Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Edward W. Towers"'
Autor:
Xichdao Nguyen, Linda O. Narhi, John P. Gabrielson, Yijia Jiang, Salman Muzammil, Cynthia Li, Edward W. Towers
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4631-4641
Fourier transform infrared (FTIR) spectroscopy is widely used to study protein secondary structure both in solution and in the solid state. The FTIR spectroscopic method has also been employed as a characterization method by the biopharmaceutical ind
Autor:
Yijia Jiang, Edward W. Towers, Letha Chemmalil, John P. Gabrielson, Salman Muzammil, Cynthia Li, Xichdao Nguyen, Linda O. Narhi
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4642-4654
Circular dichroism (CD) spectroscopy is routinely used in the biopharmaceutical industry to study the effects of manufacturing, formulation, and storage conditions on protein conformation and stability, and these results are often included in regulat
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4607-4616
We report the identification and characterization of a novel degradation product associated with PEGylation of a recombinant protein. After several months of storage at 2°C–8°C, an unexpected increase was observed in the proportion of an impurity