Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Edwin A. Apilado"'
Autor:
Lily M. Blair, Joseph M. Juan, Lafia Sebastian, Vy B. Tran, Wensheng Nie, Gregory D. Wall, Mehmet Gerceker, Ian K. Lai, Edwin A. Apilado, Gabriel Grenot, David Amar, Giorgia Foggetti, Mariana Do Carmo, Zeynep Ugur, Debbie Deng, Alex Chenchik, Maria Paz Zafra, Lukas E. Dow, Katerina Politi, Jonathan J. MacQuitty, Dmitri A. Petrov, Monte M. Winslow, Michael J. Rosen, Ian P. Winters
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Tumors acquire alterations in oncogenes and tumor suppressor genes in an adaptive walk through the fitness landscape of tumorigenesis. However, the interactions between oncogenes and tumor suppressor genes that shape this landscape remain po
Externí odkaz:
https://doaj.org/article/d8b8fe0a0e6941c7a811944dff8fc5cc
Autor:
Paul J. McMurdie, Ian P. Winters, Lily M. Blair, Lafia Sebastian, Vy Tran, Gabriel Grenot, Edwin A. Apilado, Ian K. Lai, Gregory D. Wall, Dmitri A. Petrov, Monte M. Winslow, Michael J. Rosen, Joseph Juan
Publikováno v:
Cancer Research. 83:2789-2789
Cancer is characterized by diverse genomic alterations that change cell state and can modify therapy responses. In some cases, the relationships between genotype and drug responses are obvious, such as the response of tumors with defined oncogenic mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa40adf2377579e78ebee94007dfb388
https://doi.org/10.1158/1538-7445.am2023-2789
https://doi.org/10.1158/1538-7445.am2023-2789
Autor:
Lily M. Blair, Joseph M. Juan, Lafia Sebastian, Vy B. Tran, Wensheng Nie, Gregory D. Wall, Mehmet Gerceker, Ian K. Lai, Edwin A. Apilado, Gabriel Grenot, David Amar, Giorgia Foggetti, Mariana Do Carmo, Zeynep Ugur, Debbie Deng, Alex Chenchik, Maria Paz Zafra, Lukas E. Dow, Katerina Politi, Jonathan J. MacQuitty, Dmitri A. Petrov, Monte M. Winslow, Michael J. Rosen, Ian P. Winters
Publikováno v:
Cancer Research. 83:1172-1172
Cancer progression is a quintessential example of a walk on an adaptive fitness landscape, with tumor growth depending on the cooperation of multiple driver mutations. While sequencing of tens of thousands of clinical samples has revealed a vast set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::899b0222484a93558c8dafd1de6a0783
https://doi.org/10.1158/1538-7445.am2023-1172
https://doi.org/10.1158/1538-7445.am2023-1172
Autor:
David Amar, Erick Scott, Ian P. Winters, Gregory D. Wall, Dmitri A. Petrov, Monte M. Winslow, Joseph Juan, Ian K. Lai, Lafia Sebastian, Edwin A. Apilado, Gabriel Grenot, Vy B. Tran, Charles Rudin, Michael J. Rosen
Publikováno v:
Cancer Research. 83:5723-5723
Recent development of therapies targeting oncogenes have dramatically improved cancer care for subsets of patients and generated a wave of interest in cancer precision medicine. However, effective targeted therapies are scarce as we have a limited un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::522bb2d49867a121490eb71cecb3ecf0
https://doi.org/10.1158/1538-7445.am2023-5723
https://doi.org/10.1158/1538-7445.am2023-5723
Autor:
Lily M. Blair, Joseph M. Juan, Lafia Sebastian, Vy B. Tran, Wensheng Nie, Gregory D. Wall, Mehmet Gerceker, Ian K. Lai, Edwin A. Apilado, Gabriel Grenot, David Amar, Giorgia Foggetti, Mariana Do Carmo, Zeynep Ugur, Debbie Deng, Alex Chenchik, Maria Paz Zafra, Lukas E. Dow, Katerina Politi, Jonathan J. MacQuitty, Dmitri A. Petrov, Monte M. Winslow, Michael J. Rosen, Ian P. Winters
Tumors acquire alterations in oncogenes and tumor suppressor genes in an adaptive walk through the fitness landscape of tumorigenesis. However, the features of this landscape remain poorly understood and cannot be revealed by human cancer genotyping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24eaf900600c609cefb81d012b1d1452
https://doi.org/10.1101/2022.10.24.511787
https://doi.org/10.1101/2022.10.24.511787
Autor:
Blair, Lily M., Juan, Joseph M., Sebastian, Lafia, Tran, Vy B., Nie, Wensheng, Wall, Gregory D., Gerceker, Mehmet, Lai, Ian K., Apilado, Edwin A., Grenot, Gabriel, Amar, David, Foggetti, Giorgia, Do Carmo, Mariana, Ugur, Zeynep, Deng, Debbie, Chenchik, Alex, Paz Zafra, Maria, Dow, Lukas E., Politi, Katerina, MacQuitty, Jonathan J.
Publikováno v:
Nature Communications; 10/12/2023, Vol. 14 Issue 1, p1-19, 19p