Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Edwige Abeilard"'
Autor:
Lucie Thorel, Pierre-Marie Morice, Hippolyte Paysant, Romane Florent, Guillaume Babin, Cécilia Thomine, Marion Perréard, Edwige Abeilard, Florence Giffard, Emilie Brotin, Christophe Denoyelle, Céline Villenet, Shéhérazade Sebda, Mélanie Briand, Florence Joly, Enora Dolivet, Didier Goux, Cécile Blanc-Fournier, Corinne Jeanne, Marie Villedieu, Matthieu Meryet-Figuiere, Martin Figeac, Laurent Poulain, Louis-Bastien Weiswald
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background In the era of personalized medicine, the establishment of preclinical models of cancer that faithfully recapitulate original tumors is essential to potentially guide clinical decisions. Methods We established 7 models [4 cell line
Externí odkaz:
https://doaj.org/article/fcc6d93e6e1648e1ac7194108ee99a59
Autor:
Anaïs Wambecke, Mohammad Ahmad, Pierre‐Marie Morice, Bernard Lambert, Louis‐Bastien Weiswald, Mégane Vernon, Nicolas Vigneron, Edwige Abeilard, Emilie Brotin, Martin Figeac, Pascal Gauduchon, Laurent Poulain, Christophe Denoyelle, Matthieu Meryet‐Figuiere
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3659-3678 (2021)
Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due to late diagnosis and resistance to chemotherapy, the 5‐year survival rate in patients with OC is below 40%. We observed that UCA1, a lncRNA previously repo
Externí odkaz:
https://doaj.org/article/8a1e4e42fbc5491cb25a6a66c4690349
Autor:
Matthieu Meryet-Figuiere, Mégane Vernon, Mamy Andrianteranagna, Bernard Lambert, Célia Brochen, Jean-Paul Issartel, Audrey Guttin, Pascal Gauduchon, Emilie Brotin, Florent Dingli, Damarys Loew, Nicolas Vigneron, Anaïs Wambecke, Edwige Abeilard, Emmanuel Barillot, Laurent Poulain, Loredana Martignetti, Christophe Denoyelle
Publikováno v:
Cancers, Vol 13, Iss 16, p 3970 (2021)
The identification of miRNAs’ targets and associated regulatory networks might allow the definition of new strategies using drugs whose association mimics a given miRNA’s effects. Based on this assumption we devised a multi-omics approach to prec
Externí odkaz:
https://doaj.org/article/11e926ab40b840498bae9039620f1c7c
Autor:
Christophe Denoyelle, Laurent Poulain, Pascal Gauduchon, Cécile Blanc-Fournier, Marie-Hélène Louis, Florence Giffard, Edwige Abeilard, Anaïs Wambecke, Nicolas Vigneron, Hippolyte Paysant, Louis-Bastien Weiswald, Emilie Brotin, Matthieu Meryet-Figuière, Bernard Lambert, Mégane Vernon
Novel therapeutic strategies are urgently required for the clinical management of chemoresistant ovarian carcinoma, which is the most lethal of the gynecologic malignancies. miRNAs hold promise because they play a critical role in determining the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e171fe93114453568b49b67d90e86f8
https://doi.org/10.1158/1535-7163.c.6542257
https://doi.org/10.1158/1535-7163.c.6542257
Autor:
Christophe Denoyelle, Pascal Gauduchon, Martin Figeac, Emilie Brotin, Nicolas Vigneron, Louis-Bastien Weiswald, Anaïs Wambecke, Mégane Vernon, Laurent Poulain, Mohammad Ahmad, Matthieu Meryet-Figuière, Edwige Abeilard, Bernard Lambert, Pierre-Marie Morice
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 15, Iss 12, Pp 3659-3678 (2021)
Molecular Oncology, Vol 15, Iss 12, Pp 3659-3678 (2021)
Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due to late diagnosis and resistance to chemotherapy, the 5‐year survival rate in patients with OC is below 40%. We observed that UCA1, a lncRNA previously repo
Autor:
Nicolas Vigneron, Pierre-Marie Morice, Mohammad Ahmad, Pascal Gauduchon, Mégane Vernon, Emilie Brotin, Laurent Poulain, Louis-Bastien Weiswald, Edwige Abeilard, Anaïs Wambecke, Christophe Denoyelle, Matthieu Meryet-Figuière, Bernard Lambert, Martin Figeac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea50e48480c67ced552d53ca01f9ca10
https://doi.org/10.1002/1878-0261.13045/v2/response1
https://doi.org/10.1002/1878-0261.13045/v2/response1
Autor:
Mamy Andrianteranagna, Emilie Brotin, Emmanuel Barillot, Mégane Vernon, Edwige Abeilard, Loredana Martignetti, Nicolas Vigneron, Jean-Paul Issartel, Damarys Loew, Célia Brochen, Anaïs Wambecke, Matthieu Meryet-Figuière, Florent Dingli, Pascal Gauduchon, Audrey Guttin, Christophe Denoyelle, Laurent Poulain, Bernard Lambert
Publikováno v:
Cancers, Vol 13, Iss 3970, p 3970 (2021)
Cancers
Volume 13
Issue 16
Cancers
Volume 13
Issue 16
Simple Summary The re-introduction of miRNAs with tumor-suppressor activity in cancer cells has not yet been implemented in clinical practice yet. However, the identification of miRNAs’ targets and associated regulatory networks might allow the def
Autor:
Charlène Duboc, Laurent Poulain, Marie-Hélène Louis, Edwige Abeilard, Marie Villedieu, Christophe Denoyelle, Pascal Gauduchon, Cécile Pétigny-Lechartier, Abdelghani Jebahi
Publikováno v:
Molecular Cancer Therapeutics. 16:102-115
The identification of novel therapeutic strategies is an important urgent requirement for the clinical management of ovarian cancer, which remains the leading cause of death from gynecologic cancer. Several studies have shown that the antiapoptotic p
Autor:
Mor Sény Gueye, Laurent Poulain, Florence Giffard, Monique N'Diaye, Bernard Lambert, Marie-Hélène Louis, Edwige Abeilard, Emilie Brotin, Pascal Gauduchon, Marie-Laure Bonnefond
Publikováno v:
Apoptosis
Ovarian carcinoma is the leading cause of death from gynecologic cancer in the developed world and is characterized by acquired chemoresistance leading to an overall 5-year survival rate of about 30 %. We previously showed that Bcl-xL and Mcl-1 coope
Autor:
Marie-Laure, Bonnefond, Romane, Florent, Sophie, Lenoir, Bernard, Lambert, Edwige, Abeilard, Florence, Giffard, Marie-Hélène, Louis, Nicolas, Elie, Mélanie, Briand, Denis, Vivien, Laurent, Poulain, Pascal, Gauduchon, Monique, N'Diaye
Publikováno v:
Oncotarget
The anti-apoptotic proteins Bcl-xL and Mcl-1 have been identified to play a pivotal role in apoptosis resistance in ovarian cancer and constitute key targets for innovative therapeutic strategies. Although BH3-mimetics (i.e. ABT-737) potently inhibit