Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Edwin, Lasonder"'
Autor:
Jemma Dunn, Sara Ferluga, Vikram Sharma, Matthias Futschik, David A. Hilton, Claire L. Adams, Edwin Lasonder, C. Oliver Hanemann
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 77-91 (2019)
Background: Meningioma is the most frequent primary intracranial tumour. Surgical resection remains the main therapeutic option as pharmacological intervention is hampered by poor knowledge of their proteomic signature. There is an urgent need to ide
Externí odkaz:
https://doaj.org/article/941610315eae44c99a420e489e4450af
Autor:
Edwin Lasonder, Kunal More, Shailja Singh, Malak Haidar, Daniela Bertinetti, Eileen J. Kennedy, Friedrich W. Herberg, Anthony A. Holder, Gordon Langsley, Chetan E. Chitnis
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
We review the role of signaling pathways in regulation of the key processes of merozoite egress and red blood cell invasion by Plasmodium falciparum and, in particular, the importance of the second messengers, cAMP and Ca2+, and cyclic nucleotide dep
Externí odkaz:
https://doaj.org/article/de12574100264a50a9905dfa1595a22b
Autor:
Judith L Green, Yang Wu, Vesela Encheva, Edwin Lasonder, Adchara Prommaban, Simone Kunzelmann, Evangelos Christodoulou, Munira Grainger, Ngoc Truongvan, Sebastian Bothe, Vikram Sharma, Wei Song, Irene Pinzuti, Chairat Uthaipibull, Somdet Srichairatanakool, Veronique Birault, Gordon Langsley, Hermann Schindelin, Benjamin Stieglitz, Ambrosius P Snijders, Anthony A Holder
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008640 (2020)
Ubiquitylation is a common post translational modification of eukaryotic proteins and in the human malaria parasite, Plasmodium falciparum (Pf) overall ubiquitylation increases in the transition from intracellular schizont to extracellular merozoite
Externí odkaz:
https://doaj.org/article/02cebcacd3f549579a7e6b82f7f59588
Autor:
Will J. R. Stone, Joseph J. Campo, André Lin Ouédraogo, Lisette Meerstein-Kessel, Isabelle Morlais, Dari Da, Anna Cohuet, Sandrine Nsango, Colin J. Sutherland, Marga van de Vegte-Bolmer, Rianne Siebelink-Stoter, Geert-Jan van Gemert, Wouter Graumans, Kjerstin Lanke, Adam D. Shandling, Jozelyn V. Pablo, Andy A. Teng, Sophie Jones, Roos M. de Jong, Amanda Fabra-García, John Bradley, Will Roeffen, Edwin Lasonder, Giuliana Gremo, Evelin Schwarzer, Chris J. Janse, Susheel K. Singh, Michael Theisen, Phil Felgner, Matthias Marti, Chris Drakeley, Robert Sauerwein, Teun Bousema, Matthijs M. Jore
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Naturally acquired antibodies may inhibit Plasmodium survival in mosquitoes, alter malaria transmission dynamics, and form the basis for transmission-blocking vaccines. Here, using sera from malaria-exposed individuals, Stone et al. reveal novel anti
Externí odkaz:
https://doaj.org/article/a727fd054ca84e01a19890f2a0ecb7bd
Autor:
Kayleigh Bassiri, Sara Ferluga, Vikram Sharma, Nelofer Syed, Claire L. Adams, Edwin Lasonder, C Oliver Hanemann
Publikováno v:
EBioMedicine, Vol 16, Iss C, Pp 76-86 (2017)
Loss or mutation of the tumour suppressor Merlin predisposes individuals to develop multiple nervous system tumours, including schwannomas and meningiomas, sporadically or as part of the autosomal dominant inherited condition Neurofibromatosis 2 (NF2
Externí odkaz:
https://doaj.org/article/97a6ab91e9e9455ebe8926c7df51adf3
