Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Edward Seung"'
Autor:
Chen Sabrina Tan, Thomas A Broge, Edward Seung, Vlad Vrbanac, Raphael Viscidi, Jennifer Gordon, Andrew M Tager, Igor J Koralnik
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64313 (2013)
Progressive Multifocal Leukoencephalopathy (PML) is an often fatal disease caused by the reactivation of the JC virus (JCV). Better understanding of viral-host interactions has been hampered by the lack of an animal model. Engrafting NOD/SCID/IL-2-Rg
Externí odkaz:
https://doaj.org/article/8d60bc109c5b43f6a0249a1007b2ebb1
Autor:
Edward Seung, Timothy E Dudek, Todd M Allen, Gordon J Freeman, Andrew D Luster, Andrew M Tager
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77780 (2013)
An estimated 34 million people are living with HIV worldwide (UNAIDS, 2012), with the number of infected persons rising every year. Increases in HIV prevalence have resulted not only from new infections, but also from increases in the survival of HIV
Externí odkaz:
https://doaj.org/article/251cc994f0d24d63a6147675e272f1ce
Autor:
Edward Seung, Zhen Xing, Lan Wu, Ercole Rao, Virna Cortez-Retamozo, Beatriz Ospina, Liqing Chen, Christian Beil, Zhili Song, Bailin Zhang, Mikhail Levit, Gejing Deng, Andrew Hebert, Patrick Kirby, Aiqun Li, Emma-Jane Poulton, Rita Vicente, Audrey Garrigou, Peter Piepenhagen, Greg Ulinski, Michele Sanicola-Nadel, Dinesh S. Bangari, Huawei Qiu, Lily Pao, Dmitri Wiederschain, Ronnie Wei, Zhi-yong Yang, Gary J. Nabel
Publikováno v:
Nature. 603:328-334
Effective antitumour immunity depends on the orchestration of potent T cell responses against malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a13b2ddbf0dac11fa1c3a85d09c032
https://doi.org/10.1038/s41586-022-04439-0
https://doi.org/10.1038/s41586-022-04439-0
Autor:
Dana M. Lord, Katarina Radosevic, Christian Beil, Gregory Ulinski, Thomas Bertrand, Cendrine Lemoine, Zhi Yong Yang, Srinivas S. Rao, Ronnie Wei, Gejing Deng, Béatrice Cameron, Valeriya Posternak, Bailin Zhang, Paul Ferrari, Lan Wu, Zhili Song, Tarik Dabdoubi, Aiqun Li, Virna Cortez-Retamozo, Stéphanie Pouzieux, Marielle Chiron, Gary J. Nabel, Jennifer Fretland, Fangxian Sun, Anna Park, Nizar El-Murr, Rita Vicente, Elisa Francesconi, Ercole Rao, Peter A. Piepenhagen, Catherine Prades, Huawei Qiu, Edward Seung, Beatriz Ospina, Patrick Kirby, Ling Xu
Publikováno v:
Nature Cancer. 1:86-98
Despite the significant therapeutic advances provided by immune-checkpoint blockade and chimeric antigen receptor T cell treatments, many malignancies remain unresponsive to immunotherapy. Bispecific antibodies targeting tumor antigens and activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f644614eb889717e39b93a7807d9cc
https://doi.org/10.1038/s43018-019-0004-z
https://doi.org/10.1038/s43018-019-0004-z
Autor:
Edward Seung, Zhen Xing, Lan Wu, Ercole Rao, Virna Cortez-Retamozo, Beatriz Ospina, Liqing Chen, Christian Beil, Zhili Song, Bailin Zhang, Mikhail Levit, Gejing Deng, Andrew Hebert, Patrick Kirby, Aiqun Li, Emma-Jane Poulton, Rita Vicente, Audrey Garrigou, Peter Piepenhagen, Greg Ulinski, Michele Sanicola-Nadel, Dinesh S. Bangari, Huawei Qiu, Lily Pao, Dmitri Wiederschain, Ronnie Wei, Zhi-yong Yang, Gary J. Nabel
Publikováno v:
Nature. 604:E13-E13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdb1b04ab43a62eb0ef35df5f768fbec
https://doi.org/10.1038/s41586-022-04652-x
