Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Edward W. Carney"'
Autor:
Szabina A. Stice, Edward W. Carney
Ethylene glycol (EG) is a major industrial chemical used in the production of polyester fibers and films, antifreeze and vitrification formulations, and numerous other applications. This chapter describes the reproductive and developmental toxicity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd00cfc14655a14de65201d01d94a4a1
https://doi.org/10.1016/b978-0-323-89773-0.00040-0
https://doi.org/10.1016/b978-0-323-89773-0.00040-0
Autor:
Manoj Aggarwal, James Akingbasote, Arturo Anadón, Gregory J. Anger, Anthony E. Archibong, Irma Ares, Michael Aschner, Daiana S. Avila, Denise C. Bailey, Norman J. Barlow, Sudheer Beedanagari, P.P. Beltyukov, Karyn Bischoff, Carina Rodrigues Boeck, William M. Bracken, Emily Brehm, Richard M. Breyer, Susan Bright-Ponte, Mirjana Milosevic Brockett, Luisa Campagnolo, Edward W. Carney, Andrew Charrette, Sandrine Fleur Chebekoue, Catheryne Chiang, Wei-Chun Chou, Jane K. Cleal, Toby B. Cole, Daniel Cook, Robert W. Coppock, Lucio G. Costa, Margarita Curras-Collazo, Wanying Dai, Khoi Dao, Rosane Souza Da Silva, T. Zane Davis, Francisco Dominguez, Robin B. Doss, Margitta M. Dziwenka, Brian Enright, Carmen Estevan, Timothy J. Evans, Anna M. Fan, Marcelo Farina, Suzanne E. Fenton, Ayhan Filazi, Vanessa A. Fitsanakis, Rex FitzGerald, John Flaskos, Jodi A. Flaws, S.J.S. Flora, Vekataseshu K. Ganjam, Dale R. Gardner, Ramesh C. Garg, Jacqueline M. Garrick, Vincent F. Garry, Janee Gelineau-van Waes, Keith M. Godfrey, Yu V. Golubentseva, Roberto González-Martín, Benedict T. Green, Consuelo Guerri, Kavita Gulati, P.K. Gupta, Ramesh C. Gupta, Rekha K. Gupta, Najla Guthrie, Jeffery O. Hall, Alan J. Hargreaves, Kenneth J. Harris, Bridgett N. Hill, Corey J. Hilmas, Alan M. Hoberman, Karin S. Hougaard, Sinan Ince, Poorni R. Iyer, Nicklas R. Jacobsen, Starling Kalpana, Ramesh Kandimalla, Arthi Kanthasamy, Anumantha Kanthasamy, N.S. Khlebnikova, Nils Klüver, Prasada Rao S. Kodavanti, Kannan Krishnan, Shaila Kulkarni, Ozgur Kuzukiran, Rajiv Lall, Jessica Legradi, Rohan M. Lewis, Elise M. Lewis, Xin Li, Pinpin Lin, Bommanna G. Loganathan, Ivo F. Machado, Brinda Mahadevan, Susan L. Makris, Jitendra K. Malik, Ana Paula Marreilha dos Santos, Judit Marsillach, María Rosa Martínez-Larrañaga, María Aránzazu Martínez, Klara Matouskova, Roger O. McClellan, Dejan Milatovic, Ali Mustafa Mohammed, Thomas J. Montine, Peter Møller, Pushpinder Kaur Multani, Mingwei Ni, Efstathios Nikolaidis, Meliton N. Novilla, Stephanie Padilla, Carlos M. Palmeira, David Pamies, Manesh Kumar Panner Selvam, María Pascual, Jayant Patwa, Ashley Phillips, Micheline Piquette-Miller, V.B. Popov, M. Margaret Pratt, G.A. Protasova, Nishant Rai, João Ramalho-Santos, Aramandla Ramesh, Kausik Ray, Arunabha Ray, Aiguo Ren, Stephen J. Renaud, Drucilla J. Roberts, Lu Rongzhu, Magdalini Sachana, Heidi Sahlman, Nitin Saini, Vandna Saini, L.V. Shabasheva, Abha Sharma, Suresh C. Sikka, Marilyn Helen Silva, Ilker Simsek, Rajkumar Singh Kalra, Anita Sinha, Miguel A. Sogorb, Offie P. Soldin, Chunjuan Song, Ajay Srivastava, Szabina A. Stice, Tammy E. Stoker, Clinton A. Stonecipher, Sandra Szlapinski, Shihori Tanabe, Arun Tatiparthi, João Batista Teixeira da Rocha, Suresh Kumar Thokchom, Belen Tornesi, Vanda Torous, Peter Truran, Matthew C. Valdez, Laura N. Vandenberg, Neil Vargesson, Eugenio Vilanova, Kirsi H. Vähäkangas, Suryanarayana V. Vulimiri, Genoa R. Warner, Kevin D. Welch, Daniel C. Williams, Moges Woldemeskel, Jae-Ho Yang, Zhaobao Yin, Xiaoyou Ying, Begum Yurdakok-Dikmen, Snjezana Zaja-Milatovic, Changqing Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0dc2704509109027fc26dbd683a5376
https://doi.org/10.1016/b978-0-323-89773-0.01002-x