Autor:
Will J. R. Stone, Joseph J. Campo, André Lin Ouédraogo, Lisette Meerstein-Kessel, Isabelle Morlais, Dari Da, Anna Cohuet, Sandrine Nsango, Colin J. Sutherland, Marga van de Vegte-Bolmer, Rianne Siebelink-Stoter, Geert-Jan van Gemert, Wouter Graumans, Kjerstin Lanke, Adam D. Shandling, Jozelyn V. Pablo, Andy A. Teng, Sophie Jones, Roos M. de Jong, Amanda Fabra-García, John Bradley, Will Roeffen, Edwin Lasonder, Giuliana Gremo, Evelin Schwarzer, Chris J. Janse, Susheel K. Singh, Michael Theisen, Phil Felgner, Matthias Marti, Chris Drakeley, Robert Sauerwein, Teun Bousema, Matthijs M. Jore
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-3 (2018)
The original version of this Article contained errors in Fig. 3. In panel a, bars from a chart depicting the percentage of antibody-positive individuals in non-infectious and infectious groups were inadvertently included in place of bars depicting th
Externí odkaz:
https://doaj.org/article/30ee120b12154d96a3c57ed32039d0e8
Autor:
Kuntal Worah, Till S.M. Mathan, Thien Phong Vu Manh, Shivakumar Keerthikumar, Gerty Schreibelt, Jurjen Tel, Tjitske Duiveman-de Boer, Annette E. Sköld, Annemiek B. van Spriel, I. Jolanda M. de Vries, Martijn A. Huynen, Hans J. Wessels, Jolein Gloerich, Marc Dalod, Edwin Lasonder, Carl G. Figdor, Sonja I. Buschow
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2953-2966 (2016)
Dendritic cells (DCs) play a key role in orchestrating adaptive immune responses. In human blood, three distinct subsets exist: plasmacytoid DCs (pDCs) and BDCA3+ and CD1c+ myeloid DCs. In addition, a DC-like CD16+ monocyte has been reported. Althoug
Externí odkaz:
https://doaj.org/article/99bcaf49949f4c9db41b1a9bdec4e4f1
Autor:
Joames K. Freitas Leal, Edwin Lasonder, Vikram Sharma, Jürgen Schiller, Giuseppina Fanelli, Sara Rinalducci, Roland Brock, Giel Bosman
Publikováno v:
Proteomes, Vol 8, Iss 2, p 6 (2020)
Microvesicle generation is an integral part of the aging process of red blood cells in vivo and in vitro. Extensive vesiculation impairs function and survival of red blood cells after transfusion, and microvesicles contribute to transfusion reactions
Externí odkaz:
https://doaj.org/article/cba9a3aa44ad49d4b8ddc09facf3b71e
Autor:
Christina Eich, Edwin Lasonder, Luis J Cruz, Inge Reinieren-Beeren, Alessandra Cambi, Carl G Figdor, Sonja I Buschow
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149637 (2016)
The β2-integrin lymphocyte function-associated antigen 1 (LFA-1) plays an important role in the migration, adhesion and intercellular communication of dendritic cells (DCs). During the differentiation of human DCs from monocyte precursors, LFA-1 lig
Externí odkaz:
https://doaj.org/article/dbb93c3fc6af40d98b2b7f89829272ea
Autor:
Edwin Lasonder, Claire L. Adams, Sara Ferluga, Jemma Dunn, Vikram Sharma, C. Oliver Hanemann, David A Hilton, Matthias E. Futschik
Publikováno v:
EBioMedicine, Vol 40, Iss, Pp 77-91 (2019)
EBioMedicine
EBioMedicine
Background: Meningioma is the most frequent primary intracranial tumour. Surgical resection remains the main therapeutic option as pharmacological intervention is hampered by poor knowledge of their proteomic signature. There is an urgent need to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a333565337fa9bc79aea97216f5f4a
https://doi.org/10.1016/j.ebiom.2018.12.048
https://doi.org/10.1016/j.ebiom.2018.12.048