Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Edward T Lally"'
Autor:
Edward T Lally, Kathleen Boesze-Battaglia, Anuradha Dhingra, Nestor M Gomez, Jinery Lora, Claire H Mitchell, Alexander Giannakakis, Syed A Fahim, Roland Benz, Nataliya Balashova
Publikováno v:
Pathogens, Vol 9, Iss 2, p 74 (2020)
Leukotoxin (LtxA), from oral pathogen Aggregatibacter actinomycetemcomitans, is a secreted membrane-damaging protein. LtxA is internalized by β2 integrin LFA-1 (CD11a/CD18)-expressing leukocytes and ultimately causes cell death; however, toxin local
Externí odkaz:
https://doaj.org/article/3b42aa3c64a64088b4cdb9eaa326111e
Autor:
Angela C Brown, Kathleen Boesze-Battaglia, Nataliya V Balashova, Nestor Mas Gómez, Kaye Speicher, Hsin-Yao Tang, Margaret E Duszyk, Edward T Lally
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205871 (2018)
The oral bacterium, Aggregatibacter actinomycetemcomitans, which is associated with localized aggressive periodontitis, as well as systemic infections including endocarditis, produces numerous virulence factors, including a repeats-in-toxin (RTX) pro
Externí odkaz:
https://doaj.org/article/bf5f26f4c76f4e40962a3b3b95ee4e4b
Autor:
Edward T. Lally, Nataliya Balashova, Syed A Fahim, Kathleen Boesze-Battaglia, Anuradha Dhingra, Nestor Mas Gomez, Roland Benz, Alexander Giannakakis, Claire H. Mitchell
Leukotoxin (LtxA) from oral pathogenAggregatibacter actinomycetemcomitansis a secreted membrane-damaging protein. LtxA is internalized by β2 integrin LFA-1 (CD11a/CD18) expressing leukocytes and ultimately causes cell death; however toxin localizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b04be12d09726c8d3e33bcd45083bc7
Autor:
Scott C. Kachlany, Angela C. Brown, Evan Koufos, Edward T. Lally, Eric Krueger, Justin B. Nice, Nataliya Balashova
Publikováno v:
Toxins
Volume 10
Issue 10
Toxins, Vol 10, Iss 10, p 414 (2018)
Volume 10
Issue 10
Toxins, Vol 10, Iss 10, p 414 (2018)
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, has been associated with localized aggressive periodontitis (LAP). In particular, highly leukotoxic strains of A. actinomycetemcomitans have been more closely associated with this di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6c5a44c75b31c2aaba372e53cffb1d
Autor:
Jiri Masin, Radim Osicka, Tomas Wald, Adriana Osickova, Edward T. Lally, En Hyung Chang, Evan Koufos, Alexander Giannakakis, Jana Roderova, Miroslav Šulc, Nataliya V. Balashova, Angela C. Brown
Publikováno v:
Emerging Microbes & Infections
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-15 (2018)
Emerging Microbes and Infections, Vol 7, Iss 1, Pp 1-15 (2018)
Kingella kingae is a member of the commensal oropharyngeal flora of young children. Improvements in detection methods have led to the recognition of K. kingae as an emerging pathogen that frequently causes osteoarticular infections in children and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96727f16a577d14e9ddd3378d5482553
https://pubmed.ncbi.nlm.nih.gov/30405113
https://pubmed.ncbi.nlm.nih.gov/30405113
Autor:
Irene R. Kieba, Edward T. Lally, Patrik Nygren, Angela C. Brown, Anuradha Dhingra, Kathleen Boesze-Battaglia, Nataliya Balashova
Publikováno v:
Cellular microbiology. 21(3)
Repeats-in-toxin leukotoxin (LtxA) produced by the oral bacterium Aggregatibacter actinomycetemcomitans kills human leukocytes in a lymphocyte function-associated antigen 1 (LFA-1, integrin α(L)/β(2))-dependent manner, although the mechanism for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e719721d7abdc16275fa9e2be4bc23
https://pubmed.ncbi.nlm.nih.gov/30329215
https://pubmed.ncbi.nlm.nih.gov/30329215
Publikováno v:
Journal of periodontology. 67
Recent studies of the dental plaque bacteria associated with the various forms of early-onset periodontitis confirm the importance of target periodontal pathogens such as Actinobacillus actinomycetemcomitans, Bacteroides forsythus, Prevotella interme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb4a2f1c8605866cd1762842a6e8d65
https://pubmed.ncbi.nlm.nih.gov/29539847
https://pubmed.ncbi.nlm.nih.gov/29539847
Publikováno v:
Journal of periodontology. 67
Actinobacillus actinomycetemcomitans has been implicated as a causative organism in early-onset periodontitis. The mechanisms by which A. actinomycetemcomitans is pathogenic are not known, but the organism produces several potential virulence factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0925718c88c99942df94f5811a6323
https://pubmed.ncbi.nlm.nih.gov/29539844
https://pubmed.ncbi.nlm.nih.gov/29539844
Autor:
Evan Koufos, Tsutomu Arakawa, Roland Benz, Edward T. Lally, Nataliya Balashova, Alexander Giannakakis, Angela C. Brown, Hsin-Yao Tang
Publikováno v:
Gene. 672
A leukotoxin (LtxA) that is produced by Aggregatibacter actinomycetemcomitans (Aa) is an important virulence determinant in an aggressive form of periodontitis in adolescents. Understanding the function of this protein at the molecular level is criti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9374361dbfca1a02bdc94e89d24276
https://pubmed.ncbi.nlm.nih.gov/29879499
https://pubmed.ncbi.nlm.nih.gov/29879499
Autor:
Desiree Alexander, Anuradha Dhingra, Juan Reyes-Reveles, Kathleen Boesze-Battaglia, Nishat Shahabuddin, Alvina Bragin, Jonathan Korostoff, Ignacio Blasi, Edward T. Lally, Bruce J. Shenker
Publikováno v:
Molecular Oral Microbiology. 31:486-500
Porphyromonas gingivalis often subverts host cell autophagic processes for its own survival. Our previous studies document the association of the cargo sorting protein, melanoregulin (MREG), with its binding partner, the autophagic protein, microtubu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb57361d4724d24c48e5f5be0aa3a98
https://doi.org/10.1111/omi.12141
https://doi.org/10.1111/omi.12141