Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Edward W. Yu"'
Publikováno v:
PLoS Biology, Vol 22, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/77ee91d55afe41d499d4f3ce5acd2fe0
Autor:
Kristy Rochon, Brianna L. Bauer, Nathaniel A. Roethler, Yuli Buckley, Chih-Chia Su, Wei Huang, Rajesh Ramachandran, Maria S. K. Stoll, Edward W. Yu, Derek J. Taylor, Jason A. Mears
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Mitochondrial fission is a critical cellular event to maintain organelle function. This multistep process is initiated by the enhanced recruitment and oligomerization of dynamin-related protein 1 (Drp1) at the surface of mitochondria. As suc
Externí odkaz:
https://doaj.org/article/055fe09cab0743d7a3e11495314fac76
Autor:
Meranda M. Masse, Rachel B. Hutchinson, Christopher E. Morgan, Heather J. Allaman, Hongqing Guan, Edward W. Yu, Silvia Cavagnero
Publikováno v:
ACS Central Science, Vol 10, Iss 2, Pp 385-401 (2024)
Externí odkaz:
https://doaj.org/article/fe084fcd321b4364800f60a8496315f7
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Campylobacter jejuni is a foodborne pathogen commonly found in the intestinal tracts of animals. This pathogen is a leading cause of gastroenteritis in humans. Besides its highly infectious nature, C. jejuni is increasingly resistant to a nu
Externí odkaz:
https://doaj.org/article/1960bd5b3d974e089cbcfee1ed3e751d
Autor:
Samual C. Allgood, Chih-Chia Su, Amy L. Crooks, Christian T. Meyer, Bojun Zhou, Meredith D. Betterton, Michael R. Barbachyn, Edward W. Yu, Corrella S. Detweiler
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTNew approaches for combating microbial infections are needed. One strategy for disrupting pathogenesis involves developing compounds that interfere with bacterial virulence. A critical molecular determinant of virulence for Gram-negative bact
Externí odkaz:
https://doaj.org/article/c39352faf2c44a41aedbedba1f9e7998
Autor:
Zhemin Zhang, Nicholas Lizer, Zuowei Wu, Christopher E. Morgan, Yuqi Yan, Qijing Zhang, Edward W. Yu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Campylobacter jejuni is a bacterium that is commonly present in the intestinal tracts of animals. It is also a major foodborne pathogen that causes gastroenteritis in humans. The most predominant and clinically important multidrug efflux sys
Externí odkaz:
https://doaj.org/article/700874412bb6467ea83f6d28db7b91ca
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT The continued challenges of the COVID-19 pandemic combined with the growing problem of antimicrobial-resistant bacterial infections has severely impacted global health. Specifically, the Gram-negative pathogen Klebsiella pneumoniae is one of
Externí odkaz:
https://doaj.org/article/f13fd0e9153c4ce5aa6dde24dead76f8
Autor:
Chih-Chia Su, Meinan Lyu, Zhemin Zhang, Masaru Miyagi, Wei Huang, Derek J. Taylor, Edward W. Yu
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112609- (2023)
Summary: We applied raw human liver microsome lysate to a holey carbon grid and used cryo-electron microscopy (cryo-EM) to define its composition. From this sample we identified and simultaneously determined high-resolution structural information for
Externí odkaz:
https://doaj.org/article/c332cee5b6a040d4929941c9dbb12793
Autor:
Alex B. Green, Lucius Chiaraviglio, Katherine A. Truelson, Katelyn E. Zulauf, Meng Cui, Zhemin Zhang, Matthew P. Ware, Willy A. Flegel, Richard L. Haspel, Edward W. Yu, James E. Kirby
Publikováno v:
mSphere, Vol 8, Iss 2 (2023)
ABSTRACT Pathogen inactivation is a strategy to improve the safety of transfusion products. The only pathogen reduction technology for blood products currently approved in the US utilizes a psoralen compound, called amotosalen, in combination with UV
Externí odkaz:
https://doaj.org/article/153ae5941d124f1e9be09b96442b2e81
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT The Escherichia coli acriflavine resistance protein D (AcrD) is an efflux pump that belongs to the resistance-nodulation-cell division (RND) superfamily. Its primary function is to provide resistance to aminoglycoside-based drugs by actively
Externí odkaz:
https://doaj.org/article/894a2d9bd34641de91272b8cd7658c90