Zobrazeno 1 - 10
of 602
pro vyhledávání: '"Edwin A, Deitch"'
Autor:
Diego C Reino, Vadim Pisarenko, David Palange, Danielle Doucet, Robert P Bonitz, Qi Lu, Iriana Colorado, Sharvil U Sheth, Benjamin Chandler, Kolenkode B Kannan, Madhuri Ramanathan, Da Zhong Xu, Edwin A Deitch, Rena Feinman
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e14829 (2011)
BackgroundInjurious non-microbial factors released from the stressed gut during shocked states contribute to the development of acute lung injury (ALI) and multiple organ dysfunction syndrome (MODS). Since Toll-like receptors (TLR) act as sensors of
Externí odkaz:
https://doaj.org/article/14c935ccf42d4031b16d9051dee8602b
Autor:
Danielle Doucet, Chirag Badami, David Palange, R Paul Bonitz, Qi Lu, Da-Zhong Xu, Kolenkode B Kannan, Iriana Colorado, Rena Feinman, Edwin A Deitch
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9421 (2010)
Acute lung injury (ALI) and the development of the multiple organ dysfunction syndrome (MODS) is a major cause of death in trauma patients. Earlier studies in trauma hemorrhagic shock (T/HS) have documented that splanchnic ischemia leading to gut inf
Externí odkaz:
https://doaj.org/article/f4d080df77894a15be0efd7dfe77e2b3
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
The inflammatory responses in sepsis and hemorrhage remain a major cause of death. Clinically, it is generally accepted that shock in sepsis or hemorrhage differs in its mechanisms. However, the recognition of inflammatory cytokines as a common letha
Externí odkaz:
https://doaj.org/article/499504f5bce14b8b94815a4e3977a64b
Autor:
Balázs Csóka, Zoltán H Németh, Partha Mukhopadhyay, Zoltán Spolarics, Mohanraj Rajesh, Stephanie Federici, Edwin A Deitch, Sándor Bátkai, Pál Pacher, György Haskó
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6409 (2009)
BACKGROUND:Sepsis is a major healthcare problem and current estimates suggest that the incidence of sepsis is approximately 750,000 annually. Sepsis is caused by an inability of the immune system to eliminate invading pathogens. It was recently propo
Externí odkaz:
https://doaj.org/article/00cf65ea0c4f4255ba7d4f9cd06718c3
Autor:
Vamsi Alli, Da-Zhong Xu, Gal Levy, Xiaofa Qin, Sharvil U. Sheth, Edwin A. Deitch, Yung Qin, Jordan E. Fishman, Qu Lu
Publikováno v:
Annals of Surgery. 260:1112-1120
To test whether the mucus layer, luminal digestive enzymes, and intestinal mast cells are critical components in the pathogenesis of trauma shock-induced gut and lung injury.Gut origin sepsis studies have highlighted the importance of the systemic co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea006dd81485779945814205a49caa2
https://doi.org/10.1097/sla.0000000000000631
https://doi.org/10.1097/sla.0000000000000631
Autor:
Julie Y. Son, Benjamin Chandler, Yong Qin, Eleonora Feketeova, Lauriston M. Prescott, Joyce A. Bonitz, Edwin A. Deitch, Jacquelyn N. Tomaio
Publikováno v:
Shock. 42:448-455
Trauma/hemorrhagic shock (T/HS) is one of the major consequences of battlefield injury as well as civilian trauma. FTY720 (sphingosine-1-phosphate agonist) has the capability to decrease the activity of the innate and adaptive immune systems and, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09151888de1f310395338d5d17bfd4d
https://doi.org/10.1097/shk.0000000000000227
https://doi.org/10.1097/shk.0000000000000227
Autor:
Elizabeth J. Quackenbush, Julie Y. Son, Benjamin Chandler, Yung Qin, Eleonora Feketova, Edwin A. Deitch
Publikováno v:
Journal of Surgical Research. 187:270-277
Background Lactoferrin (LF) is a pleiotropic glycoprotein that is found in bodily secretions and is postulated to enhance the gastrointestinal barrier and promote mucosal immunity. Thus, the ability of talactoferrin, an oral recombinant form of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0f77d704bf99f0ae7b2b7234fe603d
https://doi.org/10.1016/j.jss.2013.10.026
https://doi.org/10.1016/j.jss.2013.10.026
Publikováno v:
Journal of Surgical Research. 183:678-685
Background Myocardial contractile depression develops 4 to 24 h after major burn injury. We have reported previously that in a rat burn injury model (≈40% of total body surface area burn), mesenteric lymph duct ligation (LDL) prior to burn prevente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3788a5704006ddbfdc5198d606ef7385
https://doi.org/10.1016/j.jss.2013.01.065
https://doi.org/10.1016/j.jss.2013.01.065
Autor:
James A. Thomas, Tripti Bishwas, Rachna Chandra, Zoltán Németh, Zoltán Spolarics, Stephanie Federici, Edwin A. Deitch
Publikováno v:
Inflammation. 36:1503-1512
Interleukin-1 receptor-associated kinase (IRAK1) is a key regulatory protein in TLR/IL1R-mediated cell activation during inflammatory response. Studies indicated that pending on the nature of the used inflammatory model, downregulation of IRAK1 may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8da288df111d0d8a13eb200213c35b
https://doi.org/10.1007/s10753-013-9692-1
https://doi.org/10.1007/s10753-013-9692-1
Autor:
Jacquelyn N. Tomaio, Edwin A. Deitch, Leonard Mason, David Palange, Gregory Tiesi, Diego Reino
Publikováno v:
Shock. 39:507-513
Immune depression after trauma-hemorrhage has been implicated as an important factor in the pathogenesis of sepsis and septic-organ failure. Although recent studies have implicated immune-cell apoptosis as an important factor in the evolution of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0ee18a19bd216dd72023adcfc608aff
https://doi.org/10.1097/shk.0b013e318293d020
https://doi.org/10.1097/shk.0b013e318293d020