In-House Packed Porous Graphitic Carbon Columns for Liquid Chromatography-Mass Spectrometry Analysis of N-Glycans

Autor: Clifford Young, Mark R. Condina, Matthew T. Briggs, Edward S. X. Moh, Gurjeet Kaur, Martin K. Oehler, Peter Hoffmann

Publikováno v: Frontiers in Chemistry, Vol 9 (2021)

Protein glycosylation is a common post-translational modification that modulates biological processes such as the immune response and protein trafficking. Altered glycosylation profiles are associated with cancer and inflammatory diseases, as well as

Externí odkaz: https://doaj.org/article/7292c60ab98f424b99a197b9f22169f2

Long-term intrathecal administration of morphine vs. baclofen: Differences in CSF glycoconjugate profiles using multiglycomics

Autor: Edward S X Moh, Krishnatej Nishtala, Sameera Iqbal, Vasiliki Staikopoulos, Dilip Kapur, Mark R Hutchinson, Nicolle H Packer

Publikováno v: Glycobiology. 32:50-59

Opioid use for treatment of persistent pain has increased dramatically over the past two decades, but it has not resulted in improved pain management outcomes. To understand the molecular mechanisms of opioids, molecular signatures that arise from op

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0b9e3ec9f5f21ae4d40dca70e203c4
https://doi.org/10.1093/glycob/cwab098

Deciphering the Kidney Matrisome: Identification and Quantification of Renal Extracellular Matrix Proteins in Healthy Mice

Autor: Umut Rende, Seong Beom Ahn, Subash Adhikari, Edward S. X. Moh, Carol A. Pollock, Sonia Saad, Anna Guller

Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2827

Precise characterization of a tissue’s extracellular matrix (ECM) protein composition (matrisome) is essential for biomedicine. However, ECM protein extraction that requires organ-specific optimization is still a major limiting factor in matrisome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7112f309f2361d30f56cabcc71e9835c
https://doi.org/10.3390/ijms24032827

Human disease glycomics: technology advances enabling protein glycosylation analysis – part 2

Autor: Christopher Ashwood, Nicolle H. Packer, Abdulrahman M. Shathili, Edward S. X. Moh, Arun V. Everest-Dass

Publikováno v: Expert Review of Proteomics. 15:341-352

Introduction: The changes in glycan structures have been attributed to disease states for several decades. The surface glycosylation pattern is a signature of physiological state of a cell. In this review we provide a link between observed substructu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188a8ddb9637ef9e3e41412bac540188
https://doi.org/10.1080/14789450.2018.1448710

Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers

Autor: Miyako Nakano, Morten Thaysen-Andersen, Manveen K. Sethi, Christopher Ashwood, Uwe Möginger, Zeynep Sumer-Bayraktar, Matthew T. Briggs, Michael Muders, Ian Loke, Saulo Recuero, Sayantani Chatterjee, Ling Y. Lee, Niclas G. Karlsson, Martin K. Oehler, Kathrin Stavenhagen, Jenny H. L. Chik, Katia R. M. Leite, Peter Hoffmann, Daniel Kolarich, Giuseppe Palmisano, Rebeca Kawahara, Miguel Srougi, Sarah Förster, Arun V. Everest-Dass, Katherine Wongtrakul-Kish, Barbara Adamczyk, Jodie L. Abrahams, Edward S. X. Moh, Simone Diestel, Merrina Anugraham, Mark P. Molloy, Vignesh Venkatakrishnan, Hannes Hinneburg, Nicolle H. Packer

Publikováno v: Chatterjee, S, Lee, L Y, Kawahara, R, Abrahams, J L, Adamczyk, B, Anugraham, M, Ashwood, C, Sumer-Bayraktar, Z, Briggs, M T, Chik, J H L, Everest-Dass, A, Förster, S, Hinneburg, H, Leite, K R M, Loke, I, Möginger, U, Moh, E S X, Nakano, M, Recuero, S, Sethi, M K, Srougi, M, Stavenhagen, K, Venkatakrishnan, V, Wongtrakul-Kish, K, Diestel, S, Hoffmann, P, Karlsson, N G, Kolarich, D, Molloy, M P, Muders, M H, Oehler, M K, Packer, N H, Palmisano, G & Thaysen-Andersen, M 2019, ' Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers ', Proteomics, vol. 19, no. 21-22, 1900010 . https://doi.org/10.1002/pmic.201900010
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

While aberrant protein glycosylation is a recognized characteristic of human cancers, advances in glycoanalytics continue to discover new associations between glycoproteins and tumorigenesis. This glycomics-centric study investigates a possible link

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904f61480fee4b744bfbbb8525e4a054
https://pubmed.ncbi.nlm.nih.gov/31419058