Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Edwin W. Rubel"'
Autor:
Joseph A. Bellairs, Van A. Redila, Patricia Wu, Ling Tong, Alyssa Webster, Julian A. Simon, Edwin W. Rubel, David W. Raible
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
There are no approved therapeutics for the prevention of hearing loss and vestibular dysfunction from drugs like aminoglycoside antibiotics. While the mechanisms underlying aminoglycoside ototoxicity remain unresolved, there is considerable evidence
Externí odkaz:
https://doaj.org/article/730d1673827d458f99d9ea120893dffb
Autor:
Tamara M. Stawicki, Tor Linbo, Liana Hernandez, Lauren Parkinson, Danielle Bellefeuille, Edwin W. Rubel, David W. Raible
Publikováno v:
Biology Open, Vol 8, Iss 1 (2019)
Sensory hair cells are susceptible to numerous insults, including certain therapeutic medications like aminoglycoside antibiotics, and hearing and balance disorders are often a dose-limiting side effect of these medications. We show that mutations in
Externí odkaz:
https://doaj.org/article/80419cca077243c1b54d62b6835b8a75
Autor:
Tamara M. Stawicki, Liana Hernandez, Robert Esterberg, Tor Linbo, Kelly N. Owens, Arish N. Shah, Nihal Thapa, Brock Roberts, Cecilia B. Moens, Edwin W. Rubel, David W. Raible
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 7, Pp 2225-2235 (2016)
Hair cells possess a single primary cilium, called the kinocilium, early in development. While the kinocilium is lost in auditory hair cells of most species it is maintained in vestibular hair cells. It has generally been believed that the primary ro
Externí odkaz:
https://doaj.org/article/b1ded0c795714326a4abdfe48d02ce62
The zebrafish merovingian mutant reveals a role for pH regulation in hair cell toxicity and function
Autor:
Tamara M. Stawicki, Kelly N. Owens, Tor Linbo, Katherine E. Reinhart, Edwin W. Rubel, David W. Raible
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 847-856 (2014)
Control of the extracellular environment of inner ear hair cells by ionic transporters is crucial for hair cell function. In addition to inner ear hair cells, aquatic vertebrates have hair cells on the surface of their body in the lateral line system
Externí odkaz:
https://doaj.org/article/7e2a24f40b6b460795a785482b196dcf
Autor:
Joseph A, Bellairs, Van A, Redila, Patricia, Wu, Ling, Tong, Alyssa, Webster, Julian A, Simon, Edwin W, Rubel, David W, Raible
Publikováno v:
Frontiers in molecular neuroscience. 15
There are no approved therapeutics for the prevention of hearing loss and vestibular dysfunction from drugs like aminoglycoside antibiotics. While the mechanisms underlying aminoglycoside ototoxicity remain unresolved, there is considerable evidence
Publikováno v:
Neuromethods ISBN: 9781071620212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e40295117d180d1052cf29d9ec1b2013
https://doi.org/10.1007/978-1-0716-2022-9_1
https://doi.org/10.1007/978-1-0716-2022-9_1
Publikováno v:
Genomics
The Mongolian gerbil ( Meriones unguiculatus ) is a member of the rodent family that displays several features not found in mice or rats, including sensory specializations and social patterns more similar to those in humans. These features have made
Autor:
Patricia Wu, David W. Raible, Samantha N. Davis, Edwin W. Rubel, Julian A. Simon, Esra D. Camci
Publikováno v:
Hearing Research
Hearing and balance deficits have been reported during and following treatment with the antimalarial drug chloroquine. However, experimental work examining the direct actions of chloroquine on mechanoreceptive hair cells in common experimental models
Publikováno v:
Ingenierias. 23
espanolLa audicion requiere de la buena salud de las celulas ciliadas (vello) para garantizar que el sonido se detecte y procese correctamente. Estas se degeneran y mueren con la edad o por la exposicion a sonido intenso, entre otras causas, y normal
Autor:
Edwin W. Rubel
Publikováno v:
The Journal of the Acoustical Society of America. 150:A216-A216