Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Edwige Belotti"'
Autor:
Alexis Osseni, Aymeric Ravel-Chapuis, Edwige Belotti, Isabella Scionti, Yann-Gaël Gangloff, Vincent Moncollin, Laetitia Mazelin, Remi Mounier, Pascal Leblanc, Bernard J. Jasmin, Laurent Schaeffer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, authors show that Smad3 acetylation via HDAC6 inhibition reverses Duchenne muscular dystrophy-like symptoms in the mdx mouse model, suggesting a potential therapeutic target for the disorder.
Externí odkaz:
https://doaj.org/article/cdf9d7e3e2ad4da9b5e4aa9491b771ee
Autor:
Arnaud Jacquier, Cécile Delorme, Edwige Belotti, Raoul Juntas-Morales, Guilhem Solé, Odile Dubourg, Marianne Giroux, Claude-Alain Maurage, Valérie Castellani, Adriana Rebelo, Alexander Abrams, Stephan Züchner, Tanya Stojkovic, Laurent Schaeffer, Philippe Latour
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-15 (2017)
Abstract Neurofilament heavy chain (NEFH) gene was recently identified to cause autosomal dominant axonal Charcot-Marie-Tooth disease (CMT2cc). However, the clinical spectrum of this condition and the physio-pathological pathway remain to be delineat
Externí odkaz:
https://doaj.org/article/ae14d115f55646d6af208f47cc1be8d2
Autor:
Tania M. Puvirajesinghe, François Bertucci, Ashish Jain, Pierluigi Scerbo, Edwige Belotti, Stéphane Audebert, Michael Sebbagh, Marc Lopez, Andreas Brech, Pascal Finetti, Emmanuelle Charafe-Jauffret, Max Chaffanet, Rémy Castellano, Audrey Restouin, Sylvie Marchetto, Yves Collette, Anthony Gonçalvès, Ian Macara, Daniel Birnbaum, Laurent Kodjabachian, Terje Johansen, Jean-Paul Borg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeuti
Externí odkaz:
https://doaj.org/article/613bb808db014e17b9b94d6f70ddaa1f
Autor:
Edwige Belotti, Tania M Puvirajesinghe, Stéphane Audebert, Emilie Baudelet, Luc Camoin, Michel Pierres, Lea Lasvaux, Géraldine Ferracci, Mireille Montcouquiol, Jean-Paul Borg
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46213 (2012)
BackgroundMutations in the Planar Cell Polarity (PCP) core gene Vangl2 cause the most severe neural tube defects (NTD) in mice and humans. Genetic studies show that the Vangl2 gene genetically interacts with a close homologue Vangl1. How precisely Va
Externí odkaz:
https://doaj.org/article/87709adb080a4559b31b0d6be284f9a3
Autor:
Edwige Belotti, Laurent Schaeffer
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2020, 735, pp.135163-. ⟨10.1016/j.neulet.2020.135163⟩
Neuroscience Letters, 2020, 735, pp.135163-. ⟨10.1016/j.neulet.2020.135163⟩
Neuroscience Letters, Elsevier, 2020, 735, pp.135163-. ⟨10.1016/j.neulet.2020.135163⟩
Neuroscience Letters, 2020, 735, pp.135163-. ⟨10.1016/j.neulet.2020.135163⟩
Gene expression in skeletal muscle is profoundly changed upon innervation. 50 years of research on the neuromuscular system have greatly increased our understanding of the mechanisms underlying these changes. By controlling the expression and the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c571e10303523038d6aad1524471c9f
https://hal.archives-ouvertes.fr/hal-03490863
https://hal.archives-ouvertes.fr/hal-03490863
Autor:
Kiran Padmanabhan, Ali Hamiche, Stefan Dimitrov, Lorrie Ramos, Christophe Papin, Defne Dalkara, Yann-Gaël Gangloff, Nicolas Lacoste, Isabella Scionti, Laurent Schaeffer, Edwige Belotti, Thomas Simonet
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2020, 48, pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, Oxford University Press, 2020, 48, pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
Nucleic Acids Research, 2020, 48 (9), pp.4601-4613. ⟨10.1093/nar/gkaa157⟩
While the histone variant H2A.Z is known to be required for mitosis, it is also enriched in nucleosomes surrounding the transcription start site of active promoters, implicating H2A.Z in transcription. However, evidence obtained so far mainly rely on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30b351fbc8d2bed8599301df8df7928