https://doi.org/10.1038/s41586-022-04652-x
Autor:
Zhi Yong Yang, Lan Wu, Zhen Xing, Ronnie Wei, Sri Vadde, Serena Masciari, Liqing Chen, Michele Sanicola-Nadel, Sukhvinder Sidhu, Virna Cortez-Retamozo, Lily Pao, Zhili Song, Dmitri Wiederschain, Vasiliki Pelekanou, Wenwen Sha, Dinesh S. Bangari, Edward Seung, Gary J. Nabel
Publikováno v:
Cancer Research. 81:1825-1825
Current HER2-targeted therapies have markedly improved the outcome of cancer patients with HER2 overexpressing tumors. However, these patients may eventually relapse or develop treatment resistance. In addition, HER2-low patients that are not eligibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc74f95cbbf026c0b0e2a996d011b226
https://doi.org/10.1158/1538-7445.am2021-1825
https://doi.org/10.1158/1538-7445.am2021-1825
Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia
Autor:
Daniel T. Claiborne, Katharine Krupp, Todd M. Allen, Edward Seung, Elizabeth F. Mellors, Karen A. Power, Timothy Dudek, Vladimir Vrbanac, David M. Knipe, Christian L. Boutwell, Andrew M. Tager, Musie Ghebremichael, Abigail Bisesi, Colby R. Maldini
Publikováno v:
Journal of virology. 93(20)
BLT (bone marrow-liver-thymus) humanized mice, which reconstitute a functional human immune system, develop prototypic human virus-specific CD8(+) T cell responses following infection with human immunodeficiency virus type 1 (HIV-1). We explored the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c74042920b06bb59b1a15502324c7
https://pubmed.ncbi.nlm.nih.gov/31375576
https://pubmed.ncbi.nlm.nih.gov/31375576
Publikováno v:
The Journal of Immunology. 186:6830-6838
Lung transplantation remains the only effective therapy for patients with end-stage pulmonary diseases. Unfortunately, acute rejection of the lung remains a frequent complication and is an important cause of morbidity and mortality. The induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f577eb3d0bddde0f42a34a3bd02dd94
https://doi.org/10.4049/jimmunol.1001049
https://doi.org/10.4049/jimmunol.1001049
Autor:
Michael H. Byrne, Yoichiro Iwakura, Bodduluri Haribabu, Yinan Lan, Nancy D. Kim, Richard C. Chou, Edward Seung, Andrew D. Luster, Christian D. Sadik
Publikováno v:
Immunity. 33:266-278
SummaryA large and diverse array of chemoattractants control leukocyte trafficking, but how these apparently redundant signals collaborate in vivo is still largely unknown. We previously demonstrated an absolute requirement for the lipid chemoattract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ac9896189c774c8880f32e0dd2183c
https://doi.org/10.1016/j.immuni.2010.07.018
https://doi.org/10.1016/j.immuni.2010.07.018
Autor:
Terry K. Means, Stephen B. Calderwood, Emmanouil Tampakakis, Nir Hacohen, Joseph El Khoury, Andrew D. Luster, Cameron R. Stewart, Suzanne E. Hickman, Lindsay Puckett, Read Pukkila-Worley, Melissa F. Tai, Eleftherios Mylonakis, Edward Seung, Kathryn J. Moore, Richard A. Colvin
Publikováno v:
The Journal of Experimental Medicine
Publisher
Publisher
Receptors involved in innate immunity to fungal pathogens have not been fully elucidated. We show that the Caenorhabditis elegans receptors CED-1 and C03F11.3, and their mammalian orthologues, the scavenger receptors SCARF1 and CD36, mediate host def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8ea31263ce67c3646d55e621ea15d5
https://doi.org/10.1084/jem.20082109
https://doi.org/10.1084/jem.20082109