxsackievirus A21 (V937) is an RNA oncolytic virus targeting ICAM-1 receptors. Pharmacodynamic effects of oncolytic viruses in the tumor microenvironment (TME), including increased CD8+ T cells and PD-L1 expression, support their use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::804ad9974cf0aaa5c7a829869f200fb6
https://doi.org/10.1158/1538-7445.am2021-ct139
https://doi.org/10.1158/1538-7445.am2021-ct139