Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Edward W. Moore"'
Autor:
Gwendolyn Darby, Roger Secknus, Ann Chernosky, Edward W. Moore, Tatu Juvonen, R. Thomas Holzbach
Publikováno v:
Journal of Gastroenterology and Hepatology. 14:446-456
Background: Apolipoprotein A-I (Apo A-I), conventionally purified by several steps including organic solvent-delipidation from plasma, inhibits cholesterol crystallization in bile. To observe a significant effect in vitro, however, supraphysiological
Publikováno v:
Digestive Diseases and Sciences. 40:2220-2226
Secretion of gallbladder mucin is an important step in gallstone pathogenesis. Previous studies have demonstrated that aspirin and other nonsteroidal antiinflammatory drugs (NSAIDs) can both inhibit gallbladder mucin secretion and prevent gallstone f
Publikováno v:
Gastroenterology. 106:866-874
Background/Aims: The specific components of bile, which is necessary for normal calcium absorption, are unknown. We have previously shown that Ca 2+ is bound with high affinity by premicellar taurocholate. The current studies examined the effects of
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 266:G318-G323
The role of bile salts in intestinal Fe absorption has not previously been defined. We have recently shown that bile salts having cholanic ring 7 alpha-OH and/or 12 alpha-OH groups bind Fe2+ with high affinity at premicellar concentrations and also p
Publikováno v:
Hepatology. 14:701-706
Previous studies have strongly suggested that human bile contains a substance(s) that interferes with the precipitation of calcium phosphate and carbonate from solution. These studies, however, did not distinguish between calcium binding by biliary c
Publikováno v:
Gastroenterology. 99:1772-1778
Ceftriaxone, a semisynthetic third-generation cephalosporin, has recently been associated with biliary sludge formation. Analysis of the biliary concretions induced by this agent shows a calcium salt of ceftriaxone. The present in vitro studies were
Publikováno v:
Gastroenterology. 99:1452-1459
The most recognized function of the human gallbladder is to store bile. However, this organ is not a static reservoir. It actively modifies bile by two processes: concentration and acidification. This study was designed to simultaneously evaluate the
Publikováno v:
Surgery. 117(4)
Biliary calcium is known to play an important role in the pathogenesis of gallstones. Calcium salts are present in all pigment gallstones and are also present in the core of most, if not all, cholesterol gallstones.The effects of acute hypercalcemia
Autor:
Mitchell L. Shiffman, John M. Kellum, C C Schwartz, Robert D. Shamburek, Edward W. Moore, Harvey J. Sugerman
Publikováno v:
Gastroenterology. 105(4)
Background: Arachidonic acid (AA) and hydrophobic bile salts (BS) stimulate gallbladder mucin (GBM) secretion, which is thought to be an essential step in gallstone pathogenesis. The present study was performed to evaluate the relationship between AA
Publikováno v:
Gastroenterology. 103(1)
Changes in gallbladder bile composition that occurred in patients who developed gallstones during weight reduction were evaluated. Bile was sampled directly from the gallbladder in 11 morbidly obese patients with no gallstones at the time of gastric