Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Edwin, Vedejs"'
Publikováno v:
The Journal of Organic Chemistry. 82:12757-12762
Tetrahydro-1,4-azaborines were accessed by hydroboration of N,N-diprenyltoluenesulfonamide 4. Conversion to the methylborinates 11 and 12 followed by heating with l-alanine and crystallization afforded (R,R,S)-13 (27%). Reduction of borinic acid (R,R
Publikováno v:
The Journal of Organic Chemistry. 82:869-886
A new catalyst for the dynamic kinetic resolution of azole hemiaminals has been developed using late-stage structural modifications of the tert-leucinol-derived chiral subunit of DMAP species.
Publikováno v:
The Journal of organic chemistry. 82(23)
Tetrahydro-1,4-azaborines were accessed by hydroboration of N,N-diprenyltoluenesulfonamide 4. Conversion to the methylborinates 11 and 12 followed by heating with l-alanine and crystallization afforded (R,R,S)-13 (27%). Reduction of borinic acid (R,R
Publikováno v:
Chemistry of Heterocyclic Compounds. 51:613-620
Benzofuro[2,3-b]indolines undergo ring opening in the presence of base to generate 3H-indolines. The latter can rearrange into 3-arylindoles through an intramolecular transfer of the methoxycarbonyl moiety from quaternary carbon to oxygen of phenol.
Autor:
Edwin Vedejs
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 190:612-618
Autor:
Edwin Vedejs, Gorka Peris
Publikováno v:
The Journal of Organic Chemistry. 80:3050-3057
A chiral benzylic ether serves as an auxiliary for oxindole carboxylation (dr 5.2:1.0) that sets C10 configuration in a potential diazonamide precursor. The chiral substituent allows diastereomer separation and departs during a subsequent acid-cataly
Publikováno v:
Organometallics. 32:6701-6711
Catalytic procedures are described for the amine-directed borylation of aliphatic and aromatic tertiary amine–boranes. Sequential double borylation is observed in cases where two or more C–H bonds are available that allow 5-center or 6-center int
Autor:
Edwin Vedejs, Scott E. Denmark
This three-volume set represents the first comprehensive coverage of the rapidly expanding field of Lewis base catalysis that has attracted enormous attention in recent years. Lewis base catalysis is a conceptually novel paradigm that encompasses an
Autor:
Naresh Theddu, Edwin Vedejs
Publikováno v:
The Journal of Organic Chemistry. 78:5061-5066
An aziridinyl stannatrane 8 couples with aryl or alkenyl halides RX under modified Stille conditions to afford substituted aziridines. Efficient coupling at room temperature is possible in the best examples in the presence of ((t)Bu3P)2Pd and CuOP(O)
Publikováno v:
Organic Letters. 15:984-987
Internal borylation occurs upon activation of aryl di-isopropylphosphinite boranes with HNTf(2) to give heterocyclic intermediates that can be reductively quenched to afford 6 or treated with KHF(2) to give the phenolic potassium aryl trifluoroborate