Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Edwin Mak"'
Autor:
Lisa Kuramoto, Jacquelyn Cragg, Ramachandiran Nandhagopal, Edwin Mak, Vesna Sossi, Raul de la Fuente-Fernández, A Jon Stoessl, Michael Schulzer
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76595 (2013)
To date, statistical methods that take into account fully the non-linear, longitudinal and multivariate aspects of clinical data have not been applied to the study of progression in Parkinson's disease (PD). In this paper, we demonstrate the usefulne
Externí odkaz:
https://doaj.org/article/85bc7ee360f24569ac9514626546ec58
Autor:
Rick Kornelsen, Matthew D. Walker, Vesna Sossi, Qing Miao, Mike Adam, Matthew J. Farrer, Christine Takhar, Nathan V. Lee, Edwin Mak, Katherine Dinelle, Michael Schulzer
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 35:1331-1338
Neuroinflammation in the aging rat brain was investigated using [11C]PBR28 microPET (positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p.G2019S transgenic rats; this mutation increases the risk of Parkinson's disease in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd57a16f26b8dda3def9bf0fbd461edf
https://doi.org/10.1038/jcbfm.2015.54
https://doi.org/10.1038/jcbfm.2015.54
Autor:
Pankaj Agarwal, A. Jon Stoessl, Ryan J. Uitti, Daryl Wile, Kazuko Hasegawa, Mark Guttman, Jing Zhang, Jan O. Aasly, Cyrus P. Zabetian, Zbigniew K. Wszolek, Nicole Neilson, Vesna Sossi, Elham Shahinfard, Nasim Vafai, Mike Adam, Matthew J. Farrer, Yu-Shin Ding, Katherine Dinelle, Jessamyn McKenzie, Audrey Strongosky, Michael Schulzer, Edwin Mak
Publikováno v:
The Lancet. Neurology. 16(5)
Summary Background People with Parkinson's disease can show premotor neurochemical changes in the dopaminergic and non-dopaminergic systems. Using PET, we assessed whether dopaminergic and serotonin transporter changes are similar in LRRK2 mutation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cb3047e85305a6701ba15aa481266b
https://pubmed.ncbi.nlm.nih.gov/28414642
https://pubmed.ncbi.nlm.nih.gov/28414642
Autor:
Donald B. Calne, A. Jon Stoessl, Lisa Kuramoto, Raúl de la Fuente-Fernández, Chong S. Lee, Siobhan McCormick, Jacquelyn J. Cragg, Wing Lok Au, Edwin Mak, Vesna Sossi, Jess McKenzie, Michael Schulzer, Thomas J. Ruth, Nandhagopal Ramachandiran
Publikováno v:
Annals of Neurology. 69:803-810
Objective: To investigate in vivo the impact of age on nigrostriatal dopamine dysfunction in Parkinson's disease (PD). Methods: PD patients (n = 78) and healthy control subjects (n = 35) underwent longitudinal positron emission tomography assessments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8761443e6e0792fd06737c13ec07b8
https://doi.org/10.1002/ana.22284
https://doi.org/10.1002/ana.22284
Publikováno v:
Parkinsonism & Related Disorders. 16:365-369
Since the initial results of the DATATOP study, considerable effort has been devoted over the past 20 years to test neuroprotective therapies for Parkinson's disease (PD). Two trials (CALM-PD-CIT and REAL-PET studies) used neuroimaging dopamine chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7d7dcb03b3de5b586797f2b03d8d2c
https://doi.org/10.1016/j.parkreldis.2010.04.008
https://doi.org/10.1016/j.parkreldis.2010.04.008
Autor:
Michael Schulzer, R. de la Fuente-Fernandez, Thomas J. Ruth, A. J. Stoessl, André R. Troiano, Edwin Mak, Vesna Sossi
Publikováno v:
Neurology. 72:1211-1216
Objective: Dyskinesias are common in Parkinson disease (PD). Prior investigations suggest that dopamine (DA) terminals compensate for abnormal DA transmission. We verified whether similar adaptations could be related to the development of treatment-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ab49086353a44e8054c3ea4ec81e8b
https://doi.org/10.1212/01.wnl.0000338631.73211.56
https://doi.org/10.1212/01.wnl.0000338631.73211.56
Autor:
Phuti S Ramaripa, Kwena D. Modibane, Katlego Makgopa, Ostar A Seerane, Manoko S Maubane-Nkadimeng, Edwin Makhado, Sadanand Pandey
Publikováno v:
Chemical Engineering Journal Advances, Vol 14, Iss , Pp 100485- (2023)
In clean energy, dye-sensitized solar cells (DSSCs) have become a key tool for the photovoltaic effect. Copper phthalocyanine nanowire (CuPcNW) dyes can be used in DSSCs to generate low-cost devices, light-harvesting, fast electron transfer materials
Externí odkaz:
https://doaj.org/article/ed0c31770e834ea49fec77a98480d1b8
Publikováno v:
Chest. 128:203-206
Context Despite the investigation of multiple therapeutic options, idiopathic pulmonary fibrosis (IPF) remains a devastating, progressively fatal disease. Much interest has focused on the use of interferon (IFN)-γ1b therapy, but the efficacy of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3d4408923bdf565f885ea88702dcf11
https://doi.org/10.1378/chest.128.1.203
https://doi.org/10.1378/chest.128.1.203
Publikováno v:
Parkinsonism & Related Disorders. 9:291-294
We have previously designed and validated a 10-item bilingual questionnaire, the Parkinson's Impact Scale (PIMS), as a disease-specific instrument to measure the impact of Parkinson's disease (PD) on the quality of life of patients with PD. In this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b761f6b57c0922b53c3c4f4c590d1fe4
https://doi.org/10.1016/s1353-8020(03)00019-1
https://doi.org/10.1016/s1353-8020(03)00019-1
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 27:137-142
Le tremblement de la tete dans la dystonie cerviale. Objectif: Comparer les caracteristiques cliniques, l'histoire naturelle et la reponse therapeutique de patients dystoniques avec tremblement de la tete (TT+) et sans tremblement de la tete (TT-). M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8050fef31df75a71202a1374e52c02e
https://doi.org/10.1017/s0317167100052240
https://doi.org/10.1017/s0317167100052240