Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Edward W Hillhouse"'
Autor:
Vanlata Patel, Raghu Adya, Jing Chen, Manjunath Ramanjaneya, Muhammad F Bari, Sunil K Bhudia, Edward W Hillhouse, Bee K Tan, Harpal S Randeva
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87102 (2014)
AimsFibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease. We therefore i
Externí odkaz:
https://doaj.org/article/1e31b47f830c4c7d9cea277508f5121a
Autor:
Dimitris K. Grammatopoulos, Jing Chen, Danijela Markovic, Edward W. Hillhouse, Emmanouil Karteris
Publikováno v:
Endocrinology. 151:4959-4968
Copyright © 2010 by The Endocrine Society. Two types of CRH receptors mediate the diverse biological functions of CRH and CRH-related peptides. The type 1 CRH-R (CRH-R1) is extensively targeted by pre-mRNA splicing mechanisms that give rise to multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912b7641ed97c2d2edc0a1f328635421
https://doi.org/10.1210/en.2010-0622
https://doi.org/10.1210/en.2010-0622
Autor:
Danijela Markovic, Dimitris K. Grammatopoulos, Michael A. Levine, Margaret E. Hewitt, Thalia Teli, Edward W. Hillhouse
Publikováno v:
Cellular Signalling. 20:40-49
Mammalian adaptive mechanisms to stressful stimuli involve release of corticotropin-releasing hormone (CRH) and downstream activation of specific G-protein-coupled 7 transmembrane domain receptors. These CRH receptors (CRH-R) are expressed as multipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d32726d791a0363eb88150a008c26e
https://doi.org/10.1016/j.cellsig.2007.08.014
https://doi.org/10.1016/j.cellsig.2007.08.014
Autor:
Jing Dong, Edward W. Hillhouse, Harpal S. Randeva, Emmanouil Karteris, Sevasti Zervou, Yefei Pang, Peter Thomas
Publikováno v:
Molecular Endocrinology. 20:1519-1534
Progestin withdrawal is a crucial event for the onset of labor in many mammalian species. However, in humans the mechanism of a functional progestin withdrawal is unclear, because progestin concentrations do not drop in maternal plasma preceding labo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9306c2518f9698ab922e49e13b6bc770
https://doi.org/10.1210/me.2005-0243
https://doi.org/10.1210/me.2005-0243
Autor:
Emmanouil Karteris, Janet E. Digby, Edward W. Hillhouse, Sevasti Zervou, Jing Chen, Manu Vatish, Bee K. Tan, Harpal S. Randeva
Publikováno v:
Diabetologia. 49:1292-1302
Pregnancy, a state of insulin resistance, is associated with elevated levels of cytokines and profound alterations in metabolism. Serum adiponectin, an adipokine with anti-inflammatory and insulin-sensitising properties, has been shown to be lower in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078decfa8dea1ade05b027380b271515
https://doi.org/10.1007/s00125-006-0194-7
https://doi.org/10.1007/s00125-006-0194-7
Publikováno v:
Clinical Medicine. 5:585-588
At the birth of the new millennium Britain's Labour government published a 10-year plan for modernising the National Health Service (NHS), placing great emphasis on new ways of working. As part of this process, and following extensive negotiation, ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39a58b0d47f41d924bb32fed17335a8
https://doi.org/10.7861/clinmedicine.5-6-585
https://doi.org/10.7861/clinmedicine.5-6-585
Autor:
Jing Chen, Sevasti Zervou, Rachel J. Machado, Harpal S. Randeva, Emmanouil Karteris, Edward W. Hillhouse
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 288:E1089-E1100
Although starvation-induced biochemical and metabolic changes are perceived by the hypothalamus, the adrenal gland plays a key role in the integration of metabolic activity and energy balance, implicating feeding as a major synchronizer of rhythms in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea0d6f795e1c1aa9e898e897a20a119
https://doi.org/10.1152/ajpendo.00351.2004
https://doi.org/10.1152/ajpendo.00351.2004
Autor:
Dimitris K. Grammatopoulos, Danijela Markovic, Edward W. Hillhouse, Michael A. Levine, Thalia Teli
Publikováno v:
Molecular Endocrinology. 19:474-490
Attenuation of CRH receptor type 1 (CRH-R1) signaling activity might involve desensitization and uncoupling of CRH-R1 from intracellular effectors. We investigated the desensitization of native CRH-R in human myometrial cells from pregnant women and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47964b6b9fb130fc81d3b806a606769
https://doi.org/10.1210/me.2004-0275
https://doi.org/10.1210/me.2004-0275
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 111:1218-1228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e2c75a2ed458f182f5c0edad7e0d2bf
https://doi.org/10.1111/j.1471-0528.2004.00412.x
https://doi.org/10.1111/j.1471-0528.2004.00412.x
Autor:
Edward W. Hillhouse, Kelly L. Parham, Robert W. Old, Sevasti Zervou, Emmanouil Karteris, R. D. Catalano
Publikováno v:
Endocrinology. 145:3971-3983
We report the full genomic organization of the human gene for the corticotropin-releasing factor (CRF) receptor type 1 (CRFR1), with complete mapping of exons 1–14. The 5′ flanking region (2.4 kb) of the gene encoding for human CRFR1 was isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92984399170b38e7bb9e843bafb7ce86
https://doi.org/10.1210/en.2004-0194
https://doi.org/10.1210/en.2004-0194