Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Edwin A, Yates"'
Autor:
Aleksandra Maria Kozlowski, Vlad Dinu, Thomas MacCalman, Alan Mark Smith, Johannes Peter Roubroeks, Edwin Alexander Yates, Stephen Ernest Harding, Gordon Alistair Morris
Publikováno v:
Polysaccharides, Vol 4, Iss 2, Pp 88-98 (2023)
This work evaluated the hydrodynamic properties of heparin hydrolysed at temperatures ranging from 40 °C to 80 °C in buffered acid and alkaline environments. The correlation between hydrodynamic parameters led to the conclusion that polymer conform
Externí odkaz:
https://doaj.org/article/ca702156d6e84745a70b9330dc6dda37
Autor:
Jessica M. Rustia, Judith P. Antonino, Ravelina R. Velasco, Marcelo A. Lima, Edwin A. Yates, David G. Fernig
Publikováno v:
Fishes, Vol 8, Iss 10, p 493 (2023)
The windowpane oyster Placuna placenta lives in brackish coastal waters and has long been economically important to the Philippines because of its durable and translucent shell, which is used as a glass substitute and material for making windowpanes
Externí odkaz:
https://doaj.org/article/feeb52a00d544feaaabb69d88caef443
Autor:
Anna L. Gray, Richard Karlsson, Abigail R.E. Roberts, Amanda J.L. Ridley, Nabina Pun, Bakhtbilland Khan, Craig Lawless, Rafael Luís, Martyna Szpakowska, Andy Chevigné, Catherine E. Hughes, Laura Medina-Ruiz, Holly L. Birchenough, Iashia Z. Mulholland, Catherina L. Salanga, Edwin A. Yates, Jeremy E. Turnbull, Tracy M. Handel, Gerard J. Graham, Thomas A. Jowitt, Ingo Schiessl, Ralf P. Richter, Rebecca L. Miller, Douglas P. Dyer
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111930- (2023)
Summary: Leukocyte recruitment from the vasculature into tissues is a crucial component of the immune system but is also key to inflammatory disease. Chemokines are central to this process but have yet to be therapeutically targeted during inflammati
Externí odkaz:
https://doaj.org/article/a86b22d342b64eea907a81850c7c8b16
Autor:
Susan L. Lindsay, Rebecca Sherrard Smith, Edwin A. Yates, Colin Cartwright, Bryan E. Thacker, Jeremy E. Turnbull, Charles A. Glass, Susan C. Barnett
Publikováno v:
Biology, Vol 12, Iss 3, p 407 (2023)
Therapies that target the multicellular pathology of central nervous system (CNS) disease/injury are urgently required. Modified non-anticoagulant heparins mimic the heparan sulphate (HS) glycan family and have been proposed as therapeutics for CNS r
Externí odkaz:
https://doaj.org/article/1e07cdcdee96451c90a68e210f467151
Autor:
Didier Ndeh, Arnaud Baslé, Henrik Strahl, Edwin A. Yates, Urszula L. McClurgg, Bernard Henrissat, Nicolas Terrapon, Alan Cartmell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Glycosaminoglycans (GAGs) are an important nutrient source for the gut microbiome. Here, the authors characterize the genetic loci that underpins glycosaminoglycan utilization in Bacteroides thetaiotaomicron; providing insights into the metabolism of
Externí odkaz:
https://doaj.org/article/688f5812d968451784c2da1237f3178e
Autor:
Courtney J Mycroft-West, Anthony J Devlin, Lynsay C Cooper, Patricia Procter, Gavin J Miller, David G Fernig, Marco Guerrini, Scott E Guimond, Marcelo A Lima, Edwin A Yates, Mark Andrew Skidmore
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 8, Pp 1546-1553 (2020)
The pharmaceutical and anticoagulant agent heparin, a member of the glycosaminoglycan family of carbohydrates, has previously been identified as a potent inhibitor of a key Alzheimer’s disease drug target, the primary neuronal β-secretase, β-site
Externí odkaz:
https://doaj.org/article/d30637bf9c56424598842f9e806a405d
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases. However, a simple and effective way in assessing galectin-ligand
Externí odkaz:
https://doaj.org/article/030c40846b0749f9815431bef71e56dd
Autor:
Changye Sun, Mengxin Liu, Panwen Sun, Mingming Yang, Edwin A. Yates, Zhikun Guo, David G. Fernig
Publikováno v:
FEBS Open Bio, Vol 9, Iss 8, Pp 1477-1487 (2019)
Fibroblast growth factors (FGFs) regulate embryonic development and homeostasis, including tissue and organ repair and specific aspects of metabolism. The basic FGF and acidic FGF, now known as FGF2 and FGF1, are widely used protein drugs for tissue
Externí odkaz:
https://doaj.org/article/eb45c05452324b728998c57b92881765
Publikováno v:
Essays in Biochemistry. 67:429-442
Sulfated host glycans (mucin O-glycans and glycosaminoglycans [GAGs]) are critical nutrient sources and colonisation factors for Bacteroidetes of the human gut microbiota (HGM); a complex ecosystem comprising essential microorganisms that coevolved w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ce381d53c27656b7cf0a335d13c072
https://doi.org/10.1042/ebc20220120
https://doi.org/10.1042/ebc20220120
Autor:
Susan L. Lindsay, George A. McCanney, Jiangshan Zhan, Miriam Scheld, Rebecca Sherrard Smith, Carl S. Goodyear, Edwin A. Yates, Markus Kipp, Jeremy E. Turnbull, Susan C. Barnett
Publikováno v:
Glia. 71:1683-1698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bf33ecea7da0600ae67df362d5f4a25
https://doi.org/10.1002/glia.24363
https://doi.org/10.1002/glia.24363