Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Edwin J. Ostrin"'
Autor:
Ehsan Irajizad, Johannes F. Fahrmann, Iakovos Toumazis, Jody Vykoukal, Jennifer B. Dennison, Yu Shen, Kim-Anh Do, Edwin J. Ostrin, Ziding Feng, Samir Hanash
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105377- (2024)
Summary: Background: To determine whether an algorithm based on repeated measurements of a panel of four circulating protein biomarkers (4 MP) for lung cancer risk assessment results in improved performance over a single time measurement. Methods: We
Externí odkaz:
https://doaj.org/article/948079f1c64d4edc89872231ccdbf6c2
Autor:
Bo Yuan, Michael J. Clowers, Walter V. Velasco, Stephen Peng, Qian Peng, Yewen Shi, Marco Ramos-Castaneda, Melody Zarghooni, Shuanying Yang, Rachel L. Babcock, Seon Hee Chang, John V. Heymach, Jianjun Zhang, Edwin J. Ostrin, Stephanie S. Watowich, Humam Kadara, Seyed Javad Moghaddam
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
K-ras–mutant lung adenocarcinoma (KM-LUAD) is associated with abysmal prognosis and is tightly linked to tumor-promoting inflammation. A human mAb, canakinumab, targeting the proinflammatory cytokine IL-1β, significantly decreased the risk of lung
Externí odkaz:
https://doaj.org/article/4e8002b50ec543d8a5727b6a41432a09
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The observation that cancer acquires significant changes in its metabolism dates back nearly a century, to Otto Warburg noting that cancer cells preferentially utilize glycolysis even when there are no hypoxic conditions in the growth media. Altered
Externí odkaz:
https://doaj.org/article/f92c55cc308640a7af128e6c616bb8d6
Publikováno v:
Thoracic Surgery Clinics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b07fc73da4f7a1084a62c3b58d971c70
https://doi.org/10.1016/j.thorsurg.2023.04.004
https://doi.org/10.1016/j.thorsurg.2023.04.004
Autor:
Humam Kadara, Linghua Wang, Avrum Spira, Christopher S. Stevenson, Ignacio I. Wistuba, Junya Fujimoto, Steven M. Dubinett, Paul Scheet, John V. Heymach, Daniel Rosen, Edwin J. Ostrin, Seyed Javad Moghaddam, Jichao Chen, Don L. Gibbons, Lauren Averett Byers, Tina Cascone, Boris Sepesi, Jianjun Zhang, Junya Fukuoka, Luisa M. Solis, Maria Gabriela Raso, Edwin R. Parra, Dzifa Y. Duose, Carmen Behrens, Kostyantyn Krysan, Linh M. Tran, Samer Bazzi, Danielle R. Little, Kyle Chang, Beatriz Sanchez-Espiridion, Elena Bogatenkova, Jiexin Zhang, Hitoshi Dejima, Enyu Dai, Ruiping Wang, Dapeng Hao, Minghao Dang, Patrick M. Brennan, Kieko Hara, Warapen Treekitkarnmongkol, Guangchun Han, Ansam Sinjab
Supplementary Fig S9 and legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fe6f55635a81a7430936b768514b6a
https://doi.org/10.1158/2159-8290.22539742
https://doi.org/10.1158/2159-8290.22539742
Autor:
Humam Kadara, Linghua Wang, Avrum Spira, Christopher S. Stevenson, Ignacio I. Wistuba, Junya Fujimoto, Steven M. Dubinett, Paul Scheet, John V. Heymach, Daniel Rosen, Edwin J. Ostrin, Seyed Javad Moghaddam, Jichao Chen, Don L. Gibbons, Lauren Averett Byers, Tina Cascone, Boris Sepesi, Jianjun Zhang, Junya Fukuoka, Luisa M. Solis, Maria Gabriela Raso, Edwin R. Parra, Dzifa Y. Duose, Carmen Behrens, Kostyantyn Krysan, Linh M. Tran, Samer Bazzi, Danielle R. Little, Kyle Chang, Beatriz Sanchez-Espiridion, Elena Bogatenkova, Jiexin Zhang, Hitoshi Dejima, Enyu Dai, Ruiping Wang, Dapeng Hao, Minghao Dang, Patrick M. Brennan, Kieko Hara, Warapen Treekitkarnmongkol, Guangchun Han, Ansam Sinjab
Supplementary Figures S10-S20 and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228b4e59813c30776491a96c0beafb4e