https://avesis.deu.edu.tr/publication/details/0ffef56b-2c9f-4f12-82bb-0b9bd2ad8259/oai
https://avesis.deu.edu.tr/publication/details/0ffef56b-2c9f-4f12-82bb-0b9bd2ad8259/oai
Autor:
Valérie Castellani, Edwige Belotti, Alexander J. Abrams, Laurent Schaeffer, Claude Alain Maurage, Tanya Stojkovic, Arnaud Jacquier, Philippe Latour, Guilhem Solé, Cécile Delorme, Marianne Giroux, Odile Dubourg, Adriana P. Rebelo, Stephan Züchner, Raoul Juntas-Morales
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-15 (2017)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Neurofilament heavy chain (NEFH) gene was recently identified to cause autosomal dominant axonal Charcot-Marie-Tooth disease (CMT2cc). However, the clinical spectrum of this condition and the physio-pathological pathway remain to be delineated. We re
Autor:
Thomas Simonet, Kiran Padmanabhan, Defne Dalkara, Ali Hamiche, Stefan Dimitrov, Nicolas Lacoste, Laurent Schaeffer, Edwige Belotti, Isabella Scionti, Lorrie Ramos, Christophe Papin
The histone variant H2A.Z is enriched in nucleosomes surrounding the transcription start site of active promoters, suggesting that it might be implicated in transcription. It is also required during mitosis. However, evidences obtained so far mainly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19eca95cc5b72634f6fec120cd483310
https://doi.org/10.1101/823526
https://doi.org/10.1101/823526
Autor:
Geoffrey Teixeira, Emilie Delaune, Qing Zhang, Théophile Ohlmann, Daniel Taillandier, Laetitia Mazelin, Michel Ovize, Anne-Sophie Nicot, Baptiste Panthu, Yann-Gaël Gangloff, Geneviève Derumeaux, Lionel A. Tintignac, Laurent Schaeffer, Edwige Belotti, Dominique Baas, Valérie Risson
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2016, 97, pp.213-225. ⟨10.1016/j.yjmcc.2016.04.011⟩
Journal of Molecular and Cellular Cardiology, 2016, 97, pp.213-225. ⟨10.1016/j.yjmcc.2016.04.011⟩
Journal of Molecular and Cellular Cardiology, Elsevier, 2016, 97, pp.213-225. ⟨10.1016/j.yjmcc.2016.04.011⟩
Journal of Molecular and Cellular Cardiology, 2016, 97, pp.213-225. ⟨10.1016/j.yjmcc.2016.04.011⟩
Mechanistic target of rapamycin (mTOR) is a central regulator of cell growth, proliferation, survival and metabolism, as part of mTOR complex 1 (mTORC1) and mTORC2. While partial inhibition of mTORC1 using rapamycin was shown to be cardioprotective,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88b644a111b9891ef38f69bb11d2d83
https://hal.archives-ouvertes.fr/hal-01837643
https://hal.archives-ouvertes.fr/hal-01837643
Autor:
Michael Sebbagh, Anthony Gonçalves, Yves Collette, Ashish Jain, Max Chaffanet, Laurent Kodjabachian, Marc Lopez, Andreas Brech, Sylvie Marchetto, Jean-Paul Borg, Audrey Restouin, Pierluigi Scerbo, Terje Johansen, Daniel Birnbaum, Stéphane Audebert, Pascal Finetti, Edwige Belotti, Tania M. Puvirajesinghe, Emmanuelle Charafe-Jauffret, François Bertucci, Rémy Castellano, Ian G. Macara
Publikováno v:
Nature Communications
Nature Communications, 2016, 7, pp.10318. ⟨10.1038/ncomms10318⟩
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Nature Publishing Group, 2016, 7, pp.10318. ⟨10.1038/ncomms10318⟩
Nature Communications, 2016, 7, pp.10318. ⟨10.1038/ncomms10318⟩
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Nature Publishing Group, 2016, 7, pp.10318. ⟨10.1038/ncomms10318⟩
The non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway plays a crucial role in embryonic development. Recent work has linked defects of this pathway to breast cancer aggressiveness and proposed Wnt/PCP signalling as a therapeutic target. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af77425d3026375cd9e0705af022f4e
https://hal.science/hal-01447570/file/Identification_of_p62SQSTM1_as_a_component_of_non-.pdf
https://hal.science/hal-01447570/file/Identification_of_p62SQSTM1_as_a_component_of_non-.pdf