Virtual Biopsy in Soft Tissue Sarcoma. How Close Are We?

Autor: Amani Arthur, Edward W. Johnston, Jessica M. Winfield, Matthew D. Blackledge, Robin L. Jones, Paul H. Huang, Christina Messiou

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

A shift in radiology to a data-driven specialty has been unlocked by synergistic developments in imaging biomarkers (IB) and computational science. This is advancing the capability to deliver “virtual biopsies” within oncology. The ability to non

Externí odkaz: https://doaj.org/article/3806728772e24bec9b7a8f905126e540

Avoiding Unnecessary Biopsy after Multiparametric Prostate MRI with VERDICT Analysis: The INNOVATE Study

Autor: Saurabh Singh, Harriet Rogers, Baris Kanber, Joey Clemente, Hayley Pye, Edward W. Johnston, Tom Parry, Alistair Grey, Eoin Dinneen, Greg Shaw, Susan Heavey, Urszula Stopka-Farooqui, Aiman Haider, Alex Freeman, Francesco Giganti, David Atkinson, Caroline M. Moore, Hayley C. Whitaker, Daniel C. Alexander, Eleftheria Panagiotaki, Shonit Punwani

Publikováno v: Radiology. 305:623-630

Background In men suspected of having prostate cancer (PCa), up to 50% of men with positive multiparametric MRI (mpMRI) findings (Prostate Imaging Reporting and Data System [PI-RADS] or Likert score of 3 or higher) have no clinically significant (Gle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9f6cf177948a23cda37b6a20860c17
https://doi.org/10.1148/radiol.212536

Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth

Autor: Emma Scott, Kirsty Hodgson, Beatriz Calle, Helen Turner, Kathleen Cheung, Abel Bermudez, Fernando Jose Garcia Marques, Hayley Pye, Edward Christopher Yo, Khirul Islam, Htoo Zarni Oo, Urszula L. McClurg, Laura Wilson, Huw Thomas, Fiona M. Frame, Margarita Orozco-Moreno, Kayla Bastian, Hector M. Arredondo, Chloe Roustan, Melissa Anne Gray, Lois Kelly, Aaron Tolson, Ellie Mellor, Gerald Hysenaj, Emily Archer Goode, Rebecca Garnham, Adam Duxfield, Susan Heavey, Urszula Stopka-Farooqui, Aiman Haider, Alex Freeman, Saurabh Singh, Edward W. Johnston, Shonit Punwani, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna Harries, Denisa Bogdan, Daniel Westaby, Gemma Fowler, Penny Flohr, Wei Yuan, Adam Sharp, Johann de Bono, Norman J. Maitland, Simon Wisnovsky, Carolyn R. Bertozzi, Rakesh Heer, Ramon Hurtado Guerrero, Mads Daugaard, Janne Leivo, Hayley Whitaker, Sharon Pitteri, Ning Wang, David J. Elliott, Benjamin Schumann, Jennifer Munkley

Publikováno v: Scott, E, Hodgson, K, Calle, B, Turner, H, Cheung, K, Bermudez, A, Marques, F J G, Pye, H, Yo, E C, Islam, K, Oo, H Z, McClurg, U L, Wilson, L, Thomas, H, Frame, F M, Orozco-Moreno, M, Bastian, K, Arredondo, H M, Roustan, C, Gray, M A, Kelly, L, Tolson, A, Mellor, E, Hysenaj, G, Goode, E A, Garnham, R, Duxfield, A, Heavey, S, Stopka-Farooqui, U, Haider, A, Freeman, A, Singh, S, Johnston, E W, Punwani, S, Knight, B, McCullagh, P, McGrath, J, Crundwell, M, Harries, L, Bogdan, D, Westaby, D, Fowler, G, Flohr, P, Yuan, W, Sharp, A, de Bono, J, Maitland, N J, Wisnovsky, S, Bertozzi, C R, Heer, R, Guerrero, R H, Daugaard, M, Leivo, J, Whitaker, H, Pitteri, S, Wang, N, Elliott, D J, Schumann, B & Munkley, J 2023, ' Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth ', Oncogene, vol. 42, pp. 926–937 . https://doi.org/10.1038/s41388-023-02604-x

Prostate cancer is the most common cancer in men and it is estimated that over 350,000 men worldwide die of prostate cancer every year. There remains an unmet clinical need to improve how clinically significant prostate cancer is diagnosed and develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae09a3648b677fb4f00e9f89464d3260

Starting CT-guided robotic interventional oncology at a UK centre

Autor: Edward W Johnston, Jodie Basso, Jessica Winfield, James McCall, Nasir Khan, Christina Messiou, Dow-Mu Koh, Nicos Fotiadis

Publikováno v: The British journal of radiology. 95(1134)

Objective A commercially available CT-guided robot offers enhanced abilities in planning, targeting, and confirming accurate needle placement. In this short communication, we describe our first UK experience of robotic interventional oncology procedu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ece73416808de6c206457289da9f5fc
https://pubmed.ncbi.nlm.nih.gov/35290098

Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial

Autor: Vicky Goh, Alistair Rienhardt, Priya Limbu, Veronica A. Morgan, Beth Shepherd, David J. Breen, Kayleigh Gilbert, Paul Nichols, Lisa Woodrow, Neal Navani, Sophia Hans, Stephen Karp, Ruth E.C. Evans, Chris Everitt, Andrew Gogbashian, Elizabeth Chang, Nina Tunariu, Amelia Daniel, Elizabeth Hadley, Tina Mills-Baldock, Clare Collins, Ibiyemi Olaleye, Shraddha Weir, Martha Handousa, Rob Glynne-Jones, Steve Halligan, Antony Higginson, Uday Patel, Azmina Verjee, Aji Kavidasan, Sarah Howling, Andrew Bateman, Priscilla Phiri, Imogen Locke, Lyn Blakeway, Joanne Kellaway, Abel Jalloh, Elizabeth Green, Helen Pardoe, Simon Ball, Reyes Lauigan, Jonathan Wilson, Dominic Blunt, U. Ekeowa, Amy Davis, Jon Robinson, S. Burke, Prital Patel, Marian Duggan, Harbir S. Sidhu, Farzana Rahman, Sofia Gourtsoyianni, Shaki Balogun, Pippa Riddle, Peter Boavida, Colin Elton, Stefania Stegner, Daniel J. Smith, Zoltan Nagy, Suzanne Chukundah, Jenna Couture, Laura L. Quinn, Terry O'Shaughnessy, Revanth Jannapureddy, Heather Hughes, Shonit Punwani, Subramanian Ramesh, Anne Miles, Sajid A. Khan, Michelle Saull, Stuart A. Taylor, Tanjil Nawaz, Khawaja Shahabuddin, Andy Lowe, Gauraang Bhatnagar, James Crosbie, Thida Win, Rashidat Adeniba, Helen Beedham, Sahar Naaseri, Nicola Lucas, Fiona McKirdy, Abby Sharp, Lorraine Hurl, Nicola Gibbons, Laura Hughes, Alison Morton, William Partridge, Amy Smith, Krystyna Reczko, Rudi Borgstein, Ann O'Callaghan, Davide Prezzi, Ayshea Hameeduddin, Nelesh Jeyadevan, Matthew Train, John O'Donohue, Teresa Light, Shahanara Ferdous, Austen Obichere, Caroline S. Clarke, Wivijin Piga, Anita Rhodes, Ian C Simcock, Meena Reddi, Shanna Wilson, John Bridgewater, Keyury Desai, Anwar R. Padhani, Maureen Furneaux, Raj Srirajaskanthan, Kishor Barhate, Anita Amadi, Sandy Beare, Dorothee Boisfer, Ferrial Syeed, Elizabeth Isaac, Amjad Mohammed, Katie Prior, Mohamed A. Thaha, Jonathan McCullogh, Kara Sargus, Andrea Rockall, Clive Kay, David Chao, Eleni Ntala, J. James Stirling, Dow-Mu Koh, David Birch, Adrian Green, Marie Jackson, Sanjaya Wijeyekoon, Girija Anand, Hameed Rafiee, Ali Mohammed, Richard Beable, William Ricketts, Liane Davis, Shafi Ahmed, Tina Stoycheva, Sally O'Connor, Jamila Roehrig, Steve Ellis, Catherine Norman, Balinder Hans, Nishat Bharwani, Peter Russell, Kitrick Perry, Ellice Marwood, Alfred Oliver, Stephen Morris, Veronica Conteh, Eleni Karapanagiotou, Saba Mahmud, Sidra Tulmuntaha, Christian Kelly-Morland, Alice Johnson, Sasithar Maheswaran, Farid Bazari, Yvonne Campbell, Rajapandian Ilangovan, Adnam Alam, Tuck-Kay Loke, Susan Mallett, G. Atkin, Nicola H. Strickland, Dominic Yu, Ashley M. Groves, Chloe van Someren, Ian Jenkins, Kai-Keen Shiu, Colm Prendergast, Sherif Raouf, Jagadish Kalasthry, David Snell, Nathalie Rich, Louise Lim, Michael Long, Edward W. Johnston, Kathryn Tarver, Sam M. Janes, Laletha Agoramoorthy, Rommel Butawan, Pooja Datt, Jonathan Teague, Christopher Wanstall, Jane De Los, Sara Lock, Adoracion Jayme, Alec Engledow, Janet McGowan, Andre Nunes, Akosa Aboagye, Howard Curtis, Teresita Beeston, Angshu Bhowmik, Gule Hanid, E. Scurr, Payal Julka, Lesley Honeyfield, Aileen Austria, Celia Simeon, Katherine van Ree, Adesewa Onajobi, Lara Curry

Publikováno v: 2019, ' Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer : the prospective Streamline C trial ', The Lancet Gastroenterology & Hepatology, vol. 4, no. 7, pp. 529-537 . https://doi.org/10.1016/S2468-1253(19)30056-1
The Lancet. Gastroenterology & Hepatology

BACKGROUND: Whole-body MRI (WB-MRI) could be an alternative to multimodality staging of colorectal cancer, but its diagnostic accuracy, effect on staging times, number of tests needed, cost, and effect on treatment decisions are unknown. We aimed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31de387a268225c5c35050cd5154377f
https://doi.org/10.1016/s2468-1253(19)30056-1