https://doi.org/10.1158/2159-8290.22539757
https://doi.org/10.1158/2159-8290.22539757
Autor:
Seyed Javad Moghaddam, Edwin J. Ostrin, Jichao Chen, Humam Kadara, Roza Nurieva, Seon Hee Chang, Yi Yang, Andrei M. Alekseev, Samir Hanash, Scott E. Evans, Berenice A. Gutierrez, Belinda J. Hernandez, Soudabeh Daliri, Oscar Noble, Cynthia De la Garza Ramos, Nese Unver, Amber M. Cumpian, Mauricio S. Caetano, Nasim Khosravi
Somatic KRAS mutations are the most common oncogenic variants in lung cancer and are associated with poor prognosis. Using a Kras-induced lung cancer mouse model, CC-LR, we previously showed a role for inflammation in lung tumorigenesis through activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d447026e7868563a74da84a67babda78
https://doi.org/10.1158/2326-6066.c.6549209.v1
https://doi.org/10.1158/2326-6066.c.6549209.v1
Autor:
Humam Kadara, Linghua Wang, Avrum Spira, Christopher S. Stevenson, Ignacio I. Wistuba, Junya Fujimoto, Steven M. Dubinett, Paul Scheet, John V. Heymach, Daniel Rosen, Edwin J. Ostrin, Seyed Javad Moghaddam, Jichao Chen, Don L. Gibbons, Lauren Averett Byers, Tina Cascone, Boris Sepesi, Jianjun Zhang, Junya Fukuoka, Luisa M. Solis, Maria Gabriela Raso, Edwin R. Parra, Dzifa Y. Duose, Carmen Behrens, Kostyantyn Krysan, Linh M. Tran, Samer Bazzi, Danielle R. Little, Kyle Chang, Beatriz Sanchez-Espiridion, Elena Bogatenkova, Jiexin Zhang, Hitoshi Dejima, Enyu Dai, Ruiping Wang, Dapeng Hao, Minghao Dang, Patrick M. Brennan, Kieko Hara, Warapen Treekitkarnmongkol, Guangchun Han, Ansam Sinjab
Little is known of the geospatial architecture of individual cell populations in lung adenocarcinoma (LUAD) evolution. Here, we perform single-cell RNA sequencing of 186,916 cells from five early-stage LUADs and 14 multiregion normal lung tissues of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de452197db5a7eb7e4215d00daa1473
https://doi.org/10.1158/2159-8290.c.6549172.v1
https://doi.org/10.1158/2159-8290.c.6549172.v1
Autor:
Humam Kadara, Linghua Wang, Avrum Spira, Christopher S. Stevenson, Ignacio I. Wistuba, Junya Fujimoto, Steven M. Dubinett, Paul Scheet, John V. Heymach, Daniel Rosen, Edwin J. Ostrin, Seyed Javad Moghaddam, Jichao Chen, Don L. Gibbons, Lauren Averett Byers, Tina Cascone, Boris Sepesi, Jianjun Zhang, Junya Fukuoka, Luisa M. Solis, Maria Gabriela Raso, Edwin R. Parra, Dzifa Y. Duose, Carmen Behrens, Kostyantyn Krysan, Linh M. Tran, Samer Bazzi, Danielle R. Little, Kyle Chang, Beatriz Sanchez-Espiridion, Elena Bogatenkova, Jiexin Zhang, Hitoshi Dejima, Enyu Dai, Ruiping Wang, Dapeng Hao, Minghao Dang, Patrick M. Brennan, Kieko Hara, Warapen Treekitkarnmongkol, Guangchun Han, Ansam Sinjab
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a9b212ed9adc38e09b21a92e018561
https://doi.org/10.1158/2159-8290.22539739.v1
https://doi.org/10.1158/2159-8290.22539739.v1
Autor:
Samir M. Hanash, Ayumu Taguchi, Edwin J. Ostrin, Herbert Levine, D. Neil Watkins, Jennifer B. Dennison, Eunice N. Murage, Hong Wang, Hiroyuki Katayama, Mohit K. Jolly, Kieren D. Marini, Mitzi Aguilar, Muge Celiktas, Johannes F. Fahrmann, Satyendra C. Tripathi
Contains supplementary methods (Gene knockdown and overexpression, Sample preparation and mass spectrometric analysis, BrdU assay, Immunoblotting, Mathematical modeling for regulation of MCAM), supplementary references and supplementary figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2260fa94a8b7aef69b3762a4e636ee68
https://doi.org/10.1158/0008-5472.22414926.v1
https://doi.org/10.1158/0008-5472.22414926.v1