Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Edwin R. Hughes"'
Autor:
Jane D. Funkhouser, Edwin R. Hughes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 619:506-514
Fetal rat lung removed at 15 days gestation and placed in organ culture incorporates choline into phosphatidylcholine. Addition of 10(-9) M dexamethasone resulted in increased rates of choline incorporation per micrograms protein after both 6 and 12
Publikováno v:
American Journal of Physiology-Legacy Content. 227:31-34
Autor:
Edwin R. Hughes, Jane D. Punkhouser
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 530:9-16
Fetal rat lung was placed in organ culture at 15 days gestation (22 days total gestation period), before biochemical and morphological development of the pulmonary surfactant system. At the fifth day of culture numerous Type II cells containing lamel
Autor:
Jane D. Funkhouser, Edwin R. Hughes
Publikováno v:
Archives of Biochemistry and Biophysics. 221:499-506
Lung lamellar bodies and liver mitochondria were used to demonstrate that soluble phospholipid transfer proteins from lung transfer phosphatidylcholine to both of these acceptors. The initial rate of transfer to lung lamellar bodies is about half tha
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 18:190-207
A method is presented consisting of modifications of Sweat's original fluorometric technic for the estimation of corticosterone and cortisol in plasma. These modifications include substitution of ethyl acetate for chloroform as the extracting solvent
Autor:
Edwin R. Hughes, George C. Cotzias
Publikováno v:
American Journal of Physiology-Legacy Content. 201:1061-1064
An effect of two glucocorticosteroids on the transport of the essential trace element, manganese, is described. Mice receiving high doses of prednisolone or cortisol accumulated more radiomanganese in their carcasses and retained less in their livers
Publikováno v:
American Journal of Physiology-Legacy Content. 202:392-394
Circulating concentrations of free 17-hydroxycorticosteroids (17-OHCS) and "cortisol" and "corticosterone" were determined in rats, guinea pigs, and rabbits. (Quotation marks indicate that fluorescence present in plasma of these species has identical
Publikováno v:
Experimental Biology and Medicine. 95:187-189
Publikováno v:
Biochemical and biophysical research communications. 70(2)
Fetal rat lungs placed in in vitro organ culture at 15.5 days gestation grow significantly based on accumulation of DNA and protein. In the experimental system described, DNA accumulated rapidly during the first three days in culture and increased fr
Autor:
Edwin R. Hughes, Jane D. Funkhouser
Publikováno v:
Journal of steroid biochemistry. 8(5)
Acceleration of fetal lung development by administration of glucocorticoid hormones has been demonstrated in a number of mammalian species. Dexamethasone 10 −5 M significantly depressed protein content per explant in the presence and absence of ins