Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Edwin Mak"'
Autor:
Lisa Kuramoto, Jacquelyn Cragg, Ramachandiran Nandhagopal, Edwin Mak, Vesna Sossi, Raul de la Fuente-Fernández, A Jon Stoessl, Michael Schulzer
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76595 (2013)
To date, statistical methods that take into account fully the non-linear, longitudinal and multivariate aspects of clinical data have not been applied to the study of progression in Parkinson's disease (PD). In this paper, we demonstrate the usefulne
Externí odkaz:
https://doaj.org/article/85bc7ee360f24569ac9514626546ec58
Autor:
Rick Kornelsen, Matthew D. Walker, Vesna Sossi, Qing Miao, Mike Adam, Matthew J. Farrer, Christine Takhar, Nathan V. Lee, Edwin Mak, Katherine Dinelle, Michael Schulzer
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 35:1331-1338
Neuroinflammation in the aging rat brain was investigated using [11C]PBR28 microPET (positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p.G2019S transgenic rats; this mutation increases the risk of Parkinson's disease in
Autor:
Phuti S Ramaripa, Kwena D. Modibane, Katlego Makgopa, Ostar A Seerane, Manoko S Maubane-Nkadimeng, Edwin Makhado, Sadanand Pandey
Publikováno v:
Chemical Engineering Journal Advances, Vol 14, Iss , Pp 100485- (2023)
In clean energy, dye-sensitized solar cells (DSSCs) have become a key tool for the photovoltaic effect. Copper phthalocyanine nanowire (CuPcNW) dyes can be used in DSSCs to generate low-cost devices, light-harvesting, fast electron transfer materials
Externí odkaz:
https://doaj.org/article/ed0c31770e834ea49fec77a98480d1b8
Autor:
Pankaj Agarwal, A. Jon Stoessl, Ryan J. Uitti, Daryl Wile, Kazuko Hasegawa, Mark Guttman, Jing Zhang, Jan O. Aasly, Cyrus P. Zabetian, Zbigniew K. Wszolek, Nicole Neilson, Vesna Sossi, Elham Shahinfard, Nasim Vafai, Mike Adam, Matthew J. Farrer, Yu-Shin Ding, Katherine Dinelle, Jessamyn McKenzie, Audrey Strongosky, Michael Schulzer, Edwin Mak
Publikováno v:
The Lancet. Neurology. 16(5)
Summary Background People with Parkinson's disease can show premotor neurochemical changes in the dopaminergic and non-dopaminergic systems. Using PET, we assessed whether dopaminergic and serotonin transporter changes are similar in LRRK2 mutation c
Autor:
Donald B. Calne, A. Jon Stoessl, Lisa Kuramoto, Raúl de la Fuente-Fernández, Chong S. Lee, Siobhan McCormick, Jacquelyn J. Cragg, Wing Lok Au, Edwin Mak, Vesna Sossi, Jess McKenzie, Michael Schulzer, Thomas J. Ruth, Nandhagopal Ramachandiran
Publikováno v:
Annals of Neurology. 69:803-810
Objective: To investigate in vivo the impact of age on nigrostriatal dopamine dysfunction in Parkinson's disease (PD). Methods: PD patients (n = 78) and healthy control subjects (n = 35) underwent longitudinal positron emission tomography assessments
Publikováno v:
Parkinsonism & Related Disorders. 16:365-369
Since the initial results of the DATATOP study, considerable effort has been devoted over the past 20 years to test neuroprotective therapies for Parkinson's disease (PD). Two trials (CALM-PD-CIT and REAL-PET studies) used neuroimaging dopamine chang
Autor:
Michael Schulzer, R. de la Fuente-Fernandez, Thomas J. Ruth, A. J. Stoessl, André R. Troiano, Edwin Mak, Vesna Sossi
Publikováno v:
Neurology. 72:1211-1216
Objective: Dyskinesias are common in Parkinson disease (PD). Prior investigations suggest that dopamine (DA) terminals compensate for abnormal DA transmission. We verified whether similar adaptations could be related to the development of treatment-r
Publikováno v:
Chest. 128:203-206
Context Despite the investigation of multiple therapeutic options, idiopathic pulmonary fibrosis (IPF) remains a devastating, progressively fatal disease. Much interest has focused on the use of interferon (IFN)-γ1b therapy, but the efficacy of this
Publikováno v:
Parkinsonism & Related Disorders. 9:291-294
We have previously designed and validated a 10-item bilingual questionnaire, the Parkinson's Impact Scale (PIMS), as a disease-specific instrument to measure the impact of Parkinson's disease (PD) on the quality of life of patients with PD. In this p
Autor:
Phuti S. Ramaripa, Kwena D. Modibane, Katlego Makgopa, Ostar A. Seerane, Manoko S. Maubane-Nkadimeng, Edwin Makhado, Mpitloane J. Hato, Morongwa E. Ramoroka, Kerileng M. Molapo, Deepanraj Balakrishnan, Emmanuel I. Iwuoha
Publikováno v:
Journal of Photochemistry and Photobiology, Vol 12, Iss , Pp 100142- (2022)
The titanium dioxide-metal-organic framework (TiO2−MOF) composite was prepared using the sol-gel method for photovoltaic applications. Raman analyses showed the presence of MOF clusters in the TiO2 sol-gel network. Using the Brunauer-Emmett-Teller
Externí odkaz:
https://doaj.org/article/51c12d985dcd48bda81003dd18d0a77b