Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Edwin J Routledge"'
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287582 (2023)
BackgroundThe environmental prevalence of widely prescribed human pharmaceuticals that target key evolutionary conserved biomolecules present across phyla is concerning. Antidepressants, one of the most widely consumed pharmaceuticals globally, have
Externí odkaz:
https://doaj.org/article/04589db6d15745d18b923483afed2f58
Autor:
Satwant Kaur, Alice Baynes, Anne E Lockyer, Edwin J Routledge, Catherine S Jones, Leslie R Noble, Susan Jobling
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159852 (2016)
Gastropod mollusks have been proposed as alternative models for male reproductive toxicity testing, due to similarities in their reproductive anatomy compared to mammals, together with evidence that endocrine disrupting chemicals can cause effects in
Externí odkaz:
https://doaj.org/article/330551214a924ab2b1dcf64ca206e07a
Autor:
Satwant Kaur, Susan Jobling, Catherine S Jones, Leslie R Noble, Edwin J Routledge, Anne E Lockyer
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121259 (2015)
Nuclear receptors (NRs) are transcription regulators involved in an array of diverse physiological functions including key roles in endocrine and metabolic function. The aim of this study was to identify nuclear receptors in the fully sequenced genom
Externí odkaz:
https://doaj.org/article/5e4bf87b1a304c6d9b6399a43f162a86
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Disruptions to reproductive health in wildlife species inhabiting polluted environments is often found to occur alongside compromised immunity. However, research on impacts of aquatic pollution on freshwater mollusc immune responses is limited despit
Externí odkaz:
https://doaj.org/article/73319cb6645e469da1e451ff10e351ed
Publikováno v:
Environmental Toxicology and Chemistry. 41:880-887
Data Availability Statement: Data, associated metadata, and calculation tools are available from the corresponding author (mark.scrimshaw@brunel.ac.uk). Copyright © 2021 The Authors. Any uncertainty in determining numbers of microplastics in the env
Autor:
Ying, Wang, Alice, Baynes, Kofi O, Renner, Mingxing, Zhang, Mark D, Scrimshaw, Edwin J, Routledge
Publikováno v:
Toxics. 10(2)
The presence of plastic cosmetic microbeads in the environment due to their extensive use in society and inevitable dispersal into wastewater is concerning. Therefore, it is vital to understand the processes of microplastic uptake and elimination by
Publikováno v:
Frontiers in immunology. 13
Disruptions to reproductive health in wildlife species inhabiting polluted environments is often found to occur alongside compromised immunity. However, research on impacts of aquatic pollution on freshwater mollusc immune responses is limited despit
Autor:
Marion Abraham, Detlef Dietzmann, Gotthard Kunze, Joanna J Waniek, Margot Siebler, Helena Bielak, Kirstin Frost, Anne Schoop, Yvonne Müller, Martin Reif, Kirsten Simon, Ursula Wallentits, Etiënne L.M. Vermeirssen, Maike Harff, Anne Simon, Steffen Uhlig, Femke De Croock, Jörg E. Drewes, Eszter Simon, Tamara Zietek, Thomas B Bucher, Sabrina Schiwy, Freddy Dardenne, Edwin J. Routledge, Linda Gehrmann, Jochen Türk, Martin Giersberg, Martin Jähne, Michael Trimborn, Nicolas Beresford, K. Hellauer, Anett Werner, Karina Hettwer, Henner Hollert
Publikováno v:
The science of the total environment
Endocrine-active substances can adversely impact the aquatic ecosystems. A special emphasis is laid, among others, on the effects of estrogens and estrogen mimicking compounds. Effect-based screening methods like in vitro bioassays are suitable tools
An investigation into the biological effects of indirect potable reuse water using zebrafish embryos
Autor:
Francesco Falciani, S. Walker, Edwin J. Routledge, E. Lawton, E. Germain-Cripps, Philipp Antczak
Publikováno v:
Science of The Total Environment. 789:147981
© 2021 The Authors. Advanced treatment technologies are being assessed as a proactive measure to assist with the transformation of treated wastewater into a source of water for potable water production. We investigated the biological effects along a
Autor:
Alice Baynes, Susan Jobling, Carmel McDougall, Gemma Montagut Pino, Edwin J. Routledge, Anne E. Lockyer, Giang Huong Duong
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
In vertebrates, the steroidogenesis enzyme 5α-reductase converts testosterone to the more potent androgen 5α-dihydrotestosterone. Homologues of 5α-reductase genes have been identified in molluscs. However, recent findings suggest that vertebrate-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c93cd1edb2053a205ea70e37f8c29392
https://bura.brunel.ac.uk/handle/2438/19166
https://bura.brunel.ac.uk/handle/2438/19166