Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Edwin C K, Wan"'
Autor:
Kelly L. Monaghan, Wen Zheng, Halima Akhter, Lei Wang, Amanda G. Ammer, Peng Li, Jian-Xin Lin, Gangqing Hu, Warren J. Leonard, Edwin C. K. Wan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In response to external stimuli during immune responses, monocytes can have multifaceted roles such as pathogen clearance and tissue repair. However, aberrant control of monocyte activation can result in chronic inflammation and subsequent tissue dam
Externí odkaz:
https://doaj.org/article/12045bbafd524595805dc67907514100
Autor:
Breanne Y. Farris, Kelly L. Monaghan, Wen Zheng, Courtney D. Amend, Heng Hu, Amanda G. Ammer, James E. Coad, Xuefang Ren, Edwin C. K. Wan
Publikováno v:
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Abstract Introduction Stroke‐associated pneumonia (SAP) is a major cause of mortality in patients who have suffered from severe ischemic stroke. Although multifactorial in nature, stroke‐induced immunosuppression plays a key role in the developme
Externí odkaz:
https://doaj.org/article/cf5c7f3a264d403288c9846512a01c0c
Autor:
Jialong Yang, Hong-Xia Wang, Jinhai Xie, Lei Li, Jinli Wang, Edwin C. K. Wan, Xiao-Ping Zhong
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
CD4+ T helper (TH) cells are critical for protective adaptive immunity against pathogens, and they also contribute to the pathogenesis of autoimmune diseases. How TH differentiation is regulated by the TCR's downstream signaling is still poorly under
Externí odkaz:
https://doaj.org/article/2cea0333927641d2a975666d1f71af73
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Multiple sclerosis (MS) is a chronic inflammatory disease mediated by a complex interaction between the autoreactive lymphocytes and the effector myeloid cells within the central nervous system (CNS). In a murine model of MS, experimental autoimmune
Externí odkaz:
https://doaj.org/article/ac28536f28374b359d48b45c3fc7f184
Autor:
Edwin C. K. Wan
Publikováno v:
Cells, Vol 9, Iss 10, p 2223 (2020)
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults [...]
Externí odkaz:
https://doaj.org/article/e2e25c5db7ca427591717c1dec6f69ec
Autor:
Courtney D. Amend, Edwin C. K. Wan, Heng Hu, James E. Coad, Xuefang Ren, Breanne Y. Farris, Wen Zheng, Kelly L. Monaghan, Amanda Gatesman Ammer
Publikováno v:
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Immunity, Inflammation and Disease, Vol 7, Iss 4, Pp 326-341 (2019)
Introduction Stroke‐associated pneumonia (SAP) is a major cause of mortality in patients who have suffered from severe ischemic stroke. Although multifactorial in nature, stroke‐induced immunosuppression plays a key role in the development of SAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc5a25f220e6cf9dfa488025d82085f
https://doi.org/10.1002/iid3.277
https://doi.org/10.1002/iid3.277
Autor:
Kelly L. Monaghan, Drake Aesoph, Amanda G. Ammer, Wen Zheng, Shokofeh Rahimpour, Breanne Y. Farris, Camille A. Spinner, Peng Li, Jian-Xin Lin, Zu-Xi Yu, Vanja Lazarevic, Gangqing Hu, Warren J. Leonard, Edwin C. K. Wan
Publikováno v:
Proc Natl Acad Sci U S A
Signal transducers and activators of transcription 5 A and B (STAT5A & B) play a critical role in mediating cellular responses following cytokine stimulation. STAT5 proteins critically signal via the formation of dimers through SH2 domain interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c6cd0094b9b72be30277da5c54eac2
https://doi.org/10.4049/jimmunol.208.supp.44.05
https://doi.org/10.4049/jimmunol.208.supp.44.05
Publikováno v:
J Vis Exp
Immune cell expansion, activation, and trafficking to the lungs, which are controlled by the expression of multiple cytokines and chemokines, may be altered by severe brain injury. This is evidenced by the fact that pneumonia is a major cause of mort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d88fd26e978f961338f3f28dfc4a81
https://doi.org/10.3791/61359
https://doi.org/10.3791/61359
Autor:
Kelly L. Monaghan, Edwin C. K. Wan
Publikováno v:
Cells
Cells, Vol 9, Iss 3, p 611 (2020)
Cells, Vol 9, Iss 3, p 611 (2020)
Multiple sclerosis (MS) is an immune-mediated disease that predominantly impacts the central nervous system (CNS). Animal models have been used to elucidate the underpinnings of MS pathology. One of the most well-studied models of MS is experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de0c3349fc88c1474e44edb827de5c1
http://europepmc.org/articles/PMC7140439
http://europepmc.org/articles/PMC7140439
Autor:
Lei Li, Yongping Chen, Huishan Tao, Xiao-Ping Zhong, Edwin C K Wan, Yun Pan, Zhiming Hu, Jimin Gao, Shimeng Zhang, Li Ma, Wenhai Deng, Jinhai Xie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3135fa48571440691d9a1e76dc714ba7
https://doi.org/10.1002/eji.201948289/v2/response1
https://doi.org/10.1002/eji.201948289/v2/response1
