Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Edwin N. Geissler"'
Publikováno v:
The Journal of Experimental Medicine
Interactions between products of the mouse W locus, which encodes the c-kit tyrosine kinase receptor, and the Sl locus, which encodes a ligand for c-kit receptor, which we have designated stem cell factor (SCF), have a critical role in the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186392edeb9d32b7f5b589e9cc27c3dd
http://europepmc.org/articles/PMC2119069
http://europepmc.org/articles/PMC2119069
Autor:
David E. Housman, M Liao, Stephen J. Galli, Edwin N. Geissler, Francis Hall Martin, J D Brook, Krisztina M. Zsebo
Publikováno v:
Somatic Cell and Molecular Genetics. 17:207-214
Recently a novel hematopoietic growth factor, stem cell factor (SCF), was cloned and demonstrated to be the ligand for the c-kit tyrosine kinase receptor. In the mouse, SCF is encoded by Sl (steel), a gene critical to the development of several disti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2c66280c2ab96425d9461ddc76bb36
https://doi.org/10.1007/bf01232978
https://doi.org/10.1007/bf01232978
Autor:
Krisztina M. Zsebo, Edwin N. Geissler, Stephen J. Galli, T Takeishi, Mindy Tsai, G. F. J. Newlands, H. R. P. Miller, K. E. Langley, Li-Sun Shih
Publikováno v:
The Journal of Experimental Medicine
Mast cell development is a complex process that results in the appearance of phenotypically distinct populations of mast cells in different anatomical sites. Mice homozygous for mutations at the W or S1 locus exhibit several phenotypic abnormalities,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19e9f18c40e4dd8f3c0573464a108cd
http://europepmc.org/articles/PMC2118877
http://europepmc.org/articles/PMC2118877
Autor:
Edwin N. Geissler, Krisztina M. Zsebo, Kenneth H. Okino, Neal C. Birkett, Frederick W. Jacobsen, Sidney Vaughn Suggs, David A. Williams, Stephen J. Galli, Kent A. Smith, Takashi Takeish, Harry L. Atkins, Francis Hall Martin, Bruce M. Cattanach, Keith Langley, Murdock Douglas C, Virginia C. Broudy, Rou Yin Hsu
Publikováno v:
Cell. 63:213-224
We have cloned a partial cDNA encoding murine stem cell factor (SCF) and show that the gene is syntenic with the SI locus on mouse chromosome 10. Using retroviral vectors to immortalize fetal liver stromal cell lines from mice harboring lethal mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b4428aa8e967d30514bd7dd741fcc7
https://doi.org/10.1016/0092-8674(90)90302-u
https://doi.org/10.1016/0092-8674(90)90302-u
Autor:
Martin E. Dorf, S D Wilson, B. A. Taylor, R. E. K. Fournier, D. E. Housman, P. D'Eustachio, P. P. Burd, P R Billings, P. A. Lalley, Edwin N. Geissler
Publikováno v:
The Journal of Experimental Medicine
The presence of positionally conserved amino acid residues suggests that the mouse proteins TCA3, P500, MIP1-alpha, MIP1-beta, and JE are members of a single gene family. These proteins are activation specific and can be expressed by both myeloid and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcc6f04856dcd2227fee196e6a08208
http://europepmc.org/articles/PMC2187827
http://europepmc.org/articles/PMC2187827
Publikováno v:
Biochemical and biophysical research communications. 191(3)
The c-kit protooncogene encodes a tyrosine kinase receptor expressed during ontogeny and adult life by several important and developmentally distinct cell lineages. Mice carrying germ line c-kit mutations exhibit deficiencies in most of these lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aba802ebcf494b3e57e2f0c6c0c231e
https://pubmed.ncbi.nlm.nih.gov/7682073
https://pubmed.ncbi.nlm.nih.gov/7682073
Publikováno v:
Advances in Immunology ISBN: 9780120224555
Publisher Summary This chapter focuses on the importance of stem cell factor (SCF) and the stem cell factor receptor (SCFR) in hematopoiesis and other complex developmental programs affecting melanocytes, germ cells, and mast cells that are predicted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33fa32bd4e6c0408937892a22790d87a
https://doi.org/10.1016/s0065-2776(08)60508-8
https://doi.org/10.1016/s0065-2776(08)60508-8
Publikováno v:
Annals of the New York Academy of Sciences. 664
Mast cells have been implicated in a wide variety of biological responses, but identifying the nature and importance of the mast cell's specific contributions to these reactions has been difficult. W/Wv mice have mutations affecting the c-kit tyrosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de73a23e92817a1f6c325dd0ea80f343
https://pubmed.ncbi.nlm.nih.gov/1280935
https://pubmed.ncbi.nlm.nih.gov/1280935
Autor:
Keith Langley, Mindy Tsai, Krisztina M. Zsebo, Stephen J. Galli, Edwin N. Geissler, Takashi Takeishi, Dean D. Metcalfe, Helen Thompson
We investigated the effects of a newly recognized multifunctional growth factor, the c-kit ligand stem cell factor (SCF), on mouse mast cell proliferation and phenotype. Recombinant rat SCF164 (rrSCF164) induced the development of large numbers of de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ae9b88c87700a8486905f905c40288
https://europepmc.org/articles/PMC52087/
https://europepmc.org/articles/PMC52087/
Publikováno v:
Blood. 79:2177-2178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::087106ba69dbf97159107fc187b92c0a
https://doi.org/10.1182/blood.v79.8.2177.2177
https://doi.org/10.1182/blood.v79.8.2177.2177