Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Edwin C. Cheung"'
Autor:
Jonathan R. Brody, Dan A. Dixon, Jordan M. Winter, Paul M. Campbell, Charles J. Yeo, Avinoam Nevler, Cinthya Y. Lowder, Austin Goetz, Eric Londin, Matthew C. Stout, Carmella Romeo, Nicole C. Mambelli-Lisboa, Saswati N. Chand, Ranjan Preet, Mahsa Zarei, Edwin C. Cheung, Shruti Lal
Figure S1: HuR inhibition was successfully achieved by CRISPR/cas9 system. Figure S2: HuR inhibition sensitizes cells to drugs. Figure S3: PDA xenografts with HuR inhibition failed to form tumors. Table S1: Lists the three guide RNAs used to generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de7643e4ff5af091d58ad9d40030fb3
https://doi.org/10.1158/1541-7786.22512819.v1
https://doi.org/10.1158/1541-7786.22512819.v1
Autor:
Jonathan R. Brody, Dan A. Dixon, Jordan M. Winter, Paul M. Campbell, Charles J. Yeo, Avinoam Nevler, Cinthya Y. Lowder, Austin Goetz, Eric Londin, Matthew C. Stout, Carmella Romeo, Nicole C. Mambelli-Lisboa, Saswati N. Chand, Ranjan Preet, Mahsa Zarei, Edwin C. Cheung, Shruti Lal
Pancreatic ductal adenocarcinoma (PDA) is the third leading cause of cancer-related deaths in the United States, whereas colorectal cancer is the third most common cancer. The RNA-binding protein HuR (ELAVL1) supports a pro-oncogenic network in gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893d87f75b99f780caa6bbbab5107d71
https://doi.org/10.1158/1541-7786.c.6540345
https://doi.org/10.1158/1541-7786.c.6540345
Autor:
Ye-Ran Yang, Chih-Chieh Yu, Dillon C. Karg, Emily Chen, Han Yan, Ji Luo, Ayman Lee Youssof, Yi Miao, Gloria H. Su, Haoqiang Ying, Jun Yan, Wanglong Qiu, Edwin C Cheung, Richard A. Friedman, Stuart A. Fine
Publikováno v:
Oncogene. 40:6759-6771
Human pancreatic ductal adenocarcinoma (PDAC) harboring one KRAS mutant allele often displays increasing genomic loss of the remaining wild-type (WT) allele (known as LOH at KRAS) as tumors progress to metastasis, yet the molecular ramification of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c873e9388dc0826ed2acf9d284ee9a73
https://doi.org/10.1038/s41388-021-02040-9
https://doi.org/10.1038/s41388-021-02040-9
Autor:
Helen Remotti, Elizabeth Wang, Joo Hee Lee, Wanglong Qiu, Sophia M. Tang, Gloria H. Su, Edwin C. Cheung, Ayman Lee Youssof, Lily Dobberteen
Publikováno v:
Cancer Letters. 423:71-79
PanINs and IPMNs are the two most common precursor lesions that can progress to invasive pancreatic ductal adenocarcinoma (PDA). DCLK1 has been identified as a biomarker of progenitor cells in PDA progressed from PanINs. To explore the potential role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee3f6350bfa7d253afb087aae9174d6
https://doi.org/10.1016/j.canlet.2018.03.009
https://doi.org/10.1016/j.canlet.2018.03.009
Autor:
Matthew C. Stout, Jordan M. Winter, Avinoam Nevler, Ranjan Preet, Eric Londin, Charles J. Yeo, Cinthya Y. Lowder, Shruti Lal, Edwin C. Cheung, Dan A. Dixon, Saswati N. Chand, Austin Goetz, Paul M. Campbell, Carmella Romeo, Jonathan R. Brody, Nicole C. Mambelli-Lisboa, Mahsa Zarei
Publikováno v:
Molecular Cancer Research. 15:696-707
Pancreatic ductal adenocarcinoma (PDA) is the third leading cause of cancer-related deaths in the United States, whereas colorectal cancer is the third most common cancer. The RNA-binding protein HuR (ELAVL1) supports a pro-oncogenic network in gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa7919454ade0955bd5f5ccabe582ad
https://doi.org/10.1158/1541-7786.mcr-16-0361
https://doi.org/10.1158/1541-7786.mcr-16-0361
Autor:
Han Yan, Chih-Chieh Yu, Dillon C. Karg, Dario Garcia-Carracedo, Ji Luo, Edwin C Cheung, Stuart A. Fine, Emily Chen, Richard A. Friedman, Yi Miao, Ye-Ran Yang, Wanglong Qiu, Ayman Lee, Gloria H. Su, Juan Yan
Publikováno v:
Cancer Research. 79:I17-I17
KRAS is a major oncogenic driver in pancreatic ductal adenocarcinoma (PDAC). Intriguingly, human tumors with RAS mutations often display loss of the remaining wild-type (WT) allele, including PDAC. We previously reported that selective loss of WT Kra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969590130edd152e46be47d0eae1c4e0
https://doi.org/10.1158/1538-7445.panca19-i17
https://doi.org/10.1158/1538-7445.panca19-i17
Autor:
Wanglong, Qiu, Helen E, Remotti, Sophia M, Tang, Elizabeth, Wang, Lily, Dobberteen, Ayman, Lee Youssof, Joo Hee, Lee, Edwin C, Cheung, Gloria H, Su
Publikováno v:
Cancer letters. 423
PanINs and IPMNs are the two most common precursor lesions that can progress to invasive pancreatic ductal adenocarcinoma (PDA). DCLK1 has been identified as a biomarker of progenitor cells in PDA progressed from PanINs. To explore the potential role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf6ca4a67359d525ea82583733ca501c
https://pubmed.ncbi.nlm.nih.gov/29526803
https://pubmed.ncbi.nlm.nih.gov/29526803
Publikováno v:
Journal of Vascular Surgery. 67:e148-e149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f17635bf0d4508d08edcaad8f964400f
https://doi.org/10.1016/j.jvs.2018.03.204
https://doi.org/10.1016/j.jvs.2018.03.204
Autor:
Chih-Chieh Yu, Han Yan, Edwin C. Cheung, Dillon C. Carg, Stuart A. Fine, Dario Garcia-Carracedo, Yi Miao, Ji Luo, Wei-Yann Tsai, Ayman Lee Youssorf, Gloria H. Su, Wanglong Qiu
Publikováno v:
Annals of Pancreatic Cancer. 1:AB002-AB002
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b13e3c8ca25d567b58502d0295cff67
https://doi.org/10.21037/apc.2018.ab002
https://doi.org/10.21037/apc.2018.ab002
Abstract 2854: CRISPR knockout of HuR in pancreatic cancer cells causes a xenograft lethal phenotype
Autor:
Eric Londin, Jordan M. Winter, Edwin C. Cheung, Carmella Romeo, Joseph A. Cozzitorto, Nicole C. Mambelli-Lisboa, Shruti Lal, Charles J. Yeo, Mahsa Zarei, Saswati N. Chand, Jonathan R. Brody, Kevin O'Hayer
Publikováno v:
Cancer Research. 76:2854-2854
Pancreatic ductal adenocarcinoma (PDA) is the most prevalent type of pancreatic cancer and will soon become the second leading cause of cancer related deaths in the U.S. Studies show that the nuclear localized mRNA-binding protein HuR (ELAVL1) is act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e40717e4c7d02e350b349ef6e678d182
https://doi.org/10.1158/1538-7445.am2016-2854
https://doi.org/10.1158/1538-7445.am2016-2854