https://doi.org/10.1016/b978-0-323-89773-0.01002-x
Autor:
Menghang Xia, Robert G. Ellis-Hutchings, Jill A Franzosa, Nancy C. Baker, Edward W. Carney, Todd J. Zurlinden, Raja S. Settivari, Thomas B. Knudsen, Richard M. Spencer, Katerine S. Saili, Nicole Kleinstreuer, Shuaizhang Li
Publikováno v:
Curr Opin Toxicol
The more than 80,000 chemicals in commerce present a challenge for hazard assessments that toxicity testing in the 21(st) century strives to address through high-throughput screening (HTS) assays. Assessing chemical effects on human development adds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cde42be6e0dcaccb490d07266d4eca8
https://doi.org/10.1016/j.cotox.2019.04.004
https://doi.org/10.1016/j.cotox.2019.04.004
Autor:
Amanda K. Parks, Barun Bhhatarai, Sue Marty, Edward W. Carney, Daniel M. Wilson, Paul S. Price
Publikováno v:
Environmental Health Perspectives
Background: Integrative testing strategies (ITSs) for potential endocrine activity can use tiered in silico and in vitro models. Each component of an ITS should be thoroughly assessed. Objectives: We used the data from three in vitro ToxCast™ bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26983d22abe6edee19b7ea5c2e9f31b6
https://doi.org/10.1289/ehp184
https://doi.org/10.1289/ehp184
Publikováno v:
Chemical Research in Toxicology. 29:810-822
Assessment of ocular irritation is an essential component of any risk assessment. A number of (Q)SARs and expert systems have been developed and are described in the literature. Here, we focus on three in silico models (TOPKAT, BfR rulebase implement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccd4bc1654991b5cad5c7cb595c0c9d
https://doi.org/10.1021/acs.chemrestox.5b00531
https://doi.org/10.1021/acs.chemrestox.5b00531
Autor:
Patric Amcoff, Michael Schwarz, Hubert Deluyker, Julien Burton, Terry W Schultz, Andrew Worth, Mark T. D. Cronin, Alfonso Lostia, Andrew White, Romualdo Benigni, Edward W. Carney, Ivan Rusyn, Elisabet Berggren, Gerrit Schüürmann, Georges E. N. Kass, Karen Blackburn, Richard S. Judson, Francoise Gautier, Derek Knight, Sharon Munn, Catherine Mahony, Werner Lilienblum, Detlef Keller
Publikováno v:
Environmental Health Perspectives
Background Safety assessment for repeated dose toxicity is one of the largest challenges in the process to replace animal testing. This is also one of the proof of concept ambitions of SEURAT-1, the largest ever European Union research initiative on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b990286a6500180b60b4df8d8c5c228
https://doi.org/10.1289/ehp.1409342
https://doi.org/10.1289/ehp.1409342
Comparative Response of Rat and Rabbit Conceptuses In Vitro to Inhibitors of Histiotrophic Nutrition
Autor:
Edward W. Carney, Kamin J. Johnson, Belen Tornesi, Nigel P. Moore, Valerie A. Marshall, Reza J. Rasoulpour
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 104:1-10
Histiotrophic nutrition via the visceral yolk sac is an essential nutritional pathway of the rodent conceptus, and inhibition of this pathway may cause growth retardation, malformations, and death in rodent embryos. Morphologic differences among spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3da39920938d1d3fd2b7930cee6b95
https://doi.org/10.1002/bdrb.21134
https://doi.org/10.1002/bdrb.21134
Autor:
Thomas B. Knudsen, Raja S. Settivari, Alene T. McCoy, Jill A Franzosa, Edward W. Carney, Robert G. Ellis-Hutchings, Nicole Kleinstreuer
Embryonic vascular disruption is an important adverse outcome pathway (AOP) as chemical disruption of cardiovascular development induces broad prenatal defects. High throughput screening (HTS) assays aid AOP development although linking in vitro data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3cbe61957d8a1ab74cb657b8da3bcd
https://europepmc.org/articles/PMC6706853/
https://europepmc.org/articles/PMC6706853/
Autor:
Manoj Aggarwal, Shruti Agrawal, Arturo Anadón, Gregory J. Anger, Anthony E. Archibong, Irma Ares, Michael Aschner, Daiana S. Avila, Denise C. Bailey, Nancy C. Baker, Norman J. Barlow, Sudheer Beedanagari, Karyn Bischoff, William M. Bracken, Emily Brehm, Richard M. Breyer, Susan Bright-Ponte, Luisa Campagnolo, Edward W. Carney, Victor Castellano, Sandrine Fleur Chebekoue, Catheryne Chiang, Wei-Chun Chou, Supratim Choudhuri, Jane K. Cleal, Robert W. Coppock, Lucio G. Costa, Margarita Curras-Collazo, João Batista Teixeira da Rocha, Rosane S. Da Silva, T. Zane Davis, Robin B. Doss, Margitta M. Dziwenka, Brian Enright, Per Eriksson, Carmen Estevan, Timothy J. Evans, Bengt Fadeel, Anna M. Fan, Ali S. Faqi, Marcelo Farina, Suzanne E. Fenton, Maureen H. Feuston, Ayhan Filazi, Vanessa A. Fitsanakis, John Flaskos, Jodi A. Flaws, Swaran J.S. Flora, Vekataseshu K. Ganjam, Dale R. Gardner, Nicole M. Gardner, Ramesh C. Garg, Vincent F. Garry, Janee Gelineau-van Waes, Keith M. Godfrey, Consuelo Guerri, Marina Guizzetti, Kavita Gulati, Mary Gulumian, Pawan K. Gupta, Ramesh C. Gupta, Rekha K. Gupta, Sharon M. Gwaltney-Brant, Jeffrey O. Hall, Deborah K. Hansen, Alan J. Hargreaves, Kenneth J. Harris, Alan M. Hoberman, Karin S. Hougaard, Sinan Ince, Amy L. Inselman, Poorni Iyer, Nicklas R. Jacobsen, Valerian E. Kagan, Starling Kalpana, Kotaro Kaneko, Anumantha Kanthasamy, Arthi Kanthasamy, Vesa Karttunen, Hyung Sik Kim, Thomas B. Knudsen, Prasada Rao S. Kodavanti, Kannan Krishnan, Shaila Kulkarni, Rajiv Lall, Michelle A. Lasher, Scott B. Laudert, Byung-Mu Lee, Jessica Legradi, Maxwell C.K. Leung, Elise M. Lewis, Rohan M. Lewis, Xin Li, Pinpin Lin, Bommanna G. Loganathan, Jan Ludvig Lyche, Robert C. MacPhail, Brinda Mahadevan, Jitendra K. Malik, Ana Paula Marreilha dos Santos, Maria Aranzazu Martínez, Maria Rosa Martínez-Larrañaga, David McClary, Fabiano P. Menezes, Jerrold S. Meyer, Dejan Milatovic, Ida R. Miller Mukherjee, Ali Mustafa Mohammed, Peter Møller, Thomas J. Montine, Mingwei Ni, Efstathios Nikolaidis, Meliton N. Novilla, Stephanie Padilla, Carlos M. Palmeira, David Pamies, Kip E. Panter, María Pascual, Claudia Pellacani, Brian J. Piper, Micheline Piquette-Miller, Vadim B. Popov, M. Margaret Pratt, Galina A. Protasova, Nishant Rai, João Ramalho-Santos, Aramandla Ramesh, Arunabha Ray, Kausik Ray, Aiguo Ren, Stephen J. Renaud, Ronald T. Riley, Drucilla J. Roberts, Lu Rongzhu, Magdalini Sachana, Kai M. Savolainen, Lilia V. Shabasheva, Kathleen T. Shiverick, Suresh C. Sikka, Miguel A. Sogorb, Offie P. Soldin, Chunjuan Song, Ajay Srivastava, Szabina A. Stice, Tammy E. Stoker, Jaideep S. Toor, Belen Tornesi, Peter Truran, Kirsi Vähäkangas, Joseph Valdez, Neil Vargesson, Henrik Viberg, Eugenio Vilanova, Kenneth A. Voss, Suryanarayana V. Vulimiri, Kevin D. Welch, Daniel C. Williams, Moges Woldemeskel, Jae-Ho Yang, Zhaobao Yin, Xiaoyou Ying, Begum Yurdakok-Dikmen, Snjezana Zaja-Milatovic, Changqing Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3ec8a26b57cd9932d33f7fbce32e1a
https://doi.org/10.1016/b978-0-12-804239-7.01002-7
https://doi.org/10.1016/b978-0-12-804239-7.01002-7
Autor:
Robert G, Ellis-Hutchings, Raja S, Settivari, Alene T, McCoy, Nicole, Kleinstreuer, Jill, Franzosa, Thomas B, Knudsen, Edward W, Carney
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 71
Embryonic vascular disruption is an important adverse outcome pathway (AOP) as chemical disruption of cardiovascular development induces broad prenatal defects. High-throughput screening (HTS) assays aid AOP development although linking in vitro data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b37185d49fbeec430b2a6e32de8586
https://pubmed.ncbi.nlm.nih.gov/28414088
https://pubmed.ncbi.nlm.nih.gov/28414088