Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Edwin D. Savlov"'
Autor:
Edwin D. Savlov, Richard H. Creech, Arlene S. Ash, Geoffrey Falkson, Thomas J. Cunningham, Ernest C. Borden, DuPont Guerry, David A. Amato, Howard Bruckner
Publikováno v:
Investigational New Drugs. 5:293-297
In this Eastern Cooperative Oncology Group (ECOG) phase II study, dibromodulcitol (DBD) and a combination of actinomycin D, hydroxyurea, and cyclophosphamide (AHC) were compared with methyl-CCNU, the current ECOG standard, in patients who had receive
Publikováno v:
Cancer. 33:303-309
Biochemical analyses were carried out on tissues from 130 women with mammary carcinoma and 104 patients with benign breast lesions. The tissues were assayed for specific estrogen-binding proteins (EBP) and for several enzymes involved in carbohydrate
Publikováno v:
Cancer. 47:2214-2217
Primary breast cancers from 54 patients undergoing postsurgical adjuvant chemotherapy were analyzed for several enzymes and estrogen receptors to determine if biochemical parameters might offer a prognostic index for determining outcome of therapy. R
Publikováno v:
Cancer. 46:2797-2800
2 situations were studied to determine possible correlation between estrogen receptor (ER) content of breast cancer tumors and patients response to chemotherapy. The results presented were obtained from patients in 2 clinical settings: 1) advanced di
Autor:
Edwin D. Savlov, John M. Bennett, Robert F. Asbury, Craig S. McCune, E. Fölsch, Richard F. Bakemeier
Publikováno v:
Cancer. 47:1954-1958
Seventy-three women with metastatic breast cancer were treated with aminoglutethimide and dexamethasone. No complete responses occurred. Ten patients (16%) achieved partial responses (mean duration, 12 months). The proportions of patients responding
Publikováno v:
Cancer. 50:1734-1738
A logistic regression model, utilizing the activities of certain selected glycolytic enzymes and ER status measured on primary or recurrent lesions, has been applied to predict for response to combination chemotherapy regimens administered to women w
Publikováno v:
Cancer. 45:1993-2000
The value of estrogen receptor (ER) analysis in primary breast cancer samples as a potential prognostic factor was examined in three clinical situations: time to recurrence in patients with no therapy after mastectomy, failure of patients receiving a
Publikováno v:
Cancer. 28:1161-1164
Autor:
Edwin D. Savlov, Raman Qazi
Publikováno v:
Cancer. 49:600-602
Forty patients with malignant ascites refractory to conventional medical management had peritoneovenous shunt for palliation. The shunt provided effective palliation in 28 with decrease in weight, abdominal girth, number of paracenteses required and
Publikováno v:
Cancer. 39:539-541
Tumor tissues from approximately 500 primary and metastatic human breast cancers were analyzed by the dextran-coated charcoal method and the sucrose gradient analysis in order to determine the level of estrogen receptors. Patients were treated in